Isotretinoin

Molecule Description

Isotretinoin is a form of Vitamin A used to treat acne.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Isotretinoin

In treating severe acne (specifically nodular acne)
It is also used in the treatment of cancer of skin

Contraindications of Isotretinoin

When should one not use Isotretinoin

You are pregnant or planning pregnancy or breastfeeding or a women of childbearing age and not using contraception
You are allergic to Isotretinoin
Children less than 12 years
If you have liver disease
If you have very high levels of lipids (cholesterol, triglycerides) in your blood
If you have increased levels of Vitamin A in your body (hypervitaminosis A)
If you are taking tetracyclines (a type of antibiotic medicine)

Side effects of Isotretinoin

Common side effects of this drug are:

Chapped lips, dizziness, drowsiness, dry eyes, mouth or skin
Dry nose that may lead to nosebleeds, headache and temporary worsening of acne
Severe allergic reactions
Kidney problems
Jaundice
Abnormal hair growth
Bleeding, redness or swelling of the gums
Hearing problems or ringing in the ears and vision issues
Severe psychological disturbances including suicidal tendencies
Stomach and pancreas problems
Growth problems in children

Precautions and Warnings of Isotretinoin

Pregnancy

Can I take Isotretinoin during pregnancy?

Do not use if you are pregnant. This medicine is known to cause severe birth defects in the fetus. Hence, it is strictly avoided in a sexually active woman unless foolproof contraception methods are followed.

Breast Feeding

Can I take Isotretinoin while breastfeeding?

You must not take Isotretinoin if you are breastfeeding. The medicine is likely to pass into breast milk and may harm your baby.

Driving

Can I drive if I have consumed Isotretinoin?

Always be cautious when driving at night because this medicine may affect your night vision. It can also cause drowsiness and dizziness.

Alcohol

Can I consume alcohol with Isotretinoin?

It is unsafe to consume alcohol with Isotretinoin. It can cause elevated heartbeats, nausea and vomiting.

Other General Warnings

Talk to your doctor if

If you are a woman of childbearing age, strictly use contraception, this medicine can cause serious harm to an unborn baby
Do not plan pregnancy immediately after stopping this medicine as some amount of medicine continues to stay in the body even after finishing the treatment
While taking this medicine, if you experience depression or aggressive tendencies or mood changes or thoughts about hurting yourself or ending your life; immediately inform your doctor
This medicine can increase the liver enzymes or blood cholesterol
This medicine causes extreme dryness of skin. Use moisturizer
Your skin may become sensitive to sunlight, avoid excessive sun exposure
If you experienced headache, vomiting stop the medication immediately and seek emergency medical care. It can be serious

Mode of Action of Isotretinoin

How Does It Work?

Isotretinoin decreases the amount of oil released by oil glands in your skin and helps your skin renew itself more quickly. Isotretinoin is used to treat severe nodular acne which is not responding to...

Interactions of Isotretinoin

Interactions with other medicines

Medicine like Tetracycline have additive effects
Effect of progesterone-only contraceptive pills might be reduced
Any other form of Vitamin A should be avoided along with this medicine and can cause overdose problems
Anti convulsion medications may decrease the effect of Isotretinoin

Interactions with food items

It is advisable to take along with food as it increases heartburn if taken on an empty stomach. Avoid oily and junk food for the overall effect.

Dietary Restrictions of Isotretinoin

No information is available on dietary restrictions while you are taking Isotretinoin, consult your doctor or pharmacist for further information.

Dosage of Isotretinoin

Overdose

Symptoms may include facial flushing, headache, dizziness, loss of balance, stomach pain and vomiting. Immediately seek for emergency medical help.

Missed a Dose

If you missed any dose, take it as soon as you remember. If it is time for your next dosage, then skip the missed dose. Do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Mahesh Muthe

MBBS

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Can I take this medicine without a prescription?

A: No. This medicine should only be taken with a prescription. Continuation of treatment requires a new prescription.

Q: I was taking Isotretinoin, and I realized I am pregnant what I should do?

A: Immediately stop taking this medicine and inform your doctor about your pregnancy. This medicine can seriously harm the unborn baby. The decision to continue or discontinue the pregnancy should be taken in consultation with your doctor as there are high chances of having a baby with defects.

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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