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Hydralazine+Isosorbide Dinitrate

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Molecule Summary

Uses
Heart failure
Therapy
Drugs For Congestive Heart Failure
Side Effects
Headache, dizziness, nausea, fatigue, low blood pressure
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Molecule Description

Hydralazine+Isosorbide Dinitrate is a medicine that is used to treat heart failure. It is a combination of two medicines called hydralazine and isosorbide dinitrate. These medicines work by relaxing the blood vessels, which makes it easier for your heart to pump blood. Hydralazine+Isosorbide Dinitrate is taken as directed by your doctor, with or without food. It is important to take it regularly, even if you feel well. Do not stop taking Hydralazine+Isosorbide Dinitrate without talking to your doctor first. Some common side effects of Hydralazine+Isosorbide Dinitrate include headache and dizziness. These side effects are usually mild and go away on their own. If you experience any severe side effects, contact your doctor right away.

Uses

Hydralazine+Isosorbide Dinitrate is used in the treatment of heart failure as an adjunct to standard therapy.

Contraindications

When should one not use Hydralazine+Isosorbide Dinitrate

  • If you are allergic to hydralazine, isosorbide dinitrate or any other ingredient of this medicine.
  • It should not be used in patients taking medicines containing sildenafil, avanafil, tadalafil or vardenafil (used for treating erectile dysfunction in men).
  • If you are taking a medicine called riociguat which is used to treat high blood pressure in the lungs (pulmonary hypertension).

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Nausea
  • Fatigue
  • Low blood pressure

Precautions and Warnings

Pregnancy

Pregnancy

Consult your doctor before taking Hydralazine+Isosorbide Dinitrate during pregnancy as limited information is present. Your doctor will only prescribe you this medicine if considered essential after assessing the benefits over risks.

Breast Feeding

Breast Feeding

Consult your doctor before taking Hydralazine+Isosorbide Dinitrate while breastfeeding as it is unknown if its components pass into the breastmilk.

Driving

Driving

It is advised not to drive if you have consumed Hydralazine+Isosorbide Dinitrate as you may experience dizziness after taking it.

Alcohol

Alcohol

You should avoid consuming alcohol while taking Hydralazine+Isosorbide Dinitrate, as it may worsen the side effects of this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have heart-related problems.
  • You have severe kidney or liver problems.
  • You are having any surgery.
  • You have glaucoma (increased pressure in the eye).
  • You are undernourished.
  • You are suffering from hypothermia (a condition in which your body loses heat faster than it can produce).
  • You have suffered from bleeding in the brain.
  • You have an underactive thyroid gland.
  • You experience headache, nausea, dizziness, fainting (symptomatic hypotension).
  • You experience any abnormal sensation on your skin such as numbness and tingling.
  • You have systemic lupus erythematosus (an autoimmune disorder), this medicine may induce this condition.
  • You suffer from a deficiency of an enzyme called glucose 6 phosphate dehydrogenase.

Mode of Action

How Does It Work?

Hydralazine+Isosorbide Dinitrate contains isosorbide dinitrate and hydralazine which work by relaxing the blood vessels and hence make the blood flow easy.

Dosage

Overdose

If you have taken an excess of Hydralazine+Isosorbide Dinitrate and experience side effects such as headache, uneven heart rhythm then contact your doctor immediately or go to the nearest hospital.

Missed a Dose

If you have missed taking a dose of Hydralazine+Isosorbide Dinitrate take it as soon as possible. Skip the dose if it's already time for the next dose. Do not double the dose.

Frequently Asked Questions (FAQs)

Hydralazine+Isosorbide Dinitrate may make you feel dizzy, so it is advised not to drive if you experience these side effects.

Hydralazine+Isosorbide Dinitrate is used for the treatment of heart failure as an adjunct to standard therapy.

Hydralazine+Isosorbide Dinitrate is a vasodilator which works by relaxing the blood vessels, making it easier for the heart to pump blood.

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