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Indapamide+Olmesartan Medoxomil

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Molecule Summary

Uses
High blood pressure
Therapy
Anti-Hypertensive
Side Effects
Vomiting, dizziness, excessive urination, headache, nausea, stomach pain
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Molecule Description

Indapamide+Olmesartan Medoxomil is a combination medicine used to treat high blood pressure by working on the kidneys and blood vessels. Indapamide is a diuretic that helps the kidneys remove excess water and salt from the body. This reduces the volume of blood the heart must pump, thereby lowering blood pressure and reducing strain on the heart. Olmesartan works by blocking the angiotensin II receptor, which normally constricts blood vessels. Relaxing and dilating the vessels facilitates blood flow and further reduces blood pressure. Together, these two actions help protect the heart, kidneys, and blood vessels from damage caused by hypertension. This medicine helps lower the risk of complications related to high blood pressure, such as heart attack, stroke, and kidney problems. Reducing fluid overload and relaxing blood vessels allows the heart to pump more efficiently and helps maintain stable blood pressure throughout the day. It is important to follow a low-salt diet and avoid alcohol while taking this medicine. These lifestyle steps complement the medication and help maintain better blood pressure control. Regular monitoring of blood pressure, kidney function, and electrolytes helps ensure that the medication is working effectively and safely. Patients should inform their doctor about all other medications, supplements, or herbal products they are taking, as some drugs can interact and affect the medicine's action or increase side effects. Taking the medicine at the same time each day and not missing doses helps maintain consistent blood pressure control and improves overall heart and kidney health.

Uses

Indapamide+Olmesartan Medoxomil is used in the treatment of high blood pressure.

Contraindications

When should one not use Indapamide+Olmesartan Medoxomil

  • If you are allergic to indapamide, olmesartan, or any other ingredients of Indapamide+Olmesartan Medoxomil.
  • If you are pregnant.
  • If you are suffering from jaundice.
  • If you have severe kidney disease.
  • If you are using any medicine containing aliskiren.

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Nausea
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Tiredness
  • Body pain
  • Chest pain
  • Flu-like symptoms
  • Cough
  • Runny or stuffy nose
  • Sore throat
  • Swelling
  • Blood in the urine

Precautions and Warnings

Pregnancy

Pregnancy

Indapamide+Olmesartan Medoxomil should not be taken during pregnancy. If you become pregnant while taking this medicine or wish to become pregnant, inform your doctor immediately.

Breast Feeding

Breast Feeding

Breastfeeding is not advisable if you are taking Indapamide+Olmesartan Medoxomil as the active ingredients of this medicine can pass into the breastmilk and affect the newborn.

Driving

Driving

Indapamide+Olmesartan Medoxomil can cause dizziness or fatigue, especially immediately after therapy initiation. Be cautious and avoid driving if you experience such symptoms.

Alcohol

Alcohol

It is not recommended for you to consume alcohol while on treatment with Indapamide+Olmesartan Medoxomil.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You suffer from any heart diseases.
  • You have kidney or liver problems.
  • You have diabetes or gallbladder problems.
  • You have diarrhoea and vomiting.
  • You are receiving high-dose diuretics (furosemide, hydrochlorothiazide).
  • You are on a low-salt diet.
  • Your doctor has told you that you have high blood potassium levels.
  • You have an adrenal gland disorder.
  • You are taking other medications to treat high blood pressure, such as Ramipril, Lisinopril, and Aliskiren.
  • Indapamide+Olmesartan Medoxomil is not recommended for children below the age of 6 years.

Mode of Action

How Does It Work?

  • Indapamide is a water pill. It works by acting on the kidneys. It increases urinary output, thereby increasing the excretion of water and salt from the body. This helps in reducing cardiac output and blood pressure.
  • Olmesartan works by blocking a substance in the body that causes blood vessels to tighten, thereby relaxing them and allowing blood to flow more easily.

Interactions

Interactions with other medicines

  • Before starting Indapamide+Olmesartan Medoxomil, inform your doctor about all the medicines you take, including herbal, vitamins & mineral supplements.
  • This medication, when taken with other antihypertensive medications such as benazepril, captopril, and lisinopril, may alter its effects.
  • Concomitant use along with medicines used in heart diseases and high blood pressure, like perindopril, candesartan, and aliskiren, may increase the risk of side effects with this medicine.
  • Concomitant use of this medicine with potassium supplements, medications such as amiloride, and spironolactone is not recommended, as it may increase blood potassium levels.
  • Medicines like aspirin, ibuprofen, etc, may lead to kidney failure when taken together with this medicine.
  • Lithium should not be taken simultaneously with this medicine.
  • This medicine should be taken at least 4 hours before Colesevelam (used to reduce blood cholesterol and fatty substances).

Interactions with food items

Indapamide+Olmesartan Medoxomil can be taken either before or after your meals.

Dosage

Overdose

If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you miss any dose of Indapamide+Olmesartan Medoxomil, take it as soon as you remember. However, if it is time for the next dose, then skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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