Granisetron
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Molecule Summary
| Uses | Nausea and vomiting associated with cancer medications, radiotherapy |
| Therapy | Anti-Emetic |
| Side Effects | Headache, constipation, diarrhoea, weakness |
Medicines
available
19k pincodes
Molecule Description
It is used in treating nausea and vomiting, which are associated with cancer medications, radiotherapy or any surgery. If you are allergic to this medicine, then avoid taking it. Take this medicine in doses and duration as prescribed by the doctor. Do not stop taking this medicine suddenly without informing your doctor. The common side effects of Granisetron are diarrhoea, headache and constipation. Most of which are temporary, but if you feel the side effects persist or your condition worsens, then you should contact your doctor immediately.
Uses
Granisetron is used to treat nausea and vomiting, which may be due to cancer medicines or radiotherapy.
Contraindications
When should one not use Granisetron
If you are allergic to Granisetron or any of the ingredients of Granisetron.
Side effects
Common side effects of this drug are:
- Headache
- Constipation
- Diarrhoea
- Weakness
- Lack of sleep
- Increased liver enzymes
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You may experience symptoms like vomiting, stomachache, constipation, difficulty in passing stools due to blockage in your intestine, as this medicine may reduce your bowel movement. Caution is exercised in patients with heart problems like irregular heartbeats.
- You are taking medicines like dolasetron, ondansetron along with granisetron, as there are chances of cross-sensitivity.
- You may experience symptoms like high body temperature, sweating, shivering, fits and confusion and other mental changes (serotonin syndrome), in such a situation, appropriate observation is required.
Mode of Action
How Does It Work?
After chemo or radiotherapy, serotonin is the main chemical substance responsible for vomiting. Granisetron works by inhibiting the action of this serotonin (body's chemical) and prevents the feeling of nausea and vomiting.
Interactions
Interactions with other medicines
- Simultaneous use of Granisetron along with medicines used to treat an irregular heartbeat, other medicines like dolasetron or ondansetron, can affect the heart activity.
- Concomitant use of Granisetron and medicines used to treat anxiety and to treat depression like fluoxetine, paroxetine, sertraline, venlafaxine, duloxetine, etc can cause symptoms like high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, etc. (serotonin syndrome).
Interactions with food items
Absorption of Granisetron is not influenced by any food.
Dosage
Overdose
- There are no symptoms of an overdose, but sometimes you may feel a mild headache.
- If you think you have taken too much of Granisetron and experience any unusual symptoms, then contact your doctor immediately or visit the nearest hospital.
Missed a Dose
- If you missed any dose of Granisetron, then take it as soon as you remember.
- If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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