Gliclazide+Metformin

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Molecule Description

Gliclazide+Metformin is a combination medicine. It is used in the treatment of type 2 diabetes mellitus. It helps in controlling the blood sugar levels adequately. This combination belongs to an anti-diabetic class of medicines. Gliclazide+Metformin is available in the form of tablet, capsule. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.

Uses

Gliclazide+Metformin is used for the treatment of type 2 diabetes mellitus.

Contraindications

When should one not use Gliclazide+Metformin

If you are allergic to gliclazide, metformin or similar medicines
If you have uncontrolled diabetes along with nausea, vomiting, diarrhoea, weight loss, stomach pain, etc
If you have diabetic pre-coma
If you have problems with your heart, liver or kidneys
If you have any severe infection
If you have a hereditary disease - porphyria
If you are suffering from dehydration
If you are taking a medicine called miconazole to treat fungal infections
If you consume alcohol in excess
If you are a breastfeeding mother

Side effects

Common side effects of this drug are:

Indigestion
Constipation
Blurred vision
Skin problems
Increased liver enzymes or jaundice

Precautions and Warnings

Pregnancy

It is not advised to use gliclazide+metformin during pregnancy, consult your doctor before using it.

Breast Feeding

Consult your doctor before using gliclazide+metformin while breastfeeding as it passes into breast milk in low amounts.

Driving

No information is available on the ability to drive or use machines, however, if you experience any side effect after taking gliclazide+metformin, then it is advisable not to drive or use machines. Contact your doctor for further information.

Alcohol

No information is available on the interactions of gliclazide+metformin when taken with alcohol. Consult your doctor for further information.

Other General Warnings

Talk to your doctor if

You have problems with your liver or kidney
You are at risk of having high blood sugar
You are suffering from any kind of infection
You have a blood enzyme deficiency (glucose-6-phosphate dehydrogenase deficiency)
You have a history of an allergic reaction
You are suffering from dehydration
You have undergone any surgery
Gliclazide+Metformin has not been studied in children and adolescents

Mode of Action

How Does It Work?

Gliclazide+Metformin acts by stimulating insulin secretion from the β-cells of the pancreas and increasing the amount of insulin released by the pancreas. It also helps to restore the body's proper response to the insulin it naturally produces.

Interactions

Interactions with other medicines

Some medicines can affect the way gliclazide+metformin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking water pills, oral contraceptives or are taking medicines used in psychiatric illness, tuberculosis fits or epilepsy.