Exenatide
Description
Exenatide is an anti-diabetic medicine that works like the natural hormone incr
etin in the body to help lower blood sugar levels in people with type 2 diabetes. It helps the pancreas release insulin when blood sugar is high, slows stomach emptying to reduce post-meal spikes in blood sugar, and decreases the amount of sugar produced by the liver. Exenatide is usually given as an injection and is used along with a healthy diet and regular exercise to improve blood sugar control. It may also support weight management in some patients. Like other diabetes medicines, it should be used under medical supervision, and patients should watch for side effects such as nausea, vomiting, or low blood sugar, particularly if taken with other anti-diabetic medications.
Uses
Contraindications
When should one not use Exenatide
Side effects
Common side effects of this drug are:
- Nausea, vomiting
- Low blood sugar (sudden sweating, shaking, fast heartbeat, tingling in hands and feet)
- Weight loss
- Diarrhea
- Headache
- Loss of appetite
- Constipation
- Abdominal Discomfort
- Flatulence (passing gas)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have Type 1 diabetes or diabetic ketoacidosis then this medicine should not be used
- You have severe problems with your stomach or inflammation of the pancreas
- You lost weight too quickly
- You are suffering from kidney disease or you are on dialysis
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Oral antidiabetic medicine (e.g. Sulfonylureas) and Meglitinides may increase the risk of low blood sugar
- Blood-thinner medicines like Warfarin
- Insulin
Interactions with food items
Dietary Restrictions
Dosage
Overdose
Missed a Dose
Content Details
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I discuss with my healthcare expert before taking Exenatide?
- Tell your doctor if:
- You are taking any other anti-diabetic medicine
- Allergic to this medicine
- Severe kidney disease (creatinine clearance; 30ml/min)
- Family history of Medullary thyroid cancer (A type of thyroid cancer)
Q: Should I be worried while on this medication?
References
- Ema. Exenatide.[Accessed 10 Sept.2019] (online):
- WebMD. Exenatide.[Accessed 10 Sept.2019] (online):
- Medscape. Exenatide.[Accessed 10 Sept.2019] (online):
- drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Exenatide. [Updated 2019 May 1]. :
- drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Exenatide. [Updated 2019 May 1]. :
- drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Exenatide. [Updated 2019 May 1]. :









