Doxofylline+Montelukast
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Molecule Summary
| Uses | Asthma |
| Therapy | Anti-Asthmatic |
| Side Effects | Headache, nausea, vomiting, stomach pain, diarrhoea |
Medicines
available
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Molecule Description
Doxofylline+Montelukast is a combination medication used to treat bronchial asthma in adults aged 15 years and older. It contains doxofylline and montelukast, which work together to widen the airways in the lungs, providing relief from asthma symptoms. This medication is not suitable for treating sudden asthma attacks and should not be substituted with other medications without consulting your doctor.
Before starting Doxofylline+Montelukast, inform your doctor about any existing medical conditions (such as liver, kidney, or heart disease), other medications you are taking (including supplements and herbal remedies), and your lifestyle habits (smoking, alcohol, caffeine consumption). If you experience any side effects while taking this medication, consult your doctor.
Uses
Doxofylline+Montelukast is used in adults to treat asthma (a condition in which the airway path of the lungs gets narrow due to swelling and causes difficulty in breathing).
Contraindications
When should one not use Doxofylline+Montelukast
- If you are allergic to doxofylline or montelukast or any other components of Doxofylline+Montelukast.
- If you have any heart problems like heart attack, blockage of heart vessels, low blood pressure.
- If you are a breastfeeding woman.
Side effects
Common side effects of this drug are:
- Headache
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
- Indigestion
- Dizziness
- Fever
- Weakness
- Rash
- Lack of sleep
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Your asthma or your condition gets worse.
- You have underlying medical conditions like liver or kidney-related disease, fits, overactive thyroid, mood swings, heart disorders, blood-related disease, stomach ulcers, etc.
- You have problems with your lungs like COPD (Chronic obstructive pulmonary disease).
- You have low levels of oxygen in your blood.
- You develop symptoms like cough, runny nose, sneezing, pins and needles or numbness of arms or legs, worsening of symptoms and/or rash.
- You are taking aspirin or other painkillers like ibuprofen, diclofenac, etc.
- You smoke daily.
- Doxofylline+Montelukast is not recommended for children below 15 years of age.
Mode of Action
How Does It Work?
- Doxofylline+Montelukast contains a combination of doxofylline and montelukast.
- Doxofylline is a bronchodilator that relaxes the muscles that surround the airways of the lungs and allows them to open up. It acts by inhibiting a chemical in the body, causing relaxation of the muscles in the lungs.
- Montelukast works by blocking certain natural substances called leukotrienes, which may cause allergies. It reduces swelling, relaxes airways and helps to make breathing easier, thus also helps in controlling the symptoms of asthma.
Interactions
Interactions with food items
Doxofylline+Montelukast can be taken with or without food, but it is generally recommended to take it after food to minimize the risk of stomach discomfort or upset.
Dosage
Overdose
Symptoms of an overdose are nausea, vomiting, stomach pain, sleepiness, headache, increased thirst, and altered mood. If you experience any of the symptoms or think you have taken too much of this medicine, then contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you have missed taking any dose of this medicine, then take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
Articles
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References:
- Montelukast 10 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 3 June 2026]
- Montelukast 10 mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 3 June 2026]
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 50942, Doxofylline. Retrieved January 6, 2025
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 5281040, Montelukast. Retrieved January 6, 2025
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