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Dobutamine

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Molecule Summary

Uses
Heart conditions
Therapy
Drugs For Congestive Heart Failure
Side Effects
Increased heart rate, chest pain, irregular heartbeat
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Molecule Description

Dobutamine is used in the short-term treatment of heart failure or cardiac decompensation due to insufficient blood circulation and weakened heart muscles. It stimulates the heart muscle and improves blood flow. Dobutamine belongs to a group of medicines known as inotropes, which make your heart beat more strongly.

Uses

  • Dobutamine is used in certain heart conditions such as open-heart surgery, heart failure, heart diseases, shock, etc.
  • It is also used as an alternative to exercising for stress testing the heart.

Contraindications

When should one not use Dobutamine

  • If you are allergic to dobutamine or any other ingredient of this medicine.
  • If you have high blood pressure due to a tumour near the kidney.
  • If you have certain heart and blood vessel-related disorders.

Side effects

Common side effects of this drug are:

  • Increased heart rate
  • Chest pain
  • Irregular heartbeat

Precautions and Warnings

Pregnancy

Pregnancy

Due to limited safety information, it is advised to tell your doctor if you are pregnant or think you may be pregnant while he prescribes you this medicine.

Breast Feeding

Breast Feeding

There is limited safety data available about the use of Dobutamine in breastfeeding mothers. Hence, it is advised to inform your doctor before starting the treatment with this medicine while breastfeeding.

Driving

Driving

Do not drive or do anything that requires mental focus until you know how this medicine affects you.

Alcohol

Alcohol

Although there is no known interaction with alcohol along with this medicine, it is important to consult your physician if you drink too often.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You recently had a heart attack.
  • You had a heart transplant.
  • You have any kind of heart disorder or unstable angina.
  • It is advised to be careful while doing any exercise or workout.
  • Children should be monitored cautiously during the treatment.

Mode of Action

How Does It Work?

Dobutamine has an inotropic effect that increases myocardial contractility and stroke volume, resulting in increased cardiac output, heart rate and blood pressure. It works by activating the receptors in the heart. This makes the heart pump blood with more strength and force and increases its pumping capacity in conditions such as heart failure.

Interactions

Interactions with other medicines

  • Dobutamine may interact with other medicines if taken along. Discuss with your doctor about all the medicines, supplements or herbal preparations you are taking.
  • In particular, if you are already taking certain medication for a heart disorder, anxiety or migraine, antiparkinson medicine like entacapone or anaesthetics.

Dosage

Overdose

This medicine will be given by your doctor or nurse. Therefore it is less likely to give you more or less of this medicine. However, symptoms of overdose may include nausea, vomiting, palpitations, shortness of breath, chest pain, etc. Immediately inform the doctor if you feel such symptoms.

Missed a Dose

You will be monitored by your doctor or nurse on when the medicine should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them.

Frequently Asked Questions (FAQs)

Dobutamine is used for the short-term treatment of heart failure or decompensation (a condition in which your heart is unable to pump a sufficient amount of blood) caused due to a weakened heart muscle.

Yes, it can be indicated for use in neonates to 18 years of age. The doctor will decide the specific dose depending on the severity of the underlying condition and age. Speak to your child's doctor if you have any concerns about the use of this medicine for your child.

No, it is not a steroid. Dobutamine belongs to a group of medicines known as inotropes, which make your heart beat more strongly.

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