Cyclandelate
Molecule Description
Cyclandelate belongs to a class of medicines known as ‘Vasodilators.’ This medi
cine helps relax blood vessels and improves blood flow.
Uses of Cyclandelate
- As supportive medicine for the treatment of conditions associated with poor blood flow, such as:
- Severe pain in the legs, especially on activity (intermittent claudication)
- Hardening and narrowing of large arteries supplying blood to the stomach (abdominal aorta) or smaller arteries supplying blood to the hands, legs (arteriosclerosis obliterans)
- Any conditions causing poor blood flow to the brain (cerebrovascular diseases)
- Blood clots in veins obstructing the blood flow (thrombophlebitis)
- Discoloration of fingers and toes due to poor blood flow (Raynaud’s disease)
Contraindications of Cyclandelate
When should one not use Cyclandelate
- Allergy to Cyclandelate or any of its components
- Severe heart or brain diseases associated with impaired blood flow
- Bleeding disorders
Side effects of Cyclandelate
Common side effects of this drug are:
- Stomach upset, gas in the stomach, heartburn (due to reflux of stomach acid)
- Skin redness (flushing), weakness, faster heart rate
- Any serious allergic reaction like swelling of hands, face, or mouth, abnormal voice changes, trouble breathing or swallowing, rashes, itching, blisters of skin (serious, but rare)
Precautions and Warnings of Cyclandelate
Pregnancy
Q:
Can I take Cyclandelate during pregnancy?
A:
You should not take Cyclandelate during pregnancy, as enough data is not available on safety of
this medicine for use during pregnancy
Breast Feeding
Q:
Can I take Cyclandelate while breastfeeding?
A:
It is probably unsafe to take Cyclandelate if you are breastfeeding or plan to breastfeed, as no data is available on the safety of this medicine in nursing mothers.
Driving
Q:
Can I drive if I have consumed Cyclandelate?
A:
It is unknown if Cyclandelate affects your ability to drive. Dizziness or light-headedness may occur while taking this medicine and do not drive If you have such symptoms.
Alcohol
Q:
Can I consume alcohol with Cyclandelate?
A:
No data available about the interaction of this medicine with alcohol. But, as Cyclandelate relaxes blood vessels and alcohol also has a relaxing effect on blood vessels, it is advised to drink in low amounts occasionally or to avoid alcohol to prevent increased risk of side effects.
Other General Warnings
Talk to your doctor if
- Serious heart diseases (recent or at risk for heart attack)
- Any conditions (hardened or narrowed arteries) causing impaired blood flow to legs, brain or any blood related or bleeding disorders
- Brain stroke (due to ruptured blood vessels in the brain)
- Increased pressure in the eye (glaucoma)
Mode of Action of Cyclandelate
How Does It Work?
Cyclandelate acts by blocking the calcium inflow into the walls (muscles) of blood vessels and clot formation. Calcium causes contraction and clumping of platelets (clot-forming blood cells), decreased calcium will relax the arteries and veins, thus improving the blood flow....
Interactions of Cyclandelate
Interactions with other medicines
- Avoid:
- Tizanidine (short-acting muscle relaxant)
- Use with caution:
- Medicines for high blood pressure
- Medicines for heart disease
- Anti-clot medicines (Warfarin etc.)
- Inform the doctor about all the medicines you are using (including prescription medicines, non-prescription medicines, and herbal products)
Interactions with food items
It is advised to take the Cyclandelate with food.
Dietary Restrictions of Cyclandelate
Take Cyclandelate with food or substances that reduce acidity of the stomach (antacids such as magnesium or aluminum).
Dosage of Cyclandelate
Overdose
Accidental overdose of Cyclandelate might not be harmful. Consult the doctor in the presence of symptoms of overdose, such as headache, dizziness, weakness or fainting, etc.
Missed a Dose
- If you missed any dose, take it as early as you remember. If it is time for the next dose, skip the missed dose and continue your regular dose schedule. As Cyclandelate is given multiple times in a day, be careful not to take two dosages close to each other. Do not take a higher or a double dose of the medicine to compensate for a missed dose....
Frequently Asked Questions (FAQs)
Q: Is Cyclandelate an effective medicine?
- Cyclandelate reduces or prevents formation of blood clots (clumping of platelets or clot forming blood cells)
- Cyclandelate is also used for prevention of migraine
- Conditions causing poor blood flow to the brain (cerebrovascular diseases)
- Ear problems such as ringing in the ears (tinnitus)
- Though it is difficult to deny that Cyclandelate is an effective medicine that can be used in a variety of conditions, it is not widely used due to a slightly higher risk of side effects
Q: Is there anything else I need to know before taking Cyclandelate?
- Cyclandelate is usually started at high doses, and gradually reduced after the patient shows some response
- It is advised to avoid the use of Cyclandelate in children as no supporting data is available
- Cyclandelate should be taken in the exact dose as prescribed by the physician
- Take medicine along with food or an antacid, to prevent any stomach discomfort
- This medicine is more beneficial when used for long-term
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