Lipoprotein (A) Test
Booked 32 timesAlso known as:
Cholesterol Lp (a) Test, Lp (a) Test
Blood
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Serum
Description
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Overview
Lipoprotein (a) tests help screen cholesterol levels. It is commonly a testing method. Lipoprotein (a) test diagnoses heart health issues before a person finds their signs or symptoms.
The objective of Lipoprotein (a) screening is to discover potential cardiovascular problems early. Therefore, people already suspected of having a high risk of cardiovascular disease are the most likely candidates for screening.
Lipoprotein (a) or Lp (a) testing procedure determines the quantity of a particular lipoprotein (a) particle. The result of the Lipoprotein (a) test is the value of this quantity measured. These lipoprotein particles are present in human blood. Protein and fat combine to form lipoproteins.
As a result, they carry cholesterol through the blood. Hence, the high level of Lipoprotein lp (a) indicates a high cholesterol level in the blood. This raised cholesterol level will relate to an increased risk of heart disease, heart attack and stroke.
The two types or classifications of cholesterol are:
- HDL or Good Cholesterol
- LDL or Bad Cholesterol
Low-Density Lipoprotein cholesterol comes in the form of Lipoprotein (a). LDL cholesterol is also bad cholesterol. Lp(a) levels that are too high might cause plaque to form in the blood vessels. The formation of plaque in the arteries from cholesterol is known as atherosclerosis. Atherosclerosis is a cholesterol accumulation that reduces blood flow via heart arteries.
A high Lipoprotein (a) level shows a person is at risk for heart disease. In addition, it might mean some cholesterol-related conditions, including coronary artery disease. High Lp (a) or Lipoprotein (a) is an independent risk factor for heart disease in studies. However, it's yet unclear how in everyday medicine this information gets used.
Heart disease may occur even if human lipid levels are normal. For instance, in a few cases, a family history of high levels of lp (a) can be a reason to have heart disease. The most common method for predicting the probability of cardiovascular disease is lp (a) testing. It is, however, not a standard sort of cholesterol test. Also, in patients with a higher risk of cardiovascular issues, this testing is commonly done.
People require this test if they have any of the following:
- Heart Disease, despite normal findings on the other lipid tests.
- High cholesterol, besides eating a healthy diet.
- A family history of heart illness, particularly heart disease began at a young age.
Doctors typically test for:
- LDL & HDL
- Total Cholesterol Levels
- Triglycerides, a type of fat detected in blood
They may, however, do a Lipoprotein (a) test to learn more about a person's health. If a person has other heart disease risk factors, the doctor might prescribe the Lipoprotein p(a) test. The test results shall assist in determining the risk. Increased levels of Lipoprotein (a) in the body and inflammation in artery walls are linked. This inflammation can result in blood vessel alterations, such as the hardening of arteries.
Other names of Lipoprotein (a) Test
- Lp (a) Test
- Cholesterol Lp (a) Test
- Cholesterol Lipoprotein (a) Test
- VLDL Cholesterol Test
- HDL Cholesterol Test
What does the Lipoprotein test detect or measure and who is this prescribed for?
A cholesterol test determines the quantity of cholesterol present in LDL particles. The lipoprotein test measures the amount of Lipoprotein (a) particles only and not cholesterol. Lipoprotein is one kind that has emerged as a separate risk factor for vascular disease.
There is substantial evidence linking Lipoprotein Lp (a) levels to cardiovascular risk. Individuals with plasma Lipoprotein Lp (a) levels higher than the usual cut-off level are more likely to develop heart disease. The standard cut-off level is 300 mg/dL.
High levels of Lipoprotein (a) add to the risk of early and severe cardiovascular disease (CVD). Therefore, LipoproteinLp (a) test analyses the risk factor related to the heart.
Cholesterol is a waxy molecule required by the human body for the hormone production and digestion of fats. The human system produces all of the cholesterol it needs. But some foods, such as egg yolks and fatty meats, can also provide cholesterol.
High blood cholesterol levels can cause plaque formation in the arteries. As a result, it can increase heart problems. Because high blood cholesterol has no symptoms, it is critical to test your cholesterol levels. High cholesterol is due to various factors, including health problems, lifestyle and family history. If an individual has risk factors, the doctor might recommend more frequent testing of cholesterol levels.
The conditions for the Lipoprotein (a) test are:
- A history of high blood cholesterol or heart disease in the family.
- Type 2 diabetes.
- Getting older.
- Being a man. Men have greater LDL-C levels and lower HDL-C levels than women without menopause.
- Obesity or being overweight.
- Having had high cholesterol in the past.
As mentioned earlier, the Lipoprotein (a) test is taken based on the demographic age group. Therefore, the doctor might prescribe more frequent measures if the test results aren't within acceptable ranges.
The Lipoprotein (a) test is applicable for children, adults and all other genders. The doctor will suggest for this disease to have a healthy diet and healthy life. Besides that, medications will also help.
Drugs called Statins shall not reduce Lipoprotein (a) levels. However, for lowering heart attack and stroke risk in general, statins are preferred. Niacin, like PCSK9 inhibitors, can reduce Lipoprotein (a) levels by 25-40%. However, the usage of drugs is less frequent.
There are no particular therapies available to reduce lipoprotein levels (a). The genes dictate them. Also, they are unaffected by lifestyle or most medications. However, specific therapies for lowering cholesterol are:
- Stay physically active & exercise regularly
- Choose to eat healthy food
- Completely avoid smoking
- Controlling weight
- Reduce stress
Remember to mention your ongoing or previous medications while consulting the doctor.
Ranges
Less than 30 mg/dL | Normal. No risk |
Greater than 30 mg/dL | High. Increased risk of cardiovascular disease. |
The demographic age group with screening frequency has been mentioned below for reference with risk factors.
Age Group | Risks | Screening Frequency |
Children | No |
Once between 9 to 11 & between 17 to 21.
|
Children | Few or More | 1 to 3 years after detecting the risk. |
Adult of any age | Few or More | Frequently depending on specific risk factors or between 1 to 3 years. |
Male (20-45) Female (20-55) | No | Every 4 to 6 years. |
Male (45-65) Female (55-65) | No | Every 1 to 2 years. |
Seniors above 65 | With/Without Risk | Annually. |
The test depends on a person's lifelong cardiovascular risk. The test prefers frequent cholesterol screenings. It will be only if it's a family disease of early heart attacks or heart disease or if a kid has obesity or diabetes.
How shall I lower my lipoprotein levels naturally?
By making heart-healthy lifestyle modifications. You can include:
- A heart-healthy dietary plan.
- Weight management.
- Common physical factors that naturally lower lipoprotein levels.
Test Result Interpretation
A variety of circumstances and causes may influence the Lipoprotein (a) test results. If individuals taking tests have any of the following conditions, they should not obtain a lipoprotein (a) test:
- Fever
- Recent and Significant Weight Loss
- Infection
- Pregnancy
The risk for heart disease is when the Lipoprotein (a) level is high. This risk is due to increased chances of atherosclerosis. Atherosclerosis is the accumulation of cholesterol as plaque in the arteries. A high lipoprotein (a) result is suggestive of high levels of cholesterol in the blood. Unfortunately, there are no particular therapies available to reduce it.
Genes will direct lipoprotein (a) levels. Also, they are unaffected by lifestyle or most medications. The healthcare provider may offer suggestions to minimize additional risk factors. For example, it might contribute to heart disease if the test results reveal a high level of Lipoprotein (a).
Sample Type
The results of a lipoprotein (a) test depend on the human blood sample analysis. Therefore, tiny blood samples are drawn from the arm. In addition, the laboratory will examine transported blood collected in the tube.
Test Preparation
The Lipoprotein (a) test is a blood test that will not require fasting or any special preparation. However, suppose the doctor has requested additional tests, the individual needs to do fasting.
For example, fasting must be done between nine to twelve hours for a cholesterol test before collecting blood. If there need to be any particular instructions followed, the health care practitioner will inform.
Test inclusions: What are the parameters included?
The Lipoprotein test measures the following parameters which are:
- Lipoprotein (a)
This is the only specific parameter measured by this test. It is a direct marker of the Low-density Lipoprotein (LDL) reported in the Cholesterol test. Lipid profile tests offer a variety of other measurements. The lipoprotein test is focused only on bad cholesterol.
The global burden of cardiovascular disease is often known as coronary heart disease (CHD). It is enormous and rising. Moreover, they are increasing with the majority of people affected living in emerging nations. Diet, diabetes management, amount of physical activity and smoking status are all factors that might influence a person's lipid profile.
How frequently should you take this test?
Checking cholesterol levels is an essential aspect of maintaining human health. Knowing the cholesterol levels might assist in maintaining health management. There are generally no indications or symptoms of high cholesterol.
Getting cholesterol examined is the only method to find out whether an individual has high cholesterol. The age, risk factors and family history influence when and how often you should take a lipoprotein (a) test. The following are some broad suggestions:
For individuals under 19 years or younger with a strong family history:
- Take the first test when a child is between the ages of 9 and 11.
- Every five years, children must retake tests.
- If there are any family histories of heart attack, high blood cholesterol or stroke.
- Some children might undergo this test starting at the age of two.
For individuals at/above the age of 20 with risk factors:
- Repeat this test every five years for younger adults.
- Men between 45 to 65 years should take a test every 1 to 2 years.
- Women between 55 to 65 years should have it every 1 to 2 years.
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Frequently Asked Questions
What does it mean when the Lipoprotein is high?
If the Lipoprotein (a) test is high, it signifies that cholesterol in the blood is increased. Specifically bad cholesterol or LDL. This LDL cholesterol accumulates as plaque in the arteries. The phenomenon of plaque formation is called atherosclerosis. Atherosclerosis is directly linked to an increased risk of heart attacks and heart disease. Thus, the risk of heart disease rises if the Lipoprotein (a) level is high. Unfortunately, there are no particular therapies available to reduce lipoprotein levels (a). Instead, genes will direct lipoprotein (a) levels. Also, they are unaffected by lifestyle or most medications.
How do you reduce Lipoprotein?
One evidence-based strategy for lowering Lp(a) is to start with low-dose aspirin. Also, extended-release niacin was titrated from 0.5 g to 2 g over many weeks. It is highly recommended only with a doctor's guidance.
Can you lower your Lipoprotein A?
Niacin, like PCSK9 inhibitors, can reduce Lipoprotein (a) levels by 25-40%. However, the usage of drugs is less frequent. Instead, try controlling other risk factors for heart disease, such as high blood pressure, diabetes, smoking, drinking, etc.
Can vitamin C lower Lipoprotein A?
A meta-analysis of studies found that vitamin C supplementation reduces Lipoprotein Lp (a). To be specific, vitamin C lowers blood-low-density lipoprotein cholesterol and triglycerides.