Clindamycin+Niacinamide / Nicotinamide

Uses	Acne, whiteheads, blackheads
Therapy	Anti-Acne
Side Effects	Skin irritation, itching, dry skin, burning, redness

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Molecule Description

Clindamycin+Niacinamide / Nicotinamide is an anti-acne medication. It is used to reduce and manage acne, whiteheads, and blackheads. It contains a combination of clindamycin and nicotinamide as its active ingredients. Nicotinamide/niacin is a form of vitamin B3, and clindamycin is an antibiotic. Clindamycin+Niacinamide / Nicotinamide works by reducing the growth and multiplication of acne-causing bacteria. It also helps in lightening the after-marks due to pimples, acne, and other skin problems. Acne is a skin condition that develops when oil and dead skin cells block the hair follicles. It may lead to the development of whiteheads, blackheads, pimples, or acne cysts. Bacteria that live on the skin may further cause inflammation and infection, leading to more severe acne. Acne is more common in teenagers, but anyone can get acne. You may experience a few side effects of Clindamycin+Niacinamide / Nicotinamide such as skin dryness, itching, and burning sensation. Usually, these side effects are temporary and go away with time However, you should report to your doctor if these side effects persist or worsen. Clindamycin+Niacinamide / Nicotinamide is meant only for external application. Do not ingest it. This medicine should be applied exactly as recommended by your doctor. Do not use this medication for treating any other skin conditions without consulting your doctor.

Uses

Clindamycin+Niacinamide / Nicotinamide is used to treat bacterial infection and skin problems such as acne, whiteheads, pimples, and blackheads

Contraindications

When should one not use Clindamycin+Niacinamide / Nicotinamide

If you are allergic to clindamycin, nicotinamide or any other components of Clindamycin+Niacinamide / Nicotinamide.
If you have a history of inflammatory bowel disease
If you have experienced diarrhoea after consuming antibiotics

Side effects

Common side effects of this drug are:

Skin irritation
Itching
Dry skin
Burning
Redness

Precautions and Warnings

Pregnancy

Clindamycin+Niacinamide / Nicotinamide is for topical use, and the quantities which might get absorbed from the skin is too little. The chances of any effect on pregnancy are rare. However, this medicine should be used only under medical supervision. In case you are prescribed with this medicine, avoid using in larger skin areas for a prolonged duration.

Breast Feeding

Consult your doctor before using Clindamycin+Niacinamide / Nicotinamide while breastfeeding. If prescribed, it should not be applied on the breast or areas near the breast in the case of breastfeeding mothers as there can be chances of ingestion of this medicine by a breastfed infant. Avoid using it on large areas of skin or for a prolonged period.

Driving

There is limited information about the effects of Clindamycin+Niacinamide / Nicotinamide on driving, but as it is a topical preparation, it may not affect the driving ability or ability to handle machinery.

Alcohol

There is no direct interaction between Clindamycin+Niacinamide / Nicotinamide and alcohol. However, alcohol is known to worsen the skin infection and inflammation. It's better to avoid consuming alcohol when you are prescribed with this medicine.

Other General Warnings

Talk to your doctor if

You are allergic to any components of this medicine or have a history of any allergic skin reaction.
You are experiencing excessive dryness, irritation, and peeling of the skin.
You have a history of inflammation of the colon or antibiotic-associated diarrhoea.
Avoid contact of this medicine with the eyes, mouth and nose.
Clindamycin+Niacinamide / Nicotinamide is not recommended for use in children below 12 years of age.

Mode of Action

How Does It Work?

Clindamycin is an antibiotic and is widely used to treat various bacterial infections of the skin. It inhibits growth and multiplication of acne-causing bacteria.
Nicotinamide regulates the amount of acne-causing oil being produced by the oil glands in your skin and helps in lightening the after-marks due to pimple, acne, and other skin problems. It also acts as an anti-inflammatory agent and reduces the swelling and redness associated with acne.

Interactions

Interactions with other medicines

There is limited information available on the interaction of Clindamycin+Niacinamide / Nicotinamide with other medicines. However, this medicine contains Clindamycin & Nicotinamide, and any interaction seen with these two components when taken alone may occur with this combination
This medicine is meant for local application on the skin and thus is less likely to interact with other medicines taken orally. However, it may interact with other topically applied creams or gels. Discuss with your doctor if you are already on another topical medication
Be cautious if you are taking oral anticoagulants like Warfarin, Acenocoumarol, and Fluindione, as components of these medicines may interact with Clindamycin+Niacinamide / Nicotinamide. Regular monitoring of blood coagulation parameters is recommended

Dosage

Overdose

Clindamycin+Niacinamide / Nicotinamide is meant to be applied externally on the skin, thus cases of overdose are unlikely.
However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital.
If you have overapplied it, wipe out the excess gel with a clean tissue or cotton.

Missed a Dose

If you have missed applying Clindamycin+Niacinamide / Nicotinamide, apply it as soon as possible. Do not overapply this medicine just to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Wash your face with clean water and pat it dry

Clindamycin is an antibacterial medicine and is not effective against viral infections.

It may help control excess oil production in the skin. Consult your doctor to know whether it suits your skin.

It may help in controlling pimples and lightening the after-marks.

The size of skin pores is usually inherited, and Clindamycin+Niacinamide / Nicotinamide may directly not affect the size of pores. However, Nicotinamide present in this medicine is known to control excessive oil production, which can help in reducing the pore size due to acne and pimples.

The safety and effectiveness of Clindamycin+Niacinamide / Nicotinamide in pediatric patients under the age of 12 have not been established.

Clindamycin+Niacinamide / Nicotinamide is used for treating bacterial infection and skin problems such as acne, whiteheads, pimples, and blackheads

It may help lighten the after-marks left by acne and pimples, but it is not meant for treating dark spots from other causes. Consult your doctor.

It may help control excess oil production in the skin. Consult your doctor to know whether it suits your skin.

Both Clindamycin+Niacinamide / Nicotinamide and Nioclean gel contain a combination of clindamycin and nicotinamide as the main ingredients. It is advised to use the medicine which is prescribed by your doctor and not self medicate.

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