Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone
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Molecule Summary
| Uses | High blood pressure |
| Therapy | Anti-Hypertensive |
| Side Effects | Headache, dizziness, weakness |
Medicines
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19k pincodes
Molecule Description
Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone is a combination of medicines used to treat high blood pressure when a single medication is insufficient for controlling your blood pressure. It contains a combination of telmisartan, cilnidipine, and chlorthalidone (chlortalidone) as active ingredients. While taking this medicine, you should be mindful of your diet and also engage in regular exercise. Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone should be taken as directed by your doctor, in the prescribed doses and duration. Do not stop taking this medicine unless instructed to do so by your doctor. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, as well as about all the medicines and supplements you are taking and any conditions or diseases you have before starting Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone.
Uses
Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone is used for the treatment of high blood pressure, when blood pressure cannot be controlled by telmisartan, cilnidipine or chlorthalidone alone.
Contraindications
When should one not use Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone
- If you are allergic to telmisartan, cilnidipine, chlorthalidone, similar medicines or any of the ingredient of Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone
- If you have severe problems with your liver, kidneys or heart.
- If you feel difficulty in passing urine or passing no urine at all (anuria).
- If you have diabetes or any kidney problem and you are taking medicine for lowering the blood pressure like aliskiren
- If you have a blockage in your gallbladder and small intestine.
- If you have untreated Addison's disease.
- If you are being treated with lithium (used to treat psychiatric illnesses)
- If you are pregnant
Side effects
Common side effects of this drug are:
- Headache
- Dizziness
- Weakness
- Nausea
- Vomiting
- Cough
- Decreased appetite
- Swelling of lower limb
- Low blood pressure that occurs when standing up from sitting or lying down
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any problems with your heart, liver or kidneys
- You are pregnant, think you may be or are planning a pregnancy
- You are diabetic and on aliskiren, an anti-hypertensive medicine to control blood pressure.
- You have increased level of potassium in the blood or are on any potassium supplements
- You have raised aldosterone levels
- You have a history of gout or uric acid stones
- You may experience an increase in the potassium level or sugar level in your blood or elevated uric acid levels.
- You have low levels of potassium or sodium in your blood
- Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone is not recommended for use in patients below 18 years
Mode of Action
How Does It Work?
- Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone works by the combined action of all its components - telmisartan, cilnidipine and chlorthalidone.
- Cilnidipine is a calcium channel blocker, and telmisartan is an angiotensin receptor blocker. Collectively these medicines act by relaxing the blood vessels so that the heart can pump the blood more easily, and it leads to lowering of the blood pressure.
- Chlorthalidone is a diuretic or water pill, it works by increasing the loss of water and salt from the body, thus resulting in increased production of urine, thereby lowering the blood pressure.
Interactions
Interactions with other medicines
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially if you are taking medicines to treat high blood pressure, heart problems, psychiatric illnesses, diabetes, infection, asthma, high cholesterol levels, are taking blood thinners, pain killers, immunomodulatory medicines.
- Medicine used for heart failure like digoxin should be used cautiously.
- You may experience low blood sugar if you are taking medicine for diabetes like insulin, metformin along with this medicine.
- Concomitant use of this medicine along with other blood pressure medicines like aliskiren, anti-cancer medicine like aldesleukin, medicines like aspirin, prednisone, and betamethasone may alter the effects of this medicine.
- Medicines like lithium should be used with caution, as this medicine may increase their levels in the blood.
- Other medicines are quinidine, digoxin, carbamazepine, rifampicin, cimetidine, erythromycin, baclofen, amifostine and water pills like amiloride, spironolactone should be used cautiously.
Dosage
Overdose
- Symptoms of overdose may include dizziness, nausea, sleepiness, electrolyte imbalance, low blood pressure, irregular heartbeats.
- If you think you have taken too much of Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
- If you missed any dose of Telmisartan+Cilnidipine+Chlorthalidone / Chlortalidone, take it as soon as you remember.
- If it is almost time for your next dose, then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Telmisartan 20mg Glenmark Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 2 June 2026]
- Sawant R, Suryawanshi S, Jadhav M, Barkate H, Bhushan S, Rane T. A Prospective, Randomized Open-Label Study for Assessment of Antihypertensive Effect of Telmisartan Versus Cilnidipine Using Ambulatory Blood Pressure Monitoring (START ABPM Study). Cardiol Res. 2023 Jun;14(3):211-220.[cited 2 June 2026]
- Cho EJ, Kim MH, Kim YH, Chang K, Choi DJ, Kang WC, Shin J, Kim SH, Lee N, Son JW, Doh JH, Kim WS, Hong SJ, Rhee MY, Ahn Y, Lim SW, Hong SP, Choi SY, Hyon MS, Hwang JY, Kwon K, Cha KS, Ihm SH, Lee JH, Yoo BS, Kim HS. Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double-blind, active-controlled, multicenter phase 3 trial. J Clin Hypertens (Greenwich). 2023 Sep;25(9):817-827.[cited 2 June 2026]
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