Cilnidipine+Olmesartan Medoxomil

When should one not use Cilnidipine+Olmesartan Medoxomil

• If you are allergic to cilnidipine, olmesartan, or any of the other ingredients of Cilnidipine+Olmesartan Medoxomil.
• If you are being treated with a blood pressure lowering medicine containing aliskiren. If you are not sure what this medicine is, please confirm with your doctor.
• If you are pregnant.
• If you have jaundice (yellowing of the skin and eyes) or problems with the drainage of bile from the gallbladder (biliary obstruction, like gallstones).
• If you have diabetes or kidney problems and are taking a medicine containing aliskiren.

Common side effects of this drug are:

• Headache
• Dizziness
• Tiredness
• Nausea
• Diarrhoea

Other General Warnings

• You are taking medicines like ACE inhibitors (enalapril, lisinopril, ramipril), aliskiren, or diuretics (water tablets).
• You have kidney or liver problems.
• You have heart failure or problems with your heart valves or heart muscle.
• You have severe vomiting or diarrhoea.
• You are on a low salt diet.
• You have problems with your adrenal glands.
• You experience diarrhoea that is severe, persistent and causes substantial weight loss after using this medicine.
• You think you are pregnant, might become pregnant, or are breastfeeding.
• You have low blood pressure.

How Does It Work?

• Cilnidipine+Olmesartan Medoxomil contains a combination of cilnidipine and olmesartan as active substances.
• Cilnidipine is a calcium channel blocker that blocks the incoming calcium and prevents the contraction of blood vessels. This helps to reduce blood pressure.
• Olmesartan blocks all the actions of a chemical called angiotensin II which helps to relax the blood vessels and thereby lowers blood pressure.

Interactions with other medicines

• Some medicines can affect the way Cilnidipine+Olmesartan Medoxomil works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Inform your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• The effect of Cilnidipine+Olmesartan Medoxomil may be increased when taken along with other blood pressure lowering medicines.
• Do not take this medicine if you are taking an ACE inhibitor like captopril or aliskiren (used to lower high blood pressure).
• The levels of potassium in your blood may be increased when potassium supplements, salt substitutes that contain potassium, water tablets (diuretics), or heparin (used for thinning
• the blood) is used along with this medicine.
• Lithium (used to treat mood swings and some mental disorders) used at the same time as Cilnidipine+Olmesartan Medoxomil may increase the toxicity of lithium.
• Non-steroidal anti-inflammatory medicines (used to relieve pain, swelling, and inflammation) used along with Cilnidipine+Olmesartan Medoxomil may increase the risk of kidney failure.
• Particular care should be taken if you are taking colesevelam (used to lower the level of cholesterol in your blood), certain antacids (used to treat indigestion), aldesleukin (used to treat advanced kidney cancer), quinidine (used for treating abnormal/irregular heartbeats), phenytoin (used to treat fits/seizures), rifampicin (used to treat tuberculosis), erythromycin (used for the treatment of bacterial infections), and anti-psychotic medicines (used to treat mental disorders).

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