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Chlorpheniramine Maleate+Phenylepherine

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Molecule Description

Chlorpheniramine maleate+Phenylephrine is a combination medicine. It is used for temporary relief in common cold and allergic rhinitis. It helps in improving symptoms like runny and stuffed nose, sneezing and throat irritation. Chlorpheniramine is an antiallergic and phenylephrine is a decongestant. Chlorpheniramine maleate+Phenylephrine is available in the form of a tablet, capsule, syrup, suspension, oral drops and oral liquid. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.

Uses

Chlorpheniramine maleate+Phenylephrine is used for the symptomatic treatment of common cold and allergic rhinitis.

Contraindications

When should one not use Chlorpheniramine Maleate+Phenylepherine

  • If you are allergic to chlorpheniramine, phenylephrine or similar medicines.
  • If you suffer from any heart diseases like high blood pressure.
  • If you have taken medicines for brain disorders such as rasagiline in the last 14 days.
  • If you have diabetes or increased pressure inside the eyes (glaucoma).
  • If you experience difficulty in urination due to an enlarged prostate gland.
  • If you are suffering from an overactive thyroid gland and breathing problems like bronchitis.

Side effects

Common side effects of this drug are:

  • Headache
  • Drowsiness
  • Dizziness
  • Vomiting
  • Weakness

Precautions and Warnings

Pregnancy

Pregnancy

Chlorpheniramine maleate+Phenylephrine should be used during pregnancy only if considered essential by the doctor after assessing the benefits over risks.

Breast Feeding

Breast Feeding

Consult your doctor before using chlorpheniramine maleate+phenylephrine while breastfeeding as it passes into breast milk.

Driving

Driving

Be cautious while driving as chlorpheniramine maleate+phenylephrine may make you feel dizzy or drowsy.

Alcohol

Alcohol

Avoid consuming alcohol with chlorpheniramine maleate+phenylephrine as it may worsen the side effects.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have kidney or liver disease.
  • You are already taking medicines for psychiatric illness.
  • You have a blockage in your stomach and intestine.
  • You have a history of fits or seizures.
  • You have asthma or any airway obstruction problems.
  • You are pregnant or breastfeeding.
  • You have a history of tumours in the adrenal gland.
  • You experience drowsiness or nervousness.

Mode of Action

How Does It Work?

  • Chlorpheniramine acts by blocking the action of histamine a natural substance produced by the body during an allergic reaction and improves allergic symptoms like sneezing, watery eyes, throat irritation.
  • Phenylephrine acts as a vasoconstrictor, it shrinks or constricts the blood vessels in the nasal passage and improves congestion.

Interactions

Interactions with other medicines

  • Some medicines can affect the way chlorpheniramine maleate+phenylephrine works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Medicines used to treat brain disorders or psychiatric illness should not be used with Chlorpheniramine maleate+Phenylephrine as it can lead to a risk of heart-related side effects or increased blood pressure.
  • This medicine can reduce the effectiveness of high blood pressure medicines and can increase blood pressure abruptly.
  • It should not be taken along with medicines used to treat heart failures such as digoxin as it can increase the risk of irregular heartbeat or heart attack.
  • Phenytoin and ergot containing medicines should not be consumed along with Chlorpheniramine maleate+Phenylephrine as it can lead to toxicity.
  • Other medicines like medicines to induce sleep or anti-anxiety medicines and ceratin painkillers should be used as they can induce sedation.

Frequently Asked Questions (FAQs)

Chlorpheniramine maleate+Phenylephrine is used for relieving common cold and allergic rhinitis with the symptoms of throat pain, sneezing, runny or stuffed nose.

Chlorpheniramine maleate+Phenylephrine is available in the form of a tablet, capsule, syrup, suspension, oral drops and oral liquid.

Yes, Chlorpheniramine may cause drowsiness or sleepiness, while Phenylephrine may cause slight restlessness in some people. Avoid driving, using machines, or doing tasks that need alertness until you know how the medicine affects you. If drowsiness becomes excessive or troublesome, consult your doctor for guidance. Alcohol can increase drowsiness, so it’s best to avoid it. Always follow your doctor’s recommended dose.

Many cold medicines contain similar ingredients, so combining them may lead to overdosage or unwanted side effects. Always inform your doctor about all medicines you are taking.

Phenylephrine may increase blood pressure. It is important to inform your doctor if you have high BP, heart disease, or thyroid issues before taking this medicine. Your doctor will decide if it is safe for you or suggest an alternative. Do not self-medicate based on symptoms alone.

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