Chlorpheniramine / Chlorphenamine+Pseudoephedrine+Paracetamol / Acetaminophen
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Molecule Summary
| Uses | Treatment of symptoms of common cold and allergic rhinitis |
| Therapy | Cough Cold Preparation |
| Side Effects | Sleepiness, dizziness, dry mouth, nausea, vomiting, headache, drowsiness, blurred vision, constipation |
Medicines
available
19k pincodes
Molecule Description
Chlorpheniramine / Chlorphenamine+Pseudoephedrine+Paracetamol / Acetaminophen is a prescription medication. It is used to treat symptoms of a common cold like running nose, nasal congestion, and sneezing. It is a combination of three active components, Chlorpheniramine, Pseudoephedrine and Paracetamol.
Uses
- Chlorpheniramine / Chlorphenamine+Pseudoephedrine+Paracetamol / Acetaminophen is used in the treatment of symptoms of common cold and allergic rhinitis
Contraindications
When should one not use Chlorpheniramine / Chlorphenamine+Pseudoephedrine+Paracetamol / Acetaminophen
- It is contraindicated in patients with hypersensitivity to Chlorpheniramine, Pseudoephedrine, Paracetamol, or any other components in this medicine.
- It is contraindicated in patients with asthma and sleep apnea.
- This medication is contraindicated in pregnancy and lactation.
Side effects
Common side effects of this drug are:
- Sedation
- Dizziness
- Dry mouth
- Nausea
- Vomiting
- Constipation
- Blurring of vision
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Inform your doctor if you are using any medications at the time of prescription of this medicine.
- You have cardiac arrhythmias or heart disease.
- You have high blood pressure.
- You have glaucoma.
- You have difficulty passing urine (urinary retention).
- You have liver or kidney problems.
Mode of Action
How Does It Work?
Chlorpheniramine is a first-generation antihistamine. Histamines are chemical messengers present in blood that are indicated in allergic responses. Chlorpheniramine blocks Histamine receptors.
Interactions
Interactions with other medicines
- Concomitant use with hypnotics and anti-anxiety medicines can cause an increase in sedation.
- Concomitant use with alcohol and other CNS depressants can worsen neurological side effects.
- Chlorpheniramine decreases the metabolism of phenytoin and can result in phenytoin toxicity.
- Side effects of Chlorpheniramine like dry mouth, constipation and other effects like urinary retention and increased intraocular pressure can occur when used concomitantly with MAOIs (monoamine oxidase inhibitors) like Selegiline and Rasagiline.
Interactions with food items
- This medication does not have any known interactions with food items.
Dosage
Overdose
Overdose can present with symptoms like euphoria, dizziness, increased sedation, delirium, decreased coordination, heart rhythm abnormalities, increase in BP, and decreased heart rate.
Missed a Dose
If you miss a dose of this medicine, it is advised to take it as soon as possible. If the duration lapsed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose and go back to the regular schedule. Do not double the dose.
Frequently Asked Questions (FAQs)
Articles
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References:
- Farzam K, Sabir S, O'Rourke MC. Antihistamines. [Updated 2021 Dec 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-
- Richards E, Lopez MJ, Maani CV. Phenylephrine. [Updated 2021 Jul 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-
- National Centre for Biotechnology Information. PubChem Compound Summary for CID 5281068, Chlorpheniramine maleate.
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