Cefuroxime+Potassium Clavulanate(Clavulanic Acid)
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Molecule Summary
| Uses | Bacterial infections |
| Therapy | Antibiotic |
| Side Effects | Diarrhoea, nausea, vomiting, stomach pain, headache |
Medicines
available
19k pincodes
Molecule Description
Cefuroxime+Potassium Clavulanate(Clavulanic Acid) is an antibiotic medicine and is used to treat various bacterial infections like infections of the urinary tract, respiratory tract and sexually transmitted diseases. It contains cefuroxime and clavulanic acid as its active components. Cefuroxime is a cephalosporin antibiotic that acts by inhibiting the cell wall synthesis of bacteria. Clavulanic acid acts by inhibiting the enzyme made by bacteria; this will help cefuroxime to function optimally. Cefuroxime+Potassium Clavulanate(Clavulanic Acid) should be taken as directed by the doctor and in the correct dose and for the exact duration as prescribed. Take this medicine with food, at the same time daily, for a better outcome. Do not stop taking this medicine even if you start feeling better after starting the treatment with Cefuroxime+Potassium Clavulanate(Clavulanic Acid).
Uses
Cefuroxime+Potassium Clavulanate(Clavulanic Acid) is used to treat various types of bacterial infections in the body of the urinary tract, respiratory tract and sexually transmitted diseases like gonorrhoea.
Contraindications
When should one not use Cefuroxime+Potassium Clavulanate(Clavulanic Acid)
- If you are allergic to cefuroxime or clavulanic acid or any of the ingredients of Cefuroxime+Potassium Clavulanate(Clavulanic Acid).
- If you have a history of a severe allergy to any other antibiotics like penicillins.
Side effects
Common side effects of this drug are:
- Diarrhoea
- Nausea
- Vomiting
- Stomach pain
- Headache
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a history of an allergy to any antibiotic like cephalosporins, penicillins.
- You are already taking water pills, as it can affect kidney functions.
- You have a history of pain and swelling in the inner lining of the intestine.
Mode of Action
How Does It Work?
Cefuroxime acts by inhibiting the cell wall synthesis of bacteria, which is responsible for bacterial infection. However, bacteria make an enzyme (beta-lactamases), which can destroy cefuroxime. Clavulanic acid inactivates this enzyme and hence helps cefuroxime to function optimally.
Interactions
Interactions with other medicines
- Cefuroxime+Potassium Clavulanate(Clavulanic Acid) may interact with other medicines and produce an altered response. Please tell your doctor if you are using any other medicines, over-the-counter medicines (that you buy without a prescription), and herbal preparations.
- There is limited information available on the interaction of this combination with other medicines. However, any interactions seen with these two components, when taken alone, may occur with this combination.
- Oral contraceptives, antacids and medicines used in the treatment of gout, such as Probenecid, should be used cautiously.
Interactions with food items
It is recommended to take Cefuroxime+Potassium Clavulanate(Clavulanic Acid) with food to enhance absorption and minimize gastrointestinal discomfort.
Dosage
Overdose
- Symptoms of an overdose include brain damage, fits or coma. If you think you have taken an excessive dose of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
- It is advised not to miss any dose of antibiotics as it can fail the therapy.
- If you have missed any dose of Cefuroxime+Potassium Clavulanate(Clavulanic Acid), take it as soon as you remember.
- If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
- Do not take a double dose of medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Cefuroxime 250mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 13 June 2026]
- Manjula S, and Krishna Kumar M. 2024. "Assessment of Cefuroxime and Cefuroxime Clavulanic Acid Prescription Practices for Infection Management in Routine Indian Healthcare Settings: Expert Insights" [cited 13 Jun 2026]
- Brambilla C, Kastanakis S, Knight S, Cunningham K. Cefuroxime and cefuroxime axetil versus amoxicillin plus clavulanic acid in the treatment of lower respiratory tract infections. Eur J Clin Microbiol Infect Dis. 1992 Feb;11(2):118-24 [cited 13 Jun 2026]
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