Ceftriaxone is used to treat various bacterial infections such as infection of
the brain, lungs, ear, stomach, urinary tract, joints, blood, skin and soft tissues. It works killing the infection-causing bacteria. Ceftriaxone belongs to a group of medicine called an antibiotic. It is available in the form of tablet, syrup, injection and dry syrup. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting ceftriaxone.
Uses of Ceftriaxone
Ceftriaxone is used for the treatment of bacterial infection of the brain, lungs, airways, stomach, urinary tract, bone, joints, blood, skin and soft tissues.
Contraindications of Ceftriaxone
When should one not use Ceftriaxone
- If you are allergic to ceftriaxone or similar medicines like antibiotics from class cephalosporin, penicillins, monobactams and carbapenems.
- It should not be used in premature babies, newborns suffering from jaundice or receiving calcium intravenously.
Side effects of Ceftriaxone
Common side effects of this drug are:
- Skin rashes
- Irregular blood cell count
- Injection site pain
Precautions and Warnings of Ceftriaxone
Can I take Ceftriaxone during pregnancy?
Ceftriaxone should be taken during pregnancy only if considered essential by the doctor and potential risks justify the benefits.
Can I take Ceftriaxone while breastfeeding?
Consult a doctor before using Ceftriaxone while breastfeeding as it passes into breast milk in small quantities. However, the baby should be closely monitored for the side effects such as diarrhoea, thrush or fungal infection of the mouth.
Can I drive if I have taken Seftriaxone?
Ceftriaxone may cause dizziness, thus you need to be cautious while driving.
Can I consume alcohol with Ceftriaxone?
Avoid consuming alcohol with Ceftriaxone, as it may worsen the side effects.
Other General Warnings
Talk to your doctor if
- You have problems with your kidney or liver.
- You have stomach disease or you have experienced diarrhoea after taking antibiotics.
- You have inflammation or swelling in any part of your bowel.
- You are suffering from gallstones (stones in the gallbladder), anaemia (decreased red blood cells).
- You have taken any medicine or supplement containing calcium recently.
- You are on a low sodium diet.
- Before using ceftriaxone in children, let the doctor know if your child has been given a product containing calcium into their vein.
- Let the doctor or the laboratory person know that you are using Ceftriaxone while going for a lab test, as it may interfere with the lab tests.
Mode of Action of Ceftriaxone
How Does It Work?
Ceftriaxone works by stopping the formation of the cell wall of the bacteria and thus killing the bacteria which causes infection.
Interactions of Ceftriaxone
Interactions with other medicines
- Some medicines can affect the way ceftriaxone works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
- Especially, if you are taking medicines to treat your high blood pressure, heart problems, high/abnormal cholesterol levels or are taking blood thinners, anti-infectives, anti-diabetics, anti-asthmatics, pain killers, immunomodulatory medicines or medicines for brain-related disorders....
- Blood thinners can increase the risk of bleeding. Hence, inform your doctor about it.
Dr. Mansi Savla
B. Pharm, PharmD
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: In which all dosage forms is Ceftriaxone available?
A: Ceftriaxone is available in the form of tablet, syrup, injection and dry syrup.
Q: Does Ceftriaxone cause diarrhoea?
A: Ceftriaxone may cause diarrhoea as a side effect.
- Rocephin 1g Powder for Solution for Injection or Infusion [Internet]. Accessdata.fda.gov. 2021 [cited 22 November 2021]
- CDSCO - Ceftriaxone injection [Internet]. Cdscoonline.gov.in. 2021 [cited 22 November 2021]
- CEFBACT Injection [Internet]. CiplaMed. 2021 [cited 22 November 2021]
- Ceftriaxone [Internet]. Ncbi.nlm.nih.gov. 2021 [cited 22 November 2021]
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