Ceftriaxone
Description
Ceftriaxone is an antibiotic used to treat a wide range of bacterial infections
, including those affecting the brain, lungs, ears, stomach, urinary tract, joints, blood, skin, and soft tissues. It works by killing the bacteria that cause these infections, helping you recover faster and preventing the disease from spreading. Depending on your condition, it may be given as an injection, tablet, syrup, or dry syrup, and your doctor will choose the most suitable form and dose for you. Before starting Ceftriaxone, it is essential to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. You should also share details about any other medicines, supplements, or herbal products you are taking, as well as any existing health conditions. This helps your doctor ensure the treatment is safe and effective for you, and reduces the risk of side effects or interactions.
Uses
Contraindications
When should one not use Ceftriaxone
- If you are allergic to ceftriaxone or similar medicines like antibiotics from class cephalosporin, penicillins, monobactams and carbapenems.
- It should not be used in premature babies, newborns suffering from jaundice or receiving calcium intravenously.
Side effects
Common side effects of this drug are:
- Diarrhoea
- Skin rashes
- Irregular blood cell count
- Injection site pain
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have problems with your kidney or liver.
- You have stomach disease or you have experienced diarrhoea after taking antibiotics.
- You have inflammation or swelling in any part of your bowel.
- You are suffering from gallstones (stones in the gallbladder), anaemia (decreased red blood cells).
- You have taken any medicine or supplement containing calcium recently.
- You are on a low sodium diet.
- Before using ceftriaxone in children, let the doctor know if your child has been given a product containing calcium into their vein.
- Let the doctor or the laboratory person know that you are using Ceftriaxone while going for a lab test, as it may interfere with the lab tests.
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Some medicines can affect the way ceftriaxone works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
- Especially, if you are taking medicines to treat your high blood pressure, heart problems, high/abnormal cholesterol levels or are taking blood thinners, anti-infectives, anti-diabetics, anti-asthmatics, pain killers, immunomodulatory medicines or medicines for brain-related disorders....
- Blood thinners can increase the risk of bleeding. Hence, inform your doctor about it.
Content Details
Dr. Mansi Savla
B. Pharm, PharmD
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: In which all dosage forms is Ceftriaxone available?
Q: Does Ceftriaxone cause diarrhoea?
References
- Rocephin 1g Powder for Solution for Injection or Infusion [Internet]. Accessdata.fda.gov. 2021 [cited 18 November 2025]
- CDSCO - Ceftriaxone injection [Internet]. Cdscoonline.gov.in. 2021 [cited 18 November 2025]
- CEFBACT Injection [Internet]. CiplaMed. 2021 [cited 18 November 2025]
- Ceftriaxone [Internet]. Ncbi.nlm.nih.gov. 2021 [cited 18 November 2025]









