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Carvedilol

Molecule Description

Carvedilol is a Cardiovascular medicine used to treat high blood pressure and chest pain due to reduced blood flow to the heart caused by the narrowing of arteries (blood vessels). It belongs to a class of medicines called ‘beta-blockers.’
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Uses of Carvedilol

Treatment of high blood pressure with no known cause (essential hypertension), chest pain while walking or any activity which has a definite pattern (chronic stable angina). Add-on treatment for prolonged standing heart failure (moderate to severe chronic heart failure).
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Contraindications of Carvedilol

When should one not use Carvedilol

  • Allergy to Carvedilol or any components of the medicine
  • History of asthma or other lung diseases
  • If you are suffering from any heart or liver problem
  • If you are suffering from severe disturbances in the body’s acid-base balance (metabolic acidosis)

Side effects of Carvedilol

Common side effects of this drug are:

  • Dizziness, low blood pressure, headache, tiredness
  • Heart failure (inadequacy of the heart to pump blood efficiently)
  • Lung problems, urinary infections
  • Decreased red blood cells
  • Weight gain
  • Poorly controlled blood sugar and cholesterol levels
  • Visual problems, dry eyes
  • Slow heart rate, swelling of hands and feet (edema)
  • Breathing problems, blood circulation problems (coldness and pain of hands and legs)
  • Breathing problems, asthma
  • Loose motions, stomach pain, indigestion, discomfort
  • Kidney problems, difficult to urinate
  • Sleep disturbances, confusion, chest pain, abnormal sensations, allergic skin reactions (itching, rashes, redness), hair loss, impotence, fainting (uncommon)
  • Low platelets, dry mouth, stuffy nose (rare)

Precautions and Warnings of Carvedilol

Pregnancy

Q:
Can I take Carvedilol during pregnancy?
A:
Adequate data is not available, and it is unknown if Carvedilol can be harmful for the baby. Hence, it is recommended to avoid this medicine during pregnancy unless other alternatives are not available.

Breast Feeding

Q:
Can I take Carvedilol while breastfeeding?
A:
Carvedilol secretes in the breast milk, and it has the potential to harm the baby. Hence women taking this medicine should not breast-feed.

Driving

Q:
Can I drive if I have consumed Carvedilol?
A:
Carvedilol is not known to affect your ability to drive but you can experience drowsiness and reduced alertness. Hence, caution is recommended.

Alcohol

Q:
Can I consume alcohol with Carvedilol?
A:
Avoid drinking alcohol as some side effects of Carvedilol may be worsened with alcohol.

Other General Warnings

Talk to your doctor if
  • Heart, liver, kidney, or thyroid problems
  • Diabetes, poor circulation affecting feet, hands, lower legs (Raynaud phenomenon)
  • Allergic reactions for which you have taken treatment
  • Wearing contact lenses (as Carvedilol can cause drying of eyes)

Mode of Action of Carvedilol

How Does It Work?

It relaxes and widens the blood vessels and makes it easier for your heart to pump blood throughout the body. Hence, it reduces blood pressure and strain on your heart.

Interactions of Carvedilol

Interactions with other medicines

  • Medicines used for irregular heartbeats (Diltiazem, Verapamil, Amiodarone)
  • Medicines for chest pain and heart failure (Isosorbide Mononitrate or Glyceryl Trinitrate, Digoxin)
  • Antihyperstensives (Doxazosin, Amlodipine, Reserpine, Indoramin)
  • Antidepressants (Fluoxetine, Amitryptiline, Imipramine, etc.)
  • Immunosuppressants (Cyclosporine, Prednisolone)
  • Painkillers, Ergot medicines (to treat migraine)
  • Antibiotics (Rifampicin, Erythromycin)
  • Antifungals (Ketoconazole etc.)
  • Medicines for cough and cold (Ephedrine, Pseudoephedrine)

Interactions with food items

Take the tablet with a meal or right after a meal along with a glass of water.

Dosage of Carvedilol

Overdose

Unintentional overdose may not be life-threatening. But,a high overdose can be harmful. If you experience symptoms such as low blood pressure, slow heart rate, chest pain, difficulty in breathing or any disturbed consciousness then seek medical attention without delay.
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Missed a Dose

It is ideal not to miss a dose. If you remember a missed dosage, take it instantly. However, if it is almost time for the next dose, skip the missed dose and continue as per your regular dosage schedule. Do not take a higher dose or a double dose to compensate for the missed dose.
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Content Details

WRITTEN BY
doctor

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

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Q: What else should I know before beginning the medication of Carvedilol?

A: When a patient has begun the medication on Carvedilol or in the first few days after increasing a dose, it may worsen the symptoms, especially in the person has had or is having a heart failure or is taking water pills (tablets that cause excess urination). This is not a cause of concern and the dose should not be increased. Do not self-medicate with Carvedilol. This medicine should not be stopped abruptly. The dose has to be decreased gradually by your doctor, and its adjustments must be done under medical supervision. Kidney function, platelet counts and blood glucose are needed regularly. Carvedilol should not be consumed by children and adolescents under 18 years of age. Always take this medicine with food.

Q: Is Carvedilol better than other medicines to treat high blood pressure and chest pain?

A: Carvedilol is one of the best medicines for your heart. It has fewer side effects than other medicines of its class (beta-blockers). Carvedilol is associated with the efficient heart functioning. It has a minimal impact on the heart rate and heart beats and can effectively control the blood pressure. This medicine is also beneficial for patients with diabetes and high cholesterol. Carvedilol reduces blood clot formation and frequency of heart attacks and is sometimes given in patients after a heart attack to prevent further complications.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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