Ampicillin+Cloxacillin
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Molecule Summary
| Uses | Bacterial infection |
| Therapy | Antibiotic |
| Side Effects | Diarrhoea, nausea, vomiting, skin rash, urge to scratch |
Medicines
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Molecule Description
Ampicillin+Cloxacillin is an antibiotic medicine. It is used to treat various bacterial infections of the lungs, throat, airways, skin, soft tissues, bones, ears, noses, and wounds after surgery caused by various organisms. Ampicillin+Cloxacillin contains ampicillin and cloxacillin as its active ingredients. It belongs to the 'Penicillin' class of antibiotics.
Ampicillin+Cloxacillin acts by inhibiting growth and killing the bacteria that cause infection. Take this medicine as prescribed by your doctor for the exact prescribed duration. Do not stop taking the medicine, even if you feel better, as incomplete treatment may result in treatment failure and the infection might recur.
Before using Ampicillin+Cloxacillin, inform the doctor if you are pregnant, planning a pregnancy, or breastfeeding, and provide your detailed medical history.
Uses
- Ampicillin+Cloxacillin is used to treat bacterial infections of lungs, throat, airways, skin & soft tissue, bone, ear, nose, blood and other bacterial infections.
- It is also used to treat infection of wounds and lungs after surgery.
Contraindications
When should one not use Ampicillin+Cloxacillin
- If you are allergic to ampicillin, cloxacillin or any of the ingredient of Ampicillin+Cloxacillin.
- If you are allergic to similar antibiotics like Cefixime, Cefpodoxime, Amoxicillin.
- Ampicillin+Cloxacillin should never be used for eye infections and eye contact should be avoided.
Side effects
Common side effects of this drug are:
- Nausea
- Skin rashes
- Urge to scratch
- Diarrhoea
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a history of allergy to Penicillins.
- You experience serious allergic reactions and skin rashes after taking this medicine.
- You are having watery diarrhoea or severe stomach pain, immediately stop this medicine and consult your doctor.
- You develop other infections while taking this medicine.
- You have existing kidney problems.
- You should not give this medicine to newborn babies suffering from jaundice.
- It is advised to complete the course of antibiotics and not skip any dose even if you feel better.
Mode of Action
How Does It Work?
Ampicillin+Cloxacillin inhibits the formation of the bacterial cell wall and kills the bacteria responsible for the infection.
Interactions
Interactions with other medicines
- Sometimes Ampicillin+Cloxacillin may affect the way other medicines work, and other medicines may affect how Ampicillin+Cloxacillin works if taken at the same time.
- Always inform your doctor about all the medicine you are taking, that includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatments you are taking for any disorder.
- In particular, if you are taking medicines for gout, antibiotics like chloramphenicol, azithromycin, painkillers etc.
- This medicine hampers how the oral contraceptive medication works. Thus, it is advised to use alternative physical contraceptive measures like condoms.
Interactions with food items
Ampicillin+Cloxacillin should ideally be taken on an empty stomach, either 1 hour before or 2 hours after meals, to ensure optimal absorption and effectiveness.
Dosage
Overdose
The overdose of Ampicillin+Cloxacillin may cause serious kidney failure if you have existing kidney problems. Symptoms of overdose are nausea, vomiting and diarrhoea. If you think you have taken too many doses of the medicine than prescribed, inform your doctor immediately or reach the nearest hospital.
Missed a Dose
If you have missed or have forgotten to take a single dose of the medicine, take it as soon as you remember. However, if it's time for your next dose, skip the forgotten dose and continue with a regular dose schedule. Do not take a double dose of the medicine to compensate for the missed one.
Frequently Asked Questions (FAQs)
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References:
- Peechakara BV, Basit H, Gupta M. Ampicillin. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. [cited 2026 Jun 12].
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 6249, Ampicillin. Retrieved January 15, 2025
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 6098, Cloxacillin. Retrieved January 15, 2025
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