Amisulpride
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Molecule Summary
| Uses | Schizophrenia |
| Therapy | Anti-Psychotics |
| Side Effects | Nausea, Dizziness, Blurred vision, Constipation, Increased saliva secretion, Weight gain, Tremors |
Medicines
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19k pincodes
Molecule Description
Amisulpride is used for the treatment of schizophrenia. Schizophrenia is a mental health condition characterised by hallucinations, delusions, extremely disordered thinking and behaviour, impairing daily functioning and disabling. Amisulpride helps stabilise symptoms like irritability, anxiety, and other behaviours in people suffering from schizophrenia.
Uses
- As per CDSCO, Amisulpride is used in the treatment of acute and chronic schizophrenic disorders.
Contraindications
When should one not use Amisulpride
- If you are allergic to components of Amisulpride.
- If you are already on other antipsychotic medication.
- If you are taking anti-Parkinson's medicine Levodopa.
- If you have breast cancer or a family history of breast cancer. This medicine can increase prolactin (hormone) levels in the body.
- If you have Parkinson's disease or dementia.
- If you have an adrenal gland tumour, this medicine can cause life-threatening high blood pressure.
- If you are pregnant or planning for it.
Side effects
Common side effects of this drug are:
- Nausea
- Dizziness
- Blurred vision
- Constipation
- Increased saliva secretion
- Weight gain
- Tremors
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any allergic reactions after taking Amisulpride.
- You have any suicidal ideation or self-harming thoughts.
- You experience severe changes in thought, behaviour or mood.
- You notice a sudden decrease or loss of vision.
- Your symptoms do not improve, or there is worsening of your condition.
- You have a history of mild or severe liver or kidney conditions; this medicine may need a dose adjustment.
- You have withdrawal symptoms like agitation, nausea, tremor, sweating and confusion.
- You are using any ayurvedic or herbal medicines, vitamins and other health supplements.
- You have respiratory issues.
Mode of Action
How Does It Work?
It acts by increasing dopamine and serotonin activity by blocking their receptors. These are chemical substances responsible for mood, ability, and cognitive behaviour. By blocking these receptors, the effect of these substances lasts longer, which helps in improving the various symptoms of psychological and mental disorders.
Interactions
Interactions with other medicines
- Anxiety meds, such as diazepam, clonazepam, chlordiazepoxide, alprazolam and lorazepam. You may experience sedation and drowsiness.
- Blood pressure-lowering medicine, such as amlodipine, lisinopril, losartan, or metoprolol. You may have low blood pressure.
- Pain killers, such as morphine, oxycodone, fentanyl, hydrocodone, tramadol, and codeine. Interaction may cause more sedation and drowsiness.
- Anti-Parkinson medicines such as levodopa. Taking this medicine with Levodopa for Parkinson's disease is not recommended, as they have exactly opposite effects.
- Interaction with Antifungal medications like itraconazole and ketoconazole can reduce its effects.
- Interaction with Antidepressants or mood-elevating medicines like fluoxetine and desipramine can cause increased side effects.
- Interaction with other sedatives, heart medicines, antimalarial medicines, antihistamines, etc. All these medications can cause interactions.
Interactions with food items
- You can continue with the regular diet as food doesn't influence the effect of Amisulpride.
Dosage
Overdose
An overdose of Amisulpride can cause dizziness, agitation, confusion, tremors, convulsion, nausea, vomiting, sleep disturbances, hypotension, increased heart rate, diminished reflexes, and coma. If you experience any of these symptoms or overdose on this medicine, immediately seek emergency medical treatment from a nearby hospital.
Missed a Dose
If you've missed a dose of Amisulpride, take it as soon as possible. If you remember missing a dose when it's already time to take the next scheduled dose, then skip the missed dose and take the next scheduled dose. Talk to your doctor if you have any confusion regarding this issue. Do not take both doses together as it can cause overdose side effects.
Frequently Asked Questions (FAQs)
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