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Amiloride+Frusemide / Furosemide

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Molecule Summary

Uses
Hypertension, oedema
Therapy
Anti-Hypertensive
Side Effects
Nausea, headache, dizziness, dehydration, rashes
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Molecule Description

Amiloride+Frusemide / Furosemide is a blood pressure-lowering medicine that is used to treat high blood pressure. It is also used to stop the buildup of extra water in your body. High blood pressure is a condition where the force with which your blood pushes against the walls of your blood vessels is continuously too high. This may increase the risk for medical problems like heart disease, heart attack, or stroke. Amiloride+Frusemide / Furosemide contains a combination of amiloride and furosemide as active substances that work by removing the extra strain on the heart and blood vessels. Amiloride+Frusemide / Furosemide is to be used only in adults aged 18 years and above. Always take this medicine in the exact dose and duration as recommended by your doctor. Do not take this medicine on your own.

Uses

  • Amiloride+Frusemide / Furosemide is used for the treatment of oedema and high blood pressure in adults.

Contraindications

When should one not use Amiloride+Frusemide / Furosemide

  • If you are allergic to amiloride, furosemide, or any other ingredient of Amiloride+Frusemide / Furosemide.
  • If you are allergic to sulfonamide or sulfonamide derivatives, like sulfamethoxazole. If you are not sure what these medicines are, please confirm with your doctor.
  • If you have severe liver or kidney problems.
  • If you are dehydrated, have a low blood volume, or are not passing any urine.
  • If you have too little or too much potassium or sodium in your blood or are taking medicines that may change the amount of potassium in your blood.
  • If you have a disease called Addison's disease.
  • If you are under 18 years of age.

Side effects

Common side effects of this drug are:

  • Nausea
  • Headache
  • Dizziness
  • Dehydration
  • Rashes

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information about the effect of Amiloride+Frusemide / Furosemide in pregnant women. Thus, it is recommended not to use Amiloride+Frusemide / Furosemide in pregnancy unless recommended by the doctor.

Breast Feeding

Breast Feeding

Amiloride+Frusemide / Furosemide may pass into human breast milk. This medicine should not be used in women who are breastfeeding.

Driving

Driving

Limited information is known about the effect of Amiloride+Frusemide / Furosemide on driving ability. After taking this medicine if you experience any symptoms which may alter your consciousness, then it is suggested that you do not drive.

Alcohol

Alcohol

There is limited information available on the interaction of Amiloride+Frusemide / Furosemide with alcohol. Please consult your doctor regarding the intake of alcohol with Amiloride+Frusemide / Furosemide.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are going to have a glucose test.
  • You have gout, diabetes, liver, or kidney problems.
  • You have blockage of the urinary tract or difficulty in passing urine.
  • You are 65 years of age or older.
  • You have low blood pressure or low blood volume.
  • You have lower than normal protein levels.
  • You are an elderly patient with dementia and are also taking risperidone.

Mode of Action

How Does It Work?

Amiloride+Frusemide / Furosemide contains a combination of amiloride and furosemide as its active substances that work to stop the buildup of extra water in your body. It helps you to pass more urine than you usually do and reduces the extra strain on your heart, blood vessels, lungs, kidneys, or liver.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Amiloride+Frusemide / Furosemide works, or Amiloride+Frusemide / Furosemide itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Amiloride+Frusemide / Furosemide should not be used with medicines that can change the amount of potassium in your blood like potassium supplements, potassium chloride, diuretics (triamterene).
  • Care should be taken if you are using medicines to treat heart failure (digoxin), high blood pressure (ramipril, losartan), pain/fever (indomethacin, aspirin), mental illness (lithium, risperidone), diabetes (sitagliptin, metformin), asthma/chronic obstructive pulmonary disease (theophylline, salbutamol), muscle relaxants (d-tubocurarine), fits/seizures (phenytoin, aminoglutethimide), inflammation (corticosteroids), gastric ulcer (carbenoxolone), laxatives (bisacodyl), depression (reboxetine), fungal infections (amphotericin), cancer (methotrexate), gout (probenecid), bacterial infections (cefalexin).
  • Sucralfate may reduce the effect of Amiloride+Frusemide / Furosemide and must not be taken together.
  • Amiloride+Frusemide / Furosemide may increase the risk of hearing damage when used with aminoglycosides (gentamicin) or platinum-based anticancer medicines (cisplatin).
  • The use of Amiloride+Frusemide / Furosemide with cyclosporine increases the risk of gouty arthritis.

Dosage

Overdose

  • The symptoms of overdose of Amiloride+Frusemide / Furosemide are dry mouth, thirst, muscle cramps, vomiting, dizziness, sleepiness. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of the medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

Frequently Asked Questions (FAQs)

Yes, the combination of amiloride and furosemide is also known as co-amilofruse and is the same as Amiloride+Frusemide / Furosemide.

Amiloride+Frusemide / Furosemide will work to stop the buildup of extra water in your body. It will help you to pass more urine than you usually do and reduce the extra strain on your heart, blood vessels, lungs, kidneys, or liver.

Your doctor will suggest when you should take Amiloride+Frusemide / Furosemide. However, it is important that you take this medicine at the same time everyday.

No, Amiloride+Frusemide / Furosemide is not known to cause erectile dysfunction.

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