Acenocoumarol

• Treatment and prevention of diseases where the blood vessels are obstructed (thromboembolic diseases) such as Deep vein thrombosis (mainly affects legs) and other disorders related to the heart, lungs and brain due to blood clot formation.
• As an adjuvant in the treatment of obstruction of blood flow through the heart due to blood clot (coronary occlusion).

When should one not use Acenocoumarol

• If you are allergic to acenocoumarol or any ingredient of this medicine
• If you are at a risk of bleeding due to blood disorders.
• If you have high blood pressure or accumulation of fluid around the heart.
• If you have a recent history of stroke due to bleeding in the brain or brain haemorrhages.
• If you have stomach ulcers or intestinal bleeding, bleeding in the urinary tract or respiratory tract.
• If you recently had or about to have surgery, have a severe liver or kidney problem, pregnant or planning a baby.
• People who are difficult to co-operate such as alcoholics, with mental deterioration or psychiatric disorders.

Common side effects of this drug are:

Other General Warnings

• You have liver problem as the liver is the main site of the formation of blood clotting factors, and it can be affected.
• You have known medical conditions like kidney or heart problem, the dose will be decided depending upon the severity of your underlying conditions.
• You are suffering from a blood disorder like abnormal bleeding after injury; caution is required for such patients.
• You are an older person or giving it to a child, be cautious and more frequent monitoring of PT/INR is recommended.
• You are suffering from a rare condition where calcium builds up in blood vessels in the skin, as these medicines contain calcium.
• You have disorders due to which absorption from the gut is not proper.
• You have increased thyroid levels, infection or inflammation, cancer or tumour.
• You experience bleeding problems, reach out to your doctor.

How Does It Work?

Interactions with other medicines

• Sometimes medicines can interfere with the action of Acenocoumarol or Acenocoumarol itself can affect the action of other medicines taken at the same time.
• Always inform your doctor about all the medicine you are taking, that includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatment if you are taking for any disorder.
• In particular if you are on certain medications like antiplatelet medicines, anticoagulants like heparin, antibiotics like clindamycin, medicines used to treat heart and brain related disorders, cholesterol lowering medicines painkillers etc.
• Other medicines that should be used with caution are cholesterol lowering medicines like atorvastatin, medicines used to treat underactive thyroid gland like levothyroxine, anti-HIV medicines etc.
• The anticoagulant effect of Acenocoumarol may be diminished, when taken along with certain medicines such as anti-cancer medicines, anti-epileptic medicines, St John's Wort (herbal medicine for brain disorder), oral contraceptives, water pills like furosemide, immunosuppressants etc.

Interactions with food items

Overdose

Missed a Dose