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Molecule Description

Gliclazide+Metformin is a combination medicine. It is used in the treatment of

type 2 diabetes mellitus. It helps in controlling the blood sugar levels adequately. This combination belongs to an anti-diabetic class of medicines. Gliclazide+Metformin is available in the form of tablet, capsule. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.


Uses of Gliclazide+Metformin

Gliclazide+Metformin is used for the treatment of type 2 diabetes mellitus.

Contraindications of Gliclazide+Metformin

When should one not use Gliclazide+Metformin

  • If you are allergic to gliclazide, metformin or similar medicines
  • If you have uncontrolled diabetes along with nausea, vomiting, diarrhoea, weight loss, stomach pain, etc
  • If you have diabetic pre-coma
  • If you have problems with your heart, liver or kidneys
  • If you have any severe infection
  • If you have a hereditary disease - porphyria
  • If you are suffering from dehydration
  • If you are taking a medicine called miconazole to treat fungal infections
  • If you consume alcohol in excess
  • If you are a breastfeeding mother

Side effects of Gliclazide+Metformin

Common side effects of this drug are:

  • Indigestion
  • Constipation
  • Blurred vision
  • Skin problems
  • Increased liver enzymes or jaundice

Precautions and Warnings of Gliclazide+Metformin



Can I take gliclazide+metformin during pregnancy?
It is not advised to use gliclazide+metformin during pregnancy, consult your doctor before using it.

Breast Feeding

Can I take gliclazide+metformin while breastfeeding?
Consult your doctor before using gliclazide+metformin while breastfeeding as it passes into breast milk in low amounts.


Can I drive if I have taken gliclazide+metformin?
No information is available on the ability to drive or use machines, however, if you experience any side effect after taking gliclazide+metformin, then it is advisable not to drive or use machines. Contact your doctor for further information.


Can I consume alcohol with gliclazide+metformin?
No information is available on the interactions of gliclazide+metformin when taken with alcohol. Consult your doctor for further information.

Other General Warnings

Talk to your doctor if
  • You have problems with your liver or kidney
  • You are at risk of having high blood sugar
  • You are suffering from any kind of infection
  • You have a blood enzyme deficiency (glucose-6-phosphate dehydrogenase deficiency)
  • You have a history of an allergic reaction
  • You are suffering from dehydration
  • You have undergone any surgery
  • Gliclazide+Metformin has not been studied in children and adolescents

Mode of Action of Gliclazide+Metformin

How Does It Work?

Gliclazide+Metformin acts by stimulating insulin secretion from the β-cells of the pancreas and increasing the amount of insulin released by the pancreas. It also helps to restore the body's proper re...
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Interactions of Gliclazide+Metformin

Interactions with other medicines

  • Some medicines can affect the way gliclazide+metformin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking water pills, oral contraceptives or are taking medicines used in psychiatric illness, tuberculosis fits or epilepsy.

Content Details


Dr. Mansi Savla

B. Pharm, PharmD


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: In which all dosage forms is gliclazide+metformin available?

A: Gliclazide+Metformin is available in the form of tablet and capsule.

Q: Is gliclazide+metformin an anti-diabetic medicine?

A: Yes, gliclazide+metformin is an anti-diabetic medicine.
Last Updated on: 22 Dec 2021 | 10:51 AM (IST)
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