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Domperidone+Naproxen

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Molecule Summary

Uses
Migraine, pain, inflammation
Therapy
Migraine Drugs
Side Effects
Headache, sleepiness, dizziness, rashes
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Molecule Description

Domperidone+Naproxen is an anti-migraine medicine. It contains a combination of naproxen and domperidone as active substances. Naproxen is an anti-inflammatory medicine, while domperidone is an anti-emetic agent. It is used in the treatment of migraine headaches. It is also used in inflammatory (pain and swelling) conditions of the joints like rheumatoid arthritis and other forms of arthritis. It works by blocking the effect of inflammation-causing substances and producing relief in symptoms. This medicine also controls nausea and vomiting. Avoid taking this medicine if you have a heart rhythm problem or history of ulcers due to pain killers. Long-term treatment with this medicine can affect your liver and kidneys. Take this medicine as suggested by the doctor and in the dose and duration prescribed. Before using this medicine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history. This medicine should not be used in children below 5 years of age.

Uses

  • Domperidone+Naproxen is used to relieve pain, swelling, and discomfort associated with different forms of arthritis and other conditions.
  • It is also used to prevent migraine (intense headaches with nausea, vomiting, and sensitivity to light and sound).

Contraindications

When should one not use Domperidone+Naproxen

  • If you are allergic to naproxen, domperidone, or any other ingredients of Domperidone+Naproxen.
  • If you have an allergy to painkillers like aspirin or ibuprofen. If you are not sure what these medicines are, please confirm with your doctor.
  • If you have a history of ulcers or bleeding.
  • If you have severe heart, liver, or kidney problems.
  • If you're pregnant or think you may be pregnant or breastfeeding.
  • If you have a pituitary gland tumour that releases an excess of prolactin hormone (prolactinoma).
  • If you have an obstruction, blockage, or perforation (tear) in the intestine or any part of the gut.
  • If you have any condition due to which there is a salt imbalance in your body (low levels of potassium or magnesium or high level of potassium).

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Tiredness
  • Sleepiness
  • Rashes

Precautions and Warnings

Pregnancy

Pregnancy

Domperidone+Naproxen should be avoided during pregnancy.

Breast Feeding

Breast Feeding

Domperidone+Naproxen passes into human milk. Thus, either medicine or breastfeeding should be discontinued.

Driving

Driving

Domperidone+Naproxen may cause dizziness, drowsiness, fatigue, and vision problems. Therefore, you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Alcohol

You should not consume alcohol while on treatment with Domperidone+Naproxen, as the chances of stomach ulceration and bleeding increase.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have any stomach and intestinal diseases.
  • You smoke or consume alcohol regularly.
  • You are above 65 years of age.
  • You had or have problems with your heart, liver, or kidney.
  • You have diabetes or high blood pressure or high cholesterol.
  • You have asthma or any problems with your breathing.
  • You are planning to have a baby, as Naproxen may interfere with female fertility.
  • You are using other medicines that may cause bleeding and ulcers in the stomach.
  • You have to undergo any blood or urine tests.
  • You are taking medicines or painkillers for headaches too often.
  • You are above 12 years of age with a body weight below 35 kgs.
  • You are taking apomorphine.
  • You have developed an allergy or skin rash after taking this medicine.
  • You have an autoimmune disorder called systemic lupus erythematosus or any tissue disorder or any blood clotting issues.
  • You have Parkinson's disease, asthma, colitis, or Crohn's disease.

Mode of Action

How Does It Work?

  • Domperidone+Naproxen contains a combination of naproxen and domperidone as active substances.
  • Naproxen belongs to a group of medicine that blocks the effect of inflammatory chemicals. So, the symptoms like redness, pain, inflammation, and swelling improve gradually.
  • Domperidone is used to control nausea and vomiting. It prevents food from coming back up in the oesophagus (food pipe), which may occur due to stomach irritation caused by naproxen and other painkillers and in migraine attacks.

Interactions

Interactions with other medicines

  • Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
  • Particular care should be taken if you are taking blood thinners (such as warfarin), aspirin or other painkillers of the NSAID group, steroids, blood pressure medicines, water pills (diuretics), lithium, methotrexate, certain antibiotics (such as erythromycin or clarithromycin), certain antifungals (such as ketoconazole) or other medicines that can affect the heart rhythm.

Interactions with food items

Take Domperidone+Naproxen after meals to avoid stomach discomfort.

Dosage

Overdose

Symptoms of overdose of Domperidone+Naproxen are nausea, vomiting, stomach pain, diarrhoea, dizziness, sleepiness, excitement, and irritation. If you experience any of the symptoms or think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Missing a dose of Domperidone+Naproxen may reduce the effectiveness of the treatment. If you forget a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

Frequently Asked Questions (FAQs)

You should preferably take Domperidone+Naproxen after meals, to avoid stomach discomforts.

Domperidone+Naproxen is used to relieve pain, swelling and discomfort associated with different forms of arthritis and other conditions. It is also used to prevent migraine (intense headaches with nausea, vomiting and sensitivity to light and sound).

Yes, Domperidone+Naproxen is a painkiller medicine that is used to relieve pain, swelling and discomfort in arthritis and other conditions like migraine.

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