Monocef 1g Injection
1 Powder For Injection(s) in Dry VialProduct Summary
Monocef 1 g Injection is used to treat bacterial infections and prevent infection during surgery, and is made by Aristo Pharmaceuticals. It contains ceftriaxone 1 g, an antibiotic that stops bacteria forming their cell wall, causing the bacteria to die.
Medically Reviewed by Dr. Nikita Toshi
Last updated on: 13 October 2026 | 9:13 AM (IST)
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Dose Form
POWDER FOR INJECTION
Expiry
General Information
| Therapy | Antibiotic |
| Composition | Ceftriaxone(1.0 G) Ceftriaxone 1.0 G |
Ceftriaxone 1.0 G

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*Offer applicable on orders above ₹1000About Monocef 1
Monocef Injection is an antibiotic containing ceftriaxone, a medicine from the cephalosporin group. It is used to treat severe bacterial infections such as those affecting the brain, lungs, ear, stomach, urinary tract, joints, skin, and also to prevent infections during surgery. It works by stopping bacteria from forming their protective cell wall, which ultimately kills them.
This medicine is only administered in a hospital or clinic under the supervision of a doctor or nurse. You should never inject it yourself. Your healthcare provider will determine the correct dose based on the type and severity of the infection.
Monocef Injection can be given either as a slow drip into your vein (intravenous infusion) or as an injection directly into a vein or muscle. The method depends on your condition and the doctor’s advice.
Some people may experience mild side effects after receiving this injection, such as diarrhoea, headache, dizziness, changes in blood test results, or pain at the injection site. These usually resolve on their own without any treatment.
If any side effect becomes severe or persists, inform your doctor immediately. Always complete the prescribed course of treatment to ensure the infection is fully cured and to prevent bacteria from becoming resistant to the medication.
Uses
Contraindications
- If you are allergic to Ceftriaxone or any other ingredients of Monocef injection.
- If you are allergic to a class of medicines known as cephalosporin.
- If you are allergic to medicines like penicillins, monobactams and carbapenems.
- If a newborn is suffering from jaundice or is on calcium injection treatment.
- If a newborn is suffering from increased bilirubin in the blood.
- Ceftriaxone solution containing lidocaine should not be given as an injection.
Side effects
- Increased number of eosinophils
- Diarrhoea, loose stools
- Increased liver enzymes
- Rash
- Fungal infections
- A decrease in white blood cells
- Decreased red blood cells (anaemia)
- A bleeding disorder like coagulopathy (a condition in which the ability of blood to form clots is decreased)
- Headache
- Dizziness
- Nausea
- Vomiting
- Itching at the injection site
- Pain at the injection site
- Fever
- Increased creatinine levels in the blood
Doctor’s suggestion

Precautions and Warnings
Alcohol
SAFEAlcohol may worsen the side effect like dizziness along with Monocef injection . It is advisable to avoid alcohol.
Pregnancy
WITH CAUTIONSince there is limited safety data available on the use of Monocef injection in pregnant women, Monocef injection must only be used during pregnancy (in particular in the first trimester of pregnancy) if considered essential by your doctor after assessing the benefits over risks.
Breastfeeding
SAFEComponents of Monocef injection pass into breast milk. Inform your doctor if you are breastfeeding, your doctor will tell you about the use of this medicine after assessing the need and benefit.If prescribed, monitor your child closely for antibiotic-related side effects like diarrhoea or fungal infection of the mouth.
Driving
WITH CAUTIONYou may feel dizzy after taking Monocef injection, thus be cautious or avoid driving after taking this injection.
Other General Warnings
- You have liver diseases.
- You have kidney diseases or kidney stones.
- You are suffering from gallstones.
- You are suffering from anaemia (which reduces red blood cells).
- You are suffering from bowel inflammation.
- You have a stomach disease or problems like diarrhoea after taking antibiotics.
- You have recently taken any medicine containing calcium.
- Planning to get a blood test? It may interfere with the results.
- Monocef injection should not be given to premature babies.
Directions for use
- Monocef injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
Doctor’s suggestion

Dosage
Missed a dose
- You will be monitored by your doctor or nurse on when Monocef injection should be given to you.
- It is unlikely that the dose will be missed.
- However, if you think your doctor or nurse might have missed a dose, inform them.
- It is advisable not to miss any dose of antibiotics as it can fail therapy.
Overdose
- Your doctor or nurse will give Monocef injection, therefore chances of an overdose are rare.
- However, if you experience nausea, vomiting, diarrhoea and stomach upset immediately after taking this injection, inform your doctor or reach out to your nearest hospital as soon as possible.
How Monocef 1 works
Interactions
Drug interactions of Monocef 1 with other medicine salt
Food interactions
Follow your doctor or pharmacist advice about taking this medicine with food.
Frequently asked questions
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References
- Ceftriaxone 1 g powder for solution for injection or infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 March 2025]
- Ceftriaxone 1 g powder for solution for injection or infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 21 March 2025]
- CEFBACT T Injection (Ceftriaxone + Tazobactam) [Internet]. Ciplamed.com. 2021 [cited 21 March 2025]
- Torocef XP Injection [Internet]. Torrentian.com. 2026 [cited 18 May 2026]
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