Duolin 3 Respules 5x3ml
5 Respule(s) in Packet
Product Summary
Duolin 3 500 mcg/1.25 mg 3 ml Respule, from Cipla, combines ipratropium 500 mcg and levosalbutamol 1.25 mg to treat COPD-related bronchospasm, wheezing, chest tightness and breathing difficulty. Ipratropium blocks airway-tightening signals. Levosalbutamol, a short-acting bronchodilator, relaxes airway muscles to improve airflow.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 7:41 PM (IST)
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RESPULE
Expiry
General Information
| Therapy | Drugs for chronic obstructive pulmonary disease, anti-asthmatic |
| Composition | Ipratropium(500.0 Mcg)+Levosalbutamol / Levalbuterol(1.25 Mg) Ipratropium 500.0 Mcg+Levosalbutamol / Levalbuterol 1.25 Mg |
Ipratropium 500.0 Mcg+Levosalbutamol / Levalbuterol 1.25 Mg
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*Offer applicable on orders above ₹1000About Duolin
Duolin 3 Respules is used to treat the symptoms of chronic obstructive pulmonary disease (COPD), like difficulty in breathing, coughing, and wheezing. It contains a combination of ipratropium and levosalbutamol as active ingredients. It works by decreasing the narrowing of the smooth muscles of the airways. Duolin respules also relax the muscles of the airways and make breathing easier.
COPD is a lung disease in which the lungs become swollen and the flow of air in and out decreases. This obstruction results in coughing, wheezing, and breathing difficulties. Take this medicine exactly as prescribed by your doctor.
Duolin 3 respules should always be administered with the help of nebulizers. A nebulizer is a machine that forms a mist of medicine so that it can reach the lungs easily. Your doctor or pharmacist will guide you on how to use nebulizers properly.
Iprazest respules, Combimist respules, Salbair I transpules and Nebzmart smartpules are other medicines containg simillar compositions.
Do not take Duolin 3 respules if you are allergic to any of its components. Before starting this medicine, inform your doctor if you are pregnant, planning on becoming pregnant, or breastfeeding, and about your complete medical history. Also, inform the doctor about all other medicines and supplements you take.
Uses
Doctor’s suggestion
Contraindications
- If you are allergic to ipratropium or levosalbutamol or any other ingredients of Duolin 3 respules.
- If you are allergic to atropine or its derivatives.
- If you have any problems with your heart.
- If you are below 12 years of age.
Side effects
- Nausea
- Vomiting
- Dry mouth
- Constipation
- Headache
- Dizziness
Doctor’s suggestion
Precautions and Warnings
Alcohol
WITH CAUTIONAlcohol intake along with the use of Duolin respules can make you more dizzy or drowsy. Thus, you should avoid consuming alcohol while taking this medicine.
Pregnancy
WITH CAUTIONThere is limited information about the effects of Duolin respules in human pregnancy.
Breastfeeding
SAFEIt is unknown if the components of the Duolin respules passes into human milk. Hence, you should consult your doctor before using this medicine while breastfeeding.
Driving
WITH CAUTIONThere is limited information about the effects of Duolin respules on driving but this medicine may cause dizziness and blurring of vision, you should avoid driving if you do not feel well or are unable to be alert.
Other General Warnings
- You are suffering from heart, liver or kidney problems.
- You have diabetes, glaucoma or fits.
- You have high blood pressure or an overactive thyroid gland.
- You have difficulty passing urine due to bladder problems or an enlarged prostate (mostly in men).
- You are suffering from a condition called cystic fibrosis. It increases the chances of stomach disturbances You use Duolin with it.
Directions for use
- Duolin 3 respules should only be given using a nebuliser with a face mask linked to an air compressor and under the supervision of a doctor.
- Remove the pouch, open one respule, squeeze the contents into the nebulizer, and discard the respule. Your doctor will determine the appropriate dose and duration based on age, weight, and medical condition.
- Do not dilute the content, inhale it directly, or swallow it. Dispose any leftover solution and opened respules.
Storage and disposal
- Store Duolin respules below 25°C in a clean and dry place, protected from moisture, sunlight and heat.
- Keep the medicine away from children and pets.
Quick tips
- Clean the nebulizer after every use as per the instructions mentioned.
- It is recommended to rinse your mouth with water after inhalation of this medicine.
- You may develop oral fungal infection and an increase in wheezing after using this medicine.
- Do not stop taking Duolin respules without consulting your doctor, even if you feel relieved after taking a few doses.
- Antifungal medicines such as Ketoconazole and Itraconazole should not be taken along with Duolin respules.
- The chances of side effects increase significantly in the elderly population, so elderly patients should be cautious while using this medicine.
- This medicine is not recommended for use in children below 12 years of age.
- Duolin should be used with caution in elderly patients, people with atrial fibrillation, diabetes, or cancer, and only under medical supervision based on individual risk factors.
- Duolin with Seroflo (including in very young children such as 5 months or 3 years) should only be used if specifically prescribed by a doctor, as combination inhaled therapies require monitoring.
Dosage
Overdose
- The symptoms of overdose are headache, dry mouth, palpitation, nausea, dizziness, fatigue, fever, sleeplessness, nervousness, shakiness, restlessness, confusion, hallucinations, fits, chest pain, high or low blood pressure or irregular heartbeats.
- If you experience any of the symptoms or think you have taken too much Duolin respules, contact your doctor immediately or visit the nearest hospital.
Missed a dose
How Duolin works
Doctor’s suggestion
Interactions
Drug interactions of Duolin with other medicine salt
Food interactions
Frequently asked questions
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References
- DrugBank. Ipratropium [Internet]. 2025 [cited 11th Nov 2025]
- DrugBank. Levosalbutamol. [Internet]. 2025 [cited 11th Nov 2025]
- Koc Z, Bilgic S, Koc Y, et al. Levosalbutamol. Clin Cardiol. 2007 Apr;30(4):187-92. doi: 10.1002/clc 20143. PMID: 17337829. 2025 [cited 11th Nov 2025]
- ScienceDirect. Levosalbutamol. ScienceDirect. 2025 [cited 11th Nov 2025]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 11 November 2025]
- MedlinePlus. Ipratropium [Internet]. U.S. National Library of Medicine; 2026 [cited 26th May 2026]
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