Corex DX Syrup
100ml Syrup in BottleProduct Summary
Corex DX Syrup, from Cipla, combines dextromethorphan 10 mg and chlorpheniramine 4 mg for short-term relief of dry cough, sneezing and runny nose associated with the common cold or respiratory allergies. Dextromethorphan suppresses the brain's cough reflex. Chlorpheniramine blocks histamine, the chemical involved in allergy symptoms.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 2:49 PM (IST)
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SYRUP
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General Information
| Therapy | Cough cold preparation |
| Composition | Dextromethorphan(10.0 Mg)+Chlorpheniramine / Chlorphenamine(4.0 Mg) Dextromethorphan 10.0 Mg+Chlorpheniramine / Chlorphenamine 4.0 Mg |
Dextromethorphan 10.0 Mg+Chlorpheniramine / Chlorphenamine 4.0 Mg

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*Offer applicable on orders above ₹1000About Corex
Corex Dx syrup is a combination medication used to relieve cold symptoms, including cough, sneezing, and a runny nose. It contains chlorpheniramine, an antihistamine, and dextromethorphan, a cough suppressant. Chlorpheniramine works by blocking the receptors to which histamine binds, thereby preventing or reducing the allergic response. Cough is produced when the cough center in the brain is activated.
Dextromethorphan acts as a cough suppressant by directly affecting these specific areas in the brain, essentially deactivating the cough reflex and providing relief from coughing. Chlorpheniramine tackles allergic symptoms at the source by blocking histamine, while dextromethorphan works on the central nervous system to suppress the cough reflex.
This syrup should be taken exactly as prescribed by your doctor. Common side effects include nausea, upset stomach, and rash. These side effects are usually temporary, but contact your doctor if they persist or worsen. Corex Dx syrup may cause dizziness and drowsiness, so avoid driving or engaging in activities that require mental focus. Avoid alcohol consumption while taking this medication. Corex Dx cough syrup should not be used in children below 2 years of age.
Norvent D syrup, Dilo Dx syrup, Hhlinctus syrup, and Glycodin syrup also contain chlorpheniramine and dextromethorphan.
According to the advisory issued by the Union Health Ministry, cough and cold medications should not be prescribed or dispensed to children under two years of age. These medications are generally not recommended for children under five years old. For children above that age, any use should be based on careful clinical evaluation and close supervision
Uses
Contraindications
- In case you are allergic to chlorpheniramine, dextromethorphan or any other components of this syrup.
- If you are having or had medicines like sodium oxybate (used to prevent day time sleepiness)
- If you are taking or have taken monoamine oxidase inhibitors such as phenelzine, selegiline (used to treat mental illness or Parkinson's disease) at least two weeks before starting treatment woth this syrup . In case you don't know whether your prescription includes such medicines, ask your doctor before taking Corex Dx syrup.
Side effects
- Drowsiness
- Sleepiness
- Dizziness
- Tiredness
- Upset stomach
- Headache
- Nausea
- Vomiting
Precautions and Warnings
Alcohol
UNSAFECorex Dx syrup may produce drowsiness or sleepiness as a side effect, so if you consume it along with alcohol, it may exaggerate the drowsiness or sleepiness. Thus, you should avoid consuming alcohol while on treatment with this cough syrup.
Pregnancy
WITH CAUTIONThere is limited information available on the safety of Corex Dx syrup in human pregnancy. You should consult your doctor before using this cough syrup during pregnancy or if you think you may be pregnant. This syrup should be used only if it is needed and advantage overweighs the risk.
Breastfeeding
WITH CAUTIONThere is no safety information about the effects of Corex Dx syrup during breastfeeding. Thus, it is unknown if the components of Corex Dx syrup pass into human milk. You should consult your doctor before using cough syrup during breastfeeding.
Driving
WITH CAUTIONCorex Dx syrup produces blurring of vision and drowsiness as side effects. You should avoid driving if you do not feel well or are unable to stay alert.
Other General Warnings
- You have a cough for a long time with a lot of mucus (like asthma, emphysema or smoking).
- You have eye problems like glaucoma (increased pressure in the eye).
- You have difficulty in urination and a frequent urge to urinate (enlarged prostate).
- You have problems with your heart and liver.
- You have any breathing problems, high blood pressure and fits.
- In young children, this medicine may produce excitement instead of drowsiness. Be cautious while giving this syrup to children.
- Older people should be cautious while using Corex Dx syrup, as they are more prone to develop dizziness and urination difficulties with this syrup.
- It is not recommended to use this syrup in children below 2 years of age.
Directions for use
- Take Corex Dx syrup as directed by the doctor.
- Shake well before the use and use a measuring cup or spoon for measurement.
- Do not take more than four doses in 24 hours.
Storage and disposal
- Store Corex Dx syrup below 25°C in a clean and dry place.
- Please protect it from moisture, sunlight and heat.
- Keep the medicine away from children and pets.
Quick tips
- Corex Dx syrup is used for temporary relief of cough due to throat irritation, sneezing & running nose.
- It should be taken as directed by the doctor and in doses and duration as prescribed.
- Shake well before use. Use a spoon or measuring cup for the exact quantity.
- Before starting Corex Dx syrup, inform your doctor if you are pregnant, planning on becoming pregnant, or breastfeeding. Also, inform about all other medicines that you take and your complete medical history.
- Drowsiness, nausea, vomiting, dizziness, and headache can be seen as side effects of this medicine, inform your doctor if the side effects do not resolve over time.
- Corex Dx syrup may cause sleepiness, dizziness, vision disturbances, or loss of coordination. If you experience any such effects after taking this medicine, avoid driving, operating heavy machinery, or performing any such tasks which require mental alertness.
- Do not take this medicine if you are allergic to chlorpheniramine, dextromethorphan or any other components of this syrup.
Dosage
Overdose
Missed a dose
How Corex works
- Natural substances like Histamine released in our body are responsible for allergies such as sneezing or runny nose
- Chlorpheniramine blocks the effect of these substances and provides relief in symptoms of a common cold
- There are specific areas in the brain (cough centre) which when activated produces coughing
- Dextromethorphan affects these areas and deactivates them, thus helps in relieving the coughing
Interactions
Interactions with other medicines
- Corex Dx syrup should not be taken with a medicine called monoamine oxidase inhibitors (MAOIs) because it produces a condition called serotonin syndrome which is a life-threatening condition that can occur rapidly due to a build-up of an excessive amount of serotonin in the body.
- In the case of serotonin syndrome, a person may experience high body temperature, high blood pressure, fast heart rate, excitability, tremor (shakiness), and sweating. In such a situation patients should rush to a nearby hospital.
- Corex Dx syrup should be used cautiously with other medicines like Codeine, Hydrocodone (used for cough) that cause drowsiness. Alcohol, Marijuana, medicines to treat mental illness (Alprazolam, Lorazepam, Zolpidem, etc.), muscle-relaxing medicines ( Carisoprodol, Cyclobenzaprine), other antihistaminic medicines (Cetirizine, Diphenhydramine, etc.) should be consumed with caution.
Food interactions
Frequently asked questions
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References
- Pfizer. Corex D Syrup [Internet]. Pfizerpro.com 2025 [cited 25th September 2025]
- DailyMed - Children's Accudial [Internet]. Dailymed.nlm.nih.gov. 2021 2025 [cited 25th September 2025]
- COREX Dx Cough Syrup (Chlorpheniramine Maleate and Dextromethorphan Hydrobromide) [Internet]. Labeling.pfizer.com. 2021 2025 [cited 25th September 2025]
- Chlorpheniramine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2021 2025 [cited 25th September 2025]
- Dextromethorphan: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2021 2025 [cited 25th September 2025]
- Oh SR, Agrawal S, Sabir S, et al. Dextromethorphan. [Updated 2023 May 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. 2025 [cited 25th September 2025]
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 2725, Chlorpheniramine. 2025 [cited 25th September 2025]
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