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Zonil Tablet

10 Tablet(s) in Strip
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Zonil Tablet Description

Zonil Tablet is a prescription medicine used to treat Schizophrenia and Schizophrenia‐like illnesses. Schizophrenia is a mental disorder characterised by episodes of hallucinations, delusions, and ex

remely disordered thinking and behaviour. Zonil Tablet can also be used to treat non-psychotic anxiety disorder. Zonil Tablet is a combination medicine that contains Trifluoperazine and Trihexyphenidyl (Benzhexol Hydrochloride) as the active ingredients. This medicine works by affecting specific chemical messengers, which improve mood, thoughts, and behaviour. Zonil Tablet dosage should be as doctor's prescription. Stopping this medicine suddenly without consulting your doctor can cause worsening of your condition or may lead to withdrawal-like symptoms.

Product Summary

Offer Price₹23.38
You Save₹4.12 (15% on MRP)
ContainsTrifluoperazine(10.0 Mg) + Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg)
UsesSchizophrenia, Non-psychotic anxiety disorder.
Side effectsNausea, Constipation, Sleepiness, Dizziness, Abdominal pain, Dry mouth, Weight gain.
Check more medicines with composition as Trifluoperazine(10.0 Mg) + Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg)

Uses of Zonil Tablet

  • As per CDSCO and USFDA, Zonil Tablet is used for-
  • Treatment of Schizophrenia.
  • Treatment of non-psychotic anxiety disorder.

Contraindications of Zonil Tablet

  • If you are allergic to the ingerdients of Zonil Tablet.
  • If you have low blood pressure (hypotension).
  • If you have diabetes or epilepsy.
  • If you have Parkinson's disease or dementia.
  • If you have a seizure disorder.
  • If you have heart disease.
  • If you have prostate or bladder problems.
  • If you have kidney or liver problems.
  • If you are pregnant or breastfeeding.
  • If you have respiratory issues.
  • If you are at high risk of having a stroke.

Side effects of Zonil Tablet

  • Nausea
  • Constipation
  • Sleepiness
  • Dizziness
  • Abdominal pain
  • Dry mouth
  • Weight gain

Precautions and Warnings of Zonil Tablet


Can I take Zonil Tablet during pregnancy?
If you are pregnant, consult with your doctor before taking Zonil Tablet. as it can be unsafe to use during pregnancy. There is limited information available regarding the safety of Zonil Tablet in pregnant women, but animal research has shown some harmful effects in developing unborn babies.

Breast Feeding

Can I take Zonil Tablet while breastfeeding?
Zonil Tablets can be unsafe during breastfeeding. It may get excreted into breast milk and can affect the baby. Consult your doctor and discuss the potential risks and benefits of taking Zonil Tablet.


Can I drive if I have taken Zonil Tablet?
Do not drive after taking the Zonil Tablet. It may cause side effects that could hamper your ability to drive. You may experience blurring of vision, dizziness, mental confusion, nausea (mild), drowsiness, and other side effects in some cases.


Can I consume alcohol with the Zonil Tablet?
No, do not consume alcohol with Zonil Tablet, as it increases the severity of side effects like dizziness, drowsiness, lethargy, blurred vision, liver injury, etc. It may also worsen the symptoms for which you are taking this medicine.

Other General Warnings

Talk to your doctor if
  • You have any allergic reactions after taking the Zonil Tablet.
  • You notice suicidal ideation or self-harming thoughts.
  • You experience any severe side effects persistently.
  • You have abnormal muscle movements.
  • You have any previous mild liver or kidney conditions. This medicine may need a dose adjustment.
  • You have withdrawal symptoms like agitation, nausea, tremor, sweating, and confusion.
  • You are using any ayurvedic medicines, vitamins, and other health supplements. Talk to your doctor about what prescription and non-prescription medications, herbal products, and nutritional supplement...
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Mode of Action of Zonil Tablet

How Does It Work?

Zonil Tablet is a combination medicine that contains Trifluoperazine-10 mg and Trihexyphenidyl (Benzhexol Hydrochloride)-2 mg as the active ingredients. Trifluoperazine belongs to the antipsychotic ...
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Directions for Use of Zonil Tablet

  • Take the Zonil Tablet as prescribed by the doctor.
  • You can take Zonil Tablet with food or without, or as prescribed.
  • Take Zonil Tablet on a regular schedule, preferably at the same time every day.
  • Swallow the whole tablet orally with a glass of water. Do not break/crush the tablet.
  • Do not take Zonil Tablet with other medications without consulting your doctor.
  • Don’t stop taking Zonil Tablet suddenly, as it may lead to withdrawal side effects.
  • Don’t exceed the dosage of Zonil Tablet, even if you cannot feel its effects.

Interactions of Zonil Tablet

Interactions with other medicines

  • Zonil Tablet interacts with anxiety medicines, such as diazepam, clonazepam, chlordiazepoxide, alprazolam, and lorazepam may lead to sedation and drowsiness.
  • Zonil Tablet interacts with blood-pressure-lowering medicine, such as amlodipine, lisinopril, losartan, or metoprolol can lead to extremely low blood pressure.
  • Zonil Tablet interacts with pain killers, such as morphine, oxycodone, fentanyl, hydrocodone, tramadol, and codeine may cause more sedation and drowsiness.
  • Zonil Tablet interacts with anti-Parkinson’s medicines such as levodopa may reduce the effects of levodopa.
  • Zonil Tablet interacts with antifungal medications like itraconazole and ketoconazole can reduce its effects.
  • Zonil Tablet interacts with antidepressants or mood-elevating medicines like fluoxetine and desipramine, leading to increased blood levels of Trifluoperazine and causing increased side effects.

Storage and disposal of Zonil Tablet

Store Zonil Tablet away from sunlight in a cool and dry spot. Ensure the medication is out of reach from children and pet animals. Keep your tablets in the pack until it is time to take them. Do not f...
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Dosage of Zonil Tablet


Zonil Tablet overdose can result in symptoms like abdominal pain, dizziness, fainting, vomiting, breathing difficulties, sedation, fast pounding or irregular heartbeat, hypotension, and seizures. If y...
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Missed a Dose

If you miss a dose of the Zonil Tablet, take it at the earliest. In case it's already time to take the next scheduled dose, skip the missed dose and take the next dose. Consult your doctor if you have...
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Content Details


Dr. Zishan Ahmad

Final year MBBS Student


Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)


Q: What other precautions should I take while taking Zonil Tablet?

A: Zonil Tablet may cause dizziness and fainting while getting up from bed from a lying position. Hence, stand up slowly from the lying position. The Trifluoperazine component of Zonil Tablet may make your skin sensitive to sunlight. You must avoid unnecessary or prolonged exposure to direct sunlight or wear sunglasses or apply sunscreen to protect yourself from sunlight.

Q: How much time does Zonil Tablet take to show its desired effect?

A: It takes around 4-6 weeks for Zonil Tablet to show its effect clinically. However, the results vary from person to person and disease condition. Stay in touch with your doctor during the first few weeks of starting this treatment and complete the full course of treatment.

Q: Can I discontinue Zonil Tablet on my own after I feel improvement in my symptoms?

A: No, suddenly stopping the consumption of Zonil Tablet causes withdrawal symptoms like confusion, depression, nervousness or irritability, diarrhoea, vomiting, and sweating. Consult your doctor before stopping the consumption of the Zonil Tablet, as doses need to be tapered slowly to avoid undesirable side effects.
Product Details
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Last Updated on: 13 Apr 2022 | 12:12 PM (IST)

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