Ursobiac Tablet
Description
Ursobiac 300 tablet contains ursodeoxycholic acid, a naturally occurring bile acid produced in the liver. This medication is primarily prescribed for treating liver-related disorders, including primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and cholesterol-based gallstones. It is occasionally used to manage liver conditions associated with cystic fibrosis.
The mechanism of action of the Ursobiac 300 tablet involves reducing cholesterol content in the bile. It should be swallowed whole after a meal, accompanied by a glass of milk or water. The dosage will depend on the condition being treated and your body weight. Take it regularly for maximum benefit, for the duration prescribed (several months or longer), even if symptoms disappear.
Common side effects may include abdominal pain, diarrhoea, hair loss, itching, nausea, and rash. Not everyone experiences these side effects. If you have concerns or if the side effects persist, inform your doctor. Before taking this medicine, inform your doctor if you have inflammation of the gallbladder or bile ducts, experience frequent cramp-like pain in your upper abdomen, have been coughing up blood, or have gained weight rapidly.
Ursobiac 300 tablets may interact with other medications, so inform your doctor about all other medications you are currently taking. Women should discontinue hormonal birth control pills, as they can increase the production of gallstones. Ultrasound scans and frequent blood tests may be necessary to monitor your liver function during treatment.
Product Summary
Offer Price | ₹173.64 |
You Save | ₹101.98 (37% on MRP) |
Contains | Ursodeoxycholic Acid / Ursodiol(300.0 Mg) |
Uses | Gallbladder stones and Liver dysfunction |
Side effects | Nausea, vomiting, diarrhoea, sticky stool |
Therapy | DRUGS FOR CHOLELITHIASIS |
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Uses
- Ursobiac 300 tablets are used to dissolve gallbladder stones composed of cholesterol in various liver-related disorders, such as cirrhosis and sclerosing cholangitis (inflammation and scarring of the bile ducts)....
- Liver dysfunction is associated with cystic fibrosis (a hereditary disease that affects the lungs and digestive system).
Contraindications
- If you are allergic to ursodeoxycholic acid or any ingredient of Ursobiac 300 tablets.
- If you have a stomach or intestinal ulcer or bleeding.
- If you have recently had surgery involving any part of your intestine.
- If you have a liver-related disorder and a non-functional gall bladder.
- If you are suffering from a liver or intestinal condition which affects the circulation of bile substances, such as a blockage of the bile duct.
- If you are suffering from inflammation/blockage of the gall bladder or biliary tract.
Side effects
- Nausea
- Vomiting
- Diarrhoea
- Sticky stool
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a history of liver disease or obstruction in bile passage, your doctor may ask you to do a liver function test regularly.
- You experience a persistent diarrhoea, your doctor may discontinue the therapy immediately.
- Women of childbearing age should use non-hormonal contraceptive measures (physical barrier) or low oestrogen oral contraceptive pills. Combination oral contraceptive pills should not be taken with Ursobiac....
- Your doctor may ask you for an ultrasound after six months of the treatment to check the therapeutic improvement.
- It would be best if you avoided a high cholesterol diet during the treatment as it may affect the effectiveness of Ursobiac.
Directions for Use
- Ursobiac 300 tablets should be taken as directed by your doctor. Swallow it whole with a glass of water. Do not cut, break or chew the medicine.
- It should be taken after having your meal. It is best to take it at a fixed time for optimal results.
- You should not consume it more than that prescribed by your doctor.
Storage and disposal
- Store Ursobiac 300 tablets in a cool, dry place, protected from direct sunlight, moisture, and heat.
- Keep it away from children and pets.
- Discard any unused and expired medicine properly. Do not flush it in the toilet or throw it into the drain.
Quick Tips
- Ursobiac 300 tablets are used to dissolve cholesterol-based gallstones and treat liver-related disorders.
- Take the tablet whole with a glass of milk or water after a meal, at the same time each day.
- The dosage is determined by your doctor based on your condition and body weight.
- Avoid a high-cholesterol diet during treatment.
- Inform your doctor about all other medications you are taking, especially hormonal birth control pills, cholesterol-lowering medicines, and antacids.
- Do not take this medicine if you are allergic to ursodeoxycholic acid or have a stomach ulcer, intestinal bleeding, or a non-functional gallbladder.
- Consult your doctor before taking Ursobiac 300 tablets if you are pregnant or breastfeeding.
- If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed one. Do not take a double dose.
- Common side effects can include abdominal pain, diarrhoea, nausea, and rash.
- Regular liver function tests and ultrasound scans may be required during treatment.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Ursobiac 300 tablets may interact with other medications and provide an altered response to the treatment. Notify your doctor if you are undergoing any other treatments, over-the-counter medications (that you buy without a prescription) and herbal preparations. Inform your doctor if you have a planned surgery or vaccination scheduled....
- Hormonal pills should not be used if you are on treatment with Ursobiac 300 tablets.
- Concomitant use of cholesterol-lowering medications, such as cholestyramine or colestipol, and certain antacids may reduce the efficacy of Ursobiac 300 tablets. So, it should be taken at least 2 hours apart....
- Other medicines that may affect the absorption of this tablet include charcoal, antibiotics such as Ciprofloxacin, immunosuppressants like Ciclosporin, cholesterol-lowering medications like Atorvastatin, and Dapsone used as an anti-infective. Hence, it should not be used concomitantly....
Interactions with food items
Content Details

Dr. Mansi Savla
B. Pharm, PharmD

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can Ursobiac reduce raised liver enzymes?
Q: Does high blood cholesterol level cause gallbladder stones?
Q: What is Ursobiac Tablet used for?
- Ursobiac Tablet is used to dissolve gallbladder stones that are made of cholesterol in various liver-related disorders such as cirrhosis and sclerosing cholangitis.
- It is also used in liver dysfunction associated with cystic fibrosis (a hereditary disease that affects the lungs and digestive system).
Q: I'm a woman of childbearing age. What kind of birth control should I be using while on Ursobiac 300 tablet?
Q: What are the side effects of Ursobiac 300 tablet?
References
- DESTOLIT 150 mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 19th September 2025]
- CDSCO - Ursodeoxycholic acid [Internet]. Cdscoonline.gov.in. 2025 [cited 19th September 2025]
- URSO (ursodiol) tablets, for oral use, USP, [Internet]. Accessdata.fda.gov. 2025 [cited 19th September 2025]
- Lactmed - Ursodiol [Internet]. Ncbi.nlm.nih.gov. 2025 [cited 19th September 2025]
- DESTOLIT 150 mg tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 19th September 2025]
- Information H, Diseases D, Eating &, Eating &, Health N. Eating, Diet, & Nutrition for Gallstones | NIDDK [Internet]. National Institute of Diabetes and Digestive and Kidney Diseases. 2025 [cited 19th September 2025]
- Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis Ovadia, Caroline et al. The Lancet Gastroenterology & Hepatology, Volume 6, Issue 7, 547 - 558
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