Tolperitas Dsr Strip Of 5 Tablets
Description
Tolperitas Dsr Tablet is a skeletal muscle relaxant which acts centrally on the spinal cord and also has painkiller properties. It contains Tolperisone and Diclofenac as the active ingredient. Tolper
itas Dsr Tablet used to relieve acute (sudden) muscle spasms and related pain. It works by improving the blood flow towards skeletal muscles and reduces pain. It should not be used for children below 18 years of age and nursing mothers. Side effects like nausea, vomiting, indigestion, bloating are associated with Tolperitas Dsr Tablet. In case you experience any severe side effects or any discomfort while using this medication, it is important to consult the doctor immediately or visit the nearest hospital.
Product Summary
Offer Price | ₹154.00 |
You Save | ₹46.00 (23% on MRP) |
Contains | Tolperisone(450.0 Mg)+Diclofenac(100.0 Mg) |
Therapy | ANALGESIC |
Uses
Contraindications
- If you are allergic to Tolperisone, Diclofenac or any other ingredient of Tolperitas Dsr Tablet.
- If you are suffering from myasthenia gravis, an autoimmune disease characterized by muscle weakness.
- If you are a breastfeeding mother.
- If you have active stomach or intestinal bleeding, ulcer, perforations or peptic ulcers.
- If you have a history of stomach or intestinal bleeding or perforations.
- If you have any heart conditions such as heart failure.
- If you have kidney or liver diseases.
Side effects
- Nausea, vomiting, diarrhoea, indigestion, abdominal pain, flatulence
- Dizziness, headache
- Dryness of the mouth
- Itching, rash
- Muscle pain, muscle weakness
- Increased liver enzymes
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a stomach or intestinal ulcer.
- You experience an allergic reaction after taking Tolperitas Dsr Tablet.
- You are on or taking any other medicines.
- You have severe kidney or liver disease.
- You have any heart disease or condition.
- You have any blood disorder or pre-existing asthma.
- Tolperitas Dsr Tablet should not be used for children below 18 years of age.
Mode of Action
How Does It Work?
- Tolperisone acts on the spinal cord and by blocking the exchange of sodium and calcium ions within the cells, thereby relaxing the muscle.
- Decreased blood supply to various small blood vessels due to muscle contraction can cause trauma to the blood vessels leading to the release of a chemical substance responsible to cause pain. However, Tolperisone works by increasing the blood supply to skeletal muscles....
- Diclofenac inhibits the synthesis of prostaglandins, which are responsible for causing pain, swelling and inflammation thus offers anti-inflammatory property.
Directions for Use
Interactions
Interactions with other medicines
- When Tolperitas Dsr Tablet is used along with another muscle relaxant medicine such as Methocarbamol can cause visual disturbances.
- Concurrent use of other painkillers such as niflumic acid and other NSAIDs increases the effect of Tolperitas Dsr Tablet.
- Tolperitas Dsr Tablet increases the effect of lithium (anti-anxiety medicine) and digoxin (heart failure medicine) when used concomitantly.
- Tolperitas Dsr Tablet might decrease the effectiveness of medicine used to lower blood pressure such as furosemide, enalapril and it can even lead to kidney damage.
- Medicine known to retain potassium level in the blood such as spironolactone, ciclosporin, tacrolimus or trimethoprim should be used with caution and monitored.
- Medicine used as a blood thinner such as warfarin should be used with caution as it can cause an increased risk of bleeding when used along with Tolperitas Dsr Tablet.
- Taking any other medicines containing Diclofenac or NSAIDs and citalopram, sertraline (mood enhancer) increases the risk of stomach or intestinal bleeding.
- Immunosuppressive medicine such as methotrexate, cyclosporine and tacrolimus effect increases and can cause kidney damage when used along with Tolperitas Dsr Tablet.
- Antimicrobials medicine like ciprofloxacin, lomefloxacin should be used with caution as it can cause fits.
- The phenytoin level should be monitored when taking it along with Tolperitas Dsr Tablet.
- Cholestyramine (lipid-lowering medicine) decreases the effect of Tolperitas Dsr Tablet when used along.
- Discuss with your doctor about any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.
Interactions with food items
Storage and disposal
- Store at a temperature below 30°C in a cool dry place.
- Keep out of the reach of children and pets.
Dosage
Overdose
- Excess of Tolperitas Dsr Tablet can cause symptoms such as headache, nausea, vomiting, chest pain, stomach or intestinal bleeding, diarrhoea, dizziness, excitation, coma, drowsiness, fainting or convulsions....
- However, if you have taken too much of Tolperitas Dsr Tablet then contact your doctor or reach out to the nearest hospital immediately.
Missed a Dose
Content Details

Dr. Arpit Verma
MBBS, MD CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can I take my regular painkillers along with Tolperitas Dsr Tablet?
Q: Is Tolperitas Dsr Tablet a painkiller?
Q: Is Tolperitas Dsr Tablet habit forming or addictive?
Q: Can Tolperitas Dsr Tablet be given to my 12-year-old kid for back pain?
References
- National insitute of pharmacy and nutrition. Merisone. 2025 [cited 12 June 2025] (online)
- PIL. Tolmus. 2025 [cited 12 June 2025] (online)
- EMA. SmPC. Diclofenac. 2025 [cited 12 June 2025] (online)
- CDSCO. Tolperisone/Diclofenac. 2025 [cited 12 June 2025] (online)
- Rao R, Panghate A, Chandanwale A, Sardar I, Ghosh M, Roy M, Banerjee B, Goswami A, Kotwal PP. Clinical comparative study: efficacy and tolerability of tolperisone and thiocolchicoside in acute low back pain and spinal muscle spasticity. Asian Spine J. 2012 Jun;6(2):115-22.[cited 21 Mar 2025].
- Kołodziejska J, Kołodziejczyk M. Diclofenac in the treatment of pain in patients with rheumatic diseases. Reumatologia. 2018;56(3):174-183.[cited 21 Mar 2025].
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