Septran 400/80 Mg Syrup 60 Ml

• If your child is allergic to sulfamethoxazole, trimethoprim or any other ingredient of Septran syrup.
• If your child is allergic to sulfonamides class of antibiotics.
• If your child has severe kidney disease or severe liver disease.
• If your child has a history of low platelet count with the use of trimethoprim and/or sulfonamides.
• If your child has acute porphyria.
• Septran syrup should not be given to infants upto 6 weeks old.

• Headache
• Nausea
• Diarrhoea
• Rashes
• Low potassium levels

Other General Warnings

• Your child has severe allergies, rashes or asthma.
• At the start of treatment, your child shows redness of skin with small bumps that contain fluid or pus.
• Your child develops conjunctivitis (red and swollen eyes) or ulcers in the mouth, throat, nose or genitals accompanied by flu-like symptoms.
• Your child has difficulty in breathing or develops unexpected worsening of cough.
• Your child is at risk of porphyria or is anaemic (low number of red blood cells), leukopenia (low number of white blood cells) or thrombocytopenic (low number of platelets).
• Your child has a glucose-6-phosphate dehydrogenase deficiency or has phenylketonuria.
• Your child has a glucose-6-phosphate dehydrogenase deficiency or has phenylketonuria.
• Your child is underweight or malnourished.
• Your child has high levels of potassium in his/her blood.
• Your child has any kind of kidney problems.

• Septran syrup should be given to your chlid as prescribed by the doctor
• Give the exact amount of liquid medication to your child as recommended by the doctor.
• Do not give more than the prescribed dose.

Overdose

Missed a Dose

How Does It Work?

• Sulfamethoxazole in Septran syrup inhibits the formation of a substance called dihydrofolate in the bacterial cell.
• Trimethoprim, also present in Septran syrup inhibits the chemical that converts dihydrofolate to tetrahydrofolate. Tetrahydrofolate is required by bacteria for the synthesis of many substances necessary for bacterial survival.
• Thus, this medicine inhibits the formation of tetrahydrofolate and prevents the growth and reproduction of bacteria.

Interactions with other medicines

• Some medicines can affect the way Septran syrup works or Septran syrup itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all medicines, supplements or herbals your child is currently taking or might take to avoid any possible interaction.
• Care should be taken if your child is taking zidovudine, cyclosporine, rifampicin, diuretics (thiazides), pyrimethamine, warfarin, phenytoin, digoxin, methotrexate, lamivudine, repaglinide, folinic acid or azathiprine.
• Septran syrup may interact with medicines that can cause low potassium levels in the body, like ACE inhibitors, angiotensin receptor blockers, potassium sparing diurecics (spironolactone) and should be used with caution for such combinations.