Pza Ciba 750mg Strip Of 15 Tablets
Pza Ciba 750 MG Description
Pza Ciba is a prescription antibiotic medication used in the management of tuberculosis. The active ingredient of Pza Ciba is Pyrazinamide 750 mg. Tuberculosis is a common infectious disease in In
dia. It is caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other organs like bones, spine, gastrointestinal tract, lymph nodes, meninges, etc. In lung tuberculosis, affected persons present symptoms of cough with sputum for more than two weeks, evening fevers, night sweats, and weight loss. If the disease affects other organs, the symptoms vary. Tuberculosis is a chronic, severely debilitating infection that requires sustained treatment. Pyrazinamide is part of the first-line medications used to treat tuberculosis, along with rifampicin, ethambutol, and isoniazid. Pza Ciba should only be given in combination with other anti-tubercular medicines. The medication should be taken only after consulting a doctor, and the directions for use of Pza Ciba tablets should be strictly followed. It should not be abruptly started or stopped. Taking the tablet at the same time every day is advisable. Side effects of Pza Ciba include tiredness, drowsiness, headache, dizziness, itching, skin rashes, loss of appetite, nausea, vomiting, abdominal pain, etc. It can also lead to an increase in uric acid levels and liver dysfunction.
Uses of Pza Ciba 750 MG
- Pza Ciba tablets are used in the treatment of tuberculosis.
Contraindications of Pza Ciba 750 MG
- Pyrazinamide is contraindicated:
- If you are hypersensitive to any of the components of this tablet.
- If you have acute liver disease, regardless of origin.
- If you have a history of medicine-induced liver dysfunction.
- If you have a history of gouty arthritis or increased uric acid levels.
- If you have a hereditary blood disorder called porphyria.
- If you have a history of rare disorders that affect galactose metabolism (galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption).
Side effects of Pza Ciba 750 MG
- Side effects of Pza Ciba include:
- Skin rashes
- Loss of appetite
- Abdominal pain
- Increase in uric acid levels (gout as a result requiring treatment and stoppage of the medicine. Gout presents as severe pain, redness, and swelling of joints.)
- Derangement of liver function tests
- Liver dysfunction (symptoms may include fever, generalised tiredness, right upper abdominal pain, jaundice, and enlargement of liver and spleen.
Precautions and Warnings of Pza Ciba 750 MG
Other General Warnings
- You take medicines for other conditions; it is important for the doctor to rule out any possible medicine interactions before prescribing this medicine.
- You notice a worsening of symptoms.
Mode of Action of Pza Ciba 750 MG
How Does It Work?
Directions for Use of Pza Ciba 750 MG
- Pza Ciba should be taken as prescribed by the treating physician.
- It is recommended to take this medication on a regular schedule. Taking the tablet at the same time every day is advisable.
- Swallow this medication as a whole. Do not crush, chew or break this tablet.
- This medication should be taken along with other anti-tubercular medications, as prescribed by the doctor.
- It is vital that the entire course of treatment is completed. Abrupt stoppage of the medicine can cause the recurrence of symptoms of the disease. Consult your doctor before stopping this medication.
- Pza Ciba can be taken with or without food.
- Inform your doctor regarding any other medication you take. Your doctor will review them to check for any potential medicine interaction associated effects.
Interactions of Pza Ciba 750 MG
Interactions with other medicines
- This medication decreases the effect of medicines used to treat gout, such as probenecid and sulfinpyrazone, which are uricosuric agents (increase the excretion of uric acid from the body).
- Pyrazinamide decreases the contraceptive effect of oestrogens.
- Oral typhoid vaccine might be inactivated by concomitant antibiotic administration.
Storage and disposal of Pza Ciba 750 MG
Dosage of Pza Ciba 750 MG
Missed a Dose
Frequently Asked Questions (FAQs)
Q: I have been experiencing joint pain since I started taking this medicine. Is this normal?
Q: I feel better after starting this medication. Can I stop it now?
Q: Will Pza Ciba affect my liver?
- PYRAZINAMIDE Tablet [Internet]. dailymed.nlm.nih.gov. 2022 [cited 25 February 2022]
- Zinamide Tablets: Summary of Product Characteristics (SmPC) - (emc) [Internet]. medicines.org.uk. 2022 [cited 25 February 2022] -
- Padda IS, Muralidhara Reddy K. Antitubercular Medications [Updated 25 Nov 2021]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 25 February 2022]
- Zhang Y, Shi W, Zhang W, and Mitchison D. Mechanisms of Pyrazinamide Action and Resistance. 2013. Microbiology Spectrum, 2(4): 1–12 [cited 25 February 2022] -
- National Center for Biotechnology Information. PubChem Compound Summary for CID 1046, Pyrazinamide [Internet] PubChem [cited 25 February 2022] -