Pyzina 1000mg Strip Of 10 Tablets
By LUPIN
10 Tablet(s) in Strip
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Description
Pyzina is a medication used in the treatment of tuberculosis (an infectious disease caused by a bacteria, mycobacterium tuberculosis, which primarily affects lungs but can also affect other organs).
Pyzina has a bactericidal action. It acts by killing the bacteria. It is used in combination with other medicines for the treatment of tuberculosis. It is well absorbed from the gastrointestinal tract and attains its maximum concentration in the blood after two hours of intake.
Product Summary
| Offer Price | ₹85.39 |
| You Save | ₹26.96 (24% on MRP) |
| Contains | Pyrazinamide(1000.0 Mg) |
| Uses | Tuberculosis |
| Side effects | Nausea, vomiting, stomach upset, fatigue, liver dysfunction. |
| Therapy | ANTI-TUBERCULAR |
Uses
- Pyzina is primarily used for the treatment of tuberculosis.
Contraindications
- Severe allergy to this medication is an absolute contraindication.
- If you have severe liver dysfunction.
- If you have severe kidney disease.
- If you have acute gout, it can worsen the condition.
Side effects
- Nausea
- Vomiting
- Liver dysfunction
- Muscle pain
- Joint pain
- Yellow discolouration of eyes
- Tiredness
- Skin rash
- Photosensitivity
Precautions and Warnings
Pregnancy
Q:
Can I take Pyzina during pregnancy?
A:
No fetal malformations have been found to be associated with Pyzina intake as per the data found, still you must consult your doctor before taking it during pregnancy.
Breast Feeding
Q:
Can I take Pyzina while breastfeeding?
A:
No. You should not, as this medicine is secreted in breast milk and can affect the health of a growing baby.
Driving
Q:
Can I drive if I have taken Pyzina?
A:
You can drive but avoid driving if you feel tiredness or weakness upon treatment with this medicine.
Alcohol
Q:
Can I consume alcohol with Pyzina?
A:
No. You should avoid the consumption of alcohol, as Pyzina and alcohol’s interaction can lead to liver dysfunction.
Other General Warnings
Talk to your doctor if
- You are taking medicines containing allopurinol and probenecid (for treatment of gout).
- You need to get your liver function tests done before taking this medicine. This medicine leads to liver dysfunction.
- You have to get your blood glucose levels regularly monitored or if you are a diabetic.
- You are getting excessive exposure to sunlight as it can lead to Photosensitivity.
- You are concomitantly using Pyzina with hormonal contraceptives as this can lead to contraceptive failure, so do not forget to tell your doctor if you are using both.
- You had an allergic reaction to any medication in the past (signs include rash, hives, shortness of breath, cough, wheezing etc.)
- Using this medication without rational evidence can lead to the development of resistance.
- Addition of foods rich in vitamin C help boost your immune system which can eventually help you fight the infection in a better way.
Mode of Action
How Does It Work?
Pyzina acts by activating an important enzyme (pyrazinamidase) which inhibits the synthesis of some important constituents of the cell membrane of the bacteria, which causes tuberculosis. One such constituent is an important fatty acid that helps maintain the integrity of the cell membrane of the bacteria. It hampers energy production important for the survival of the bacteria, i.e. mycobacterium tuberculosis....
Directions for Use
- Pyzina 1gm comes as an oral tablet formulation.
- It can be taken before or after meals.
- Swallow the tablet as a whole without crushing or breaking with a glass of water.
- Take it for as long as it is prescribed, do not interrupt the treatment before you are asked to do it.
- Don't use it if the packaging is damaged.
- Never try to increase or decrease the recommended dose as it can lead to toxicity or development of resistance against the medicine that can complicate the treatment and mandate the use of much stronger medicines....
Interactions
Interactions with other medicines
- Aceclofenac (an important painkiller) can decrease the excretion of Pyrazinamide that can lead to toxicity.
- Abacavir (antiviral medicine used for the treatment of AIDS) taken along with Pyrazinamide may decrease the excretion rate of Abacavir, resulting in a higher serum level and consequent toxicity.
- Paracetamol (important medicine for relieving fever and pain) may decrease the excretion of Pyrazinamide, leading to its toxic levels in the blood.
Interactions with food items
- Avoid having processed foods, sea food like tuna and salmon, and wine and beer.
Storage and disposal
Store this medicine away from direct sunlight and moisture.
Keep it beyond the reach of children and pets.
Do not flush the leftover medicine into the toilet.
Do not use the medication after the expiry date has passed....
Dosage
Overdose
Symptoms of overdose are nausea, vomiting, rash, itching, loss of consciousness. These symptoms can further lead to coma and death.
Call the emergency line as soon as possible or visit a nearby hospital at the earliest....
Missed a Dose
Take the missed dose as soon as possible.
Do not double the dose.
Take this medicine at fixed times in a day to avoid missing the dose.
Content Details
WRITTEN BY
Dr. Varsha Parihar
MBBS, MD (Community Medicine)
REVIEWED BY
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: Is Pyzina habit forming?
A: No. Pyzina is not a habit-forming medicine.
Q: Is it meant to be prescribed for kidney dysfunction?
A: It can be prescribed in mild kidney disorders but must be avoided in moderate to severe kidney disease.
Q: Can we give Pyzina to patients with acute gout?
A: No. It should not be given to people with acute gout as it can worsen the condition.
References
View All
- Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 415. ISBN 9781284057560.
- Pyrazinamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 29 January 2020]. Available from:
- DailyMed - Pyrazinamide tablet [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 29 January 2020]. Available from:
- Zinamide 500mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 29 January 2020]. Available from:
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Product Details
Brand
PYZINA
Country of Origin
India
Expiry Date
29/04/2027
Manufacturer Details
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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