Pph Tab

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Misoprostol(600.0 Mcg)
Therapeutic classification

Medical Description

PPH 600 MCG tablet is a prescription medication containing misoprostol. It is used for the prevention of NSAID (Non-Steroidal Anti-Inflammatory Medications) induced peptic ulcers, prevention of postpa...
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Uses of Pph 600 MCG

  • According to CDSCO, PPH 600 MCG tablets are used in the prevention of NSAID induced gastric ulcers.

Contraindications of Pph 600 MCG

  • Hypersensitivity to misoprostol, mifepristone or other prostaglandins
  • When used to prevent NSAID-induced ulcers, it is contraindicated in:
  • Inflammatory Bowel Disease
  • Pregnancy, as it can cause rupture of the uterus and can be life-threatening.
  • When used to prevent Postpartum Haemorrhage, it is contraindicated in:
  • Patients who have previously undergone a Caesarean Section.
  • When used for termination of pregnancy, it is contraindicated in:
  • Confirmed/Ectopic pregnancy
  • Intrauterine device in place
  • Undiagnosed pelvic mass
  • Bleeding disorders

Side effects of Pph 600 MCG

  • Nausea
  • Abdominal & pelvic cramps
  • Fever & chills
  • Vomiting
  • Fatigue
  • Diarrhoea

Precautions and Warnings of Pph 600 MCG


Can I take PPH 600 MCG Tablets during pregnancy?
This medication should not be used during pregnancy and is contraindicated. It can cause congenital anomalies and is labeled as a category X medication.

Breast Feeding

Can I take PPH 600 MCG Tablets while breastfeeding?
This medication is not advisable to be taken while breastfeeding. It can potentially cause diarrhea in the newborn infant.


Can I drive if I have taken a PPH 600 MCG Tablet?
Driving is not contraindicated as long as the patient is not experiencing severe bleeding manifestations or other mentioned side effects.


Can I consume alcohol with the PPH 600 MCG Tablets?
Limit alcohol consumption while on this medication.

Other General Warnings

Talk to your doctor if
  • You are pregnant or planning a pregnancy prior to starting this medication.
  • You experience severe bleeding while taking this medicine.
  • You have been given this tablet for the medical termination of a pregnancy. This tablet cannot be used after eight weeks of pregnancy as it can be potentially life-threatening.

Mode of Action of Pph 600 MCG

How Does It Work?

The pharmacological component of PPH 600 MCG tablets is a medication called Misoprostol. Misoprostol is a prostaglandin E1 analog, meaning It is similar to a chemical produced in the body known as Pro...
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Directions for Use of Pph 600 MCG

  • Always take with a meal.
  • Swallow tablet whole, do not split, crush, or chew
  • Take this medication at the recommended dose. Do not alter the dose as it may result in increased bleeding and other side effects.
  • Take this medication in an appropriate setting with access to your doctor/hospital as you may begin to experience side effects that require immediate intervention like increased pain, severe bleeding,...
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  • In order to check if complete termination of pregnancy has taken place, review with your treating doctor 7 days following the use of this medication.
  • Do not take this medication if you have a history of ectopic pregnancy or an IUD in place.

Interactions of Pph 600 MCG

Interactions with other medicines

  • Co-administration with Magnesium containing Antacids is not recommended as they can reduce the blood level of the medication.
  • Co-administration with oxytocin is not recommended as it augments its actions.

Interactions with food items

  • This medication does not interact with any food item.

Storage and disposal of Pph 600 MCG

Store below 25°C. Store in a cool and dry place away from direct light and moisture. Do not use the medicine after the date of expiration. Keep the tablets away from children and pets. Do not fl...
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Dosage of Pph 600 MCG


Overdose with this medication can result in severe bleeding and infections. In case of a suspected overdose, rush the patient to a tertiary care hospital for emergency intervention and management.

Missed a Dose

In case of a missed dose, review with your doctor for further advice. Do not double the dose of this medication.

Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: I was prescribed this tablet by my doctor. After starting it, my period was delayed. Should I stop taking the tablet?

A: PPH 600 MCG tablets can cause menstrual irregularities. However, it is important to consult your doctor at the earliest. Do not abruptly start or stop using the tablet.

Q: I have a fever after taking this tablet. What should I do?

A: Fever is a common side effect of PPH 600 MCG tablets when used for the prevention of NSAID-induced gastric ulcers. Consult your doctor before taking any medicine for this. NSAIDs are commonly used to treat fever, and these may worsen gastric ulcers.

Q: It has been 24 hours since I took this medication, but I do not see any effects. Should I take another dose?

A: This medication can take up to 24-48 hours to take effect. Take this medication as recommended by your doctor. Do not increase the dose without the prescription of your treating physician.
Product Details
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Quick Summary

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ContainsMisoprostol(600.0 Mcg)
UsesPrevention of NSAID induced peptic ulcers, prevention of postpartum haemorrhage, and termination of early pregnancy.
Side effectsIncreased bleeding, abdominal pain, uterine cramping, nausea, vomiting, and diarrhoea
Last Updated on: 04 Mar 2022 | 04:53 PM (IST)
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