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Phenytal 30mg Strip Of 10 Tablets

10 Tablet(s) in Strip
We do not sell this product

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INTAS PHARMACEUTICALS LTD

Dosage

TABLET

Expiry

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Product Summary

Salt Content
Phenytoin(100.0 Mg)+Phenobarbital(30.0 Mg)
Uses
Treatment of seizure disorders
Therapy
Anti-epileptic
Side effects
Skin rashes, Peripheral neuropathy, Abnormal eye movements (nystagmus), Sedation, Drowsiness, Nausea, Vomiting, Constipation, Liver damage, Decrease in blood cell counts, Swelling of gums, Low blood pressure
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available
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Medical Description

Phenytal is a prescription medication used to manage seizure disorders. It is a combination of two medications at fixed doses, Phenytoin and Phenobarbital. Seizures occur due to abnormal, uncontrolled electrical activity in the brain and can have many symptoms. Some of these symptoms can include abnormal movements, loss of consciousness, uprolling of eyes, loss of control of urination and defecation etc. Seizure disorders may require long term treatment with anticonvulsants. Phenytoin is an anti-convulsant, and Phenobarbital is a sedative-hypnotic that belongs to a group of medicines called Barbiturates. They both act by different mechanisms to decrease seizures in patients with epilepsy. Phenytal should be taken as recommended by the doctor. It should not be abruptly started or stopped, as it may cause seizures and withdrawal effects. Taking Phenytal tablets at the same time every day is advisable for maximum efficacy.

Uses

  • Seizure disorders
  • Prevention and control of seizures following trauma, and neurosurgery

Contraindications

  • If you have known phenytoin or phenobarbital hypersensitivity or known allergies to any components in this medication.
  • If you have a history of suicidal thoughts and behaviour.
  • If you have liver or kidney dysfunction.
  • If you have respiratory insufficiency.
  • If you have congenital blood dyscrasias known as porphyrias.
  • If you have rare disorders of galactose metabolism, like galactose intolerance, total lactase deficiency or glucose-galactose malabsorption.

Side effects

  • Skin rashes
  • Peripheral neuropathy – presents as weakness, numbness and pain of hands and feet
  • Abnormal eye movements (nystagmus)
  • Sedation, drowsiness
  • Nausea, vomiting
  • Constipation
  • Liver damage
  • Swelling of gums
  • Low blood pressure

Precautions and Warnings

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Pregnancy

Phenytal is contraindicated in pregnancy. It is known to produce fetal abnormalities. It shouldn’t be given during pregnancy or prior to conception. Inform your doctor about your pregnancy or intention to conceive.

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Breast Feeding

Phenytal is not recommended during breastfeeding as it can be transferred via breast milk.

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Driving

Phenytal can cause drowsiness, sedation, agitation and other neurological side effects. Driving and use of heavy machinery are not recommended.

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Alcohol

Mixing alcohol and other CNS depressants with Phenytal can lead to increased sedation, respiratory depression, coma and even death. It is strictly contraindicated.

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Other General Warnings

Talk to your doctor if
  • You are on any other medications.
  • You are taking Phenytal during the evaluation of other conditions.
  • You have any suicidal ideation, worsening of mood, or seizures.

Directions for Use

  • Phenytal should be taken as prescribed by your doctor.
  • It’s recommended to take Phenytal medication on a regular schedule, i.e., at the same time every day.
  • Swallow this medication as a whole. Don’t crush, chew or break this tablet.
  • It’s recommended to finish the full course of this medication as prescribed by your treating doctor.
  • Abrupt stoppage of Phenytal can cause seizures and withdrawal side effects. Consult your doctor before stopping this medication.
  • This medication has habit-forming tendencies; hence it is recommended to follow the directions of your treating physician precisely and have a regular follow-up.

Storage and disposal

Store Phenytal in a cool and dry place away from direct light and moisture. Do not use the medicine after the date of expiration. Keep Phenytal tablets away from children and pets. Do not flush the medication down the toilet. Dispose of it with biomedical waste only.

Dosage

Overdose

Overdose with these medications presents with neurological symptoms primarily like drowsiness, inability to articulate speech, ataxia, nystagmus and disinhibition. There may also be coma, cardiovascular collapse, cardiac arrest, decreased BP, poor tone, loss of reflexes, hypothermia, respiratory depression and even death. In case of a suspected overdose, rush the patient to an emergency centre for further evaluation and treatment.

Missed a Dose

If you miss a dose of Phenytal tablet, it is advised to take it just when you remember. If the period missed is too long, and it's almost time for the next dose, it's recommended to skip the missed dose and return to the regular schedule. Don't double the dose of the tablet.

Mode of Action

How Does It Work?

Both Phenytoin and Phenobarbital are central nervous system (CNS) depressants, i.e., they decrease neuronal activity in the brain. This helps treat seizures. Phenytoin is an anti-convulsant. It primarily acts on sodium channels in brain cells to reduce the transmission of signals, thereby preventing abnormal electrical activity during seizures without significantly impairing neurological functions. Phenobarbital is a sedative-hypnotic that belongs to the class of Barbiturate medications. It acts by affecting a chemical receptor called GABA-A to increase chloride levels, making the nerve cell less capable of transmitting abnormal signals. This prevents seizure activity. Phenobarbital, being a barbiturate, has addictive, misuse and abuse potential. Patients using this medication as an anti-convulsant should be closely monitored.

Interactions

Interactions with other medicines

  • Phenytoin and Phenobarbital are both known inducers of certain liver enzymes and can accelerate the metabolism of several medicines, resulting in decreased efficacy.
  • Phenobarbital decreases the efficacy of Oral Contraceptive Pills, and alternate contraceptive measures should be used.
  • The concomitant use of this medication with opioids (like morphine, tramadol etc.) is contraindicated, as it may cause respiratory depression, coma and death.
  • It should also not be used with other CNS depressants like alcohol can also cause similar effects and present life-threatening adverse effects.
  • Inform your doctor regarding your current medicines at the time of prescription of Phenytal.

Interactions with food items

  • Phenytal does not have any known interaction with food items.

Frequently Asked Questions (FAQs)

Phenytal is known to cause fetal abnormalities. If you have been taking Phenytal regularly, inform your doctor. It is recommended to stop this medication at least two months prior to conception. It is recommended to use contraceptive methods for two months after stopping Phenytal.

Peripheral neuropathy, which presents as weakness, abnormal or decreased sensations, and pain of hands and feet, is a side effect of Phenytal. Inform your doctor for more information on managing side effects. Do not stop taking Phenytal without the express recommendation of your doctor.

Phenytal can reduce the efficacy of oral contraceptive pills. It is not recommended to take them together. Consult your doctor for guidance on which contraceptive method to opt for.

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Manufacturer Details

Brand:PHENYTAL

Manufacturer Name:INTAS PHARMACEUTICALS LTD

Address:<p>1. Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.</p>

Country of Origin:India

Vendor Details

Fulfillment Information: Phenytal 30mg Strip Of 10 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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