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Paxidep Cr 37.5mg Tablet

10 Tablet(s) in Strip
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Paxidep Cr 37.5 MG Description

Paxidep Cr 37.5 mg tablet is a prescription medicine used to treat Major Depressive Disorder, Obsessive-Compulsive Disorder (OCD), and other anxiety disorders such as Social Anxiety Disorders (SAD),

Generalised Anxiety Disorder (GAD), and Post-Traumatic Stress Disorder (PTSD). The active ingredient in Paxidep Cr 37.5 mg tablet is Paroxetine, an antidepressant class of medicines. The mode of action of Paxidep Cr tablet is by preventing the reuptake of the neurotransmitter serotonin, a chemical messenger between nerve cells. An increase in serotonin concentration helps with sedation, anxiety, and muscle relaxation leading to an improved mental state. Directions for use of Paxidep Cr 37.5 mg tablets should be strictly followed. It takes approximately 4-6 weeks for Paxidep Cr tablets to attain full potential. This tablet should not be used with alcohol and should be taken only in the recommended dose. This medicine can increase suicidal tendencies and ideation in users, especially adolescents and young adults. It is, therefore, recommended to be in close contact with the consulting doctor for the entire course of treatment. Side effects of Paxidep Cr 37.5 mg tablets include difficulty maintaining sleep, nausea, loose motions, headaches, lethargy, sexual dysfunction, and drowsiness.


Product Summary

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ContainsParoxetine(37.5 Mg)
UsesMajor Depressive Disorder, Obsessive-Compulsive Disorder (OCD), Social Anxiety Disorders (SAD), Generalised Anxiety Disorder (GAD), Post-Traumatic Stress Disorder (PTSD)
Side effectsDifficulty in maintaining sleep, Nausea, Loose motions, Headaches, Lethargy, Sexual dysfunction, Drowsiness
Check more medicines with composition as Paroxetine(37.5 Mg)

Uses of Paxidep Cr 37.5 MG

  • According to CDSCO, Paxidep Cr tablet is used in the treatment of:
  • Major Depressive Disorder
  • Obsessive-Compulsive Disorder (OCD)
  • Panic Disorder
  • Post-Traumatic Stress Disorder
  • Generalised Anxiety Disorder

Contraindications of Paxidep Cr 37.5 MG

  • Paxidep Cr tablets should be avoided:
  • If you are allergic to paroxetine.
  • If you recently had a heart attack.
  • If you have low sodium levels.
  • If you have glaucoma.
  • If you are pregnant.
  • If you have any bleeding disorders.
  • If you have seizures (fits).
  • If you have any bone fractures.

Side effects of Paxidep Cr 37.5 MG

  • Side effects of Paxidep Cr tablets include:
  • Drowsiness
  • Difficulty in maintaining sleep
  • Loose motions
  • Headaches
  • Lethargy
  • Sexual dysfunction
  • Nausea

Precautions and Warnings of Paxidep Cr 37.5 MG



Can I take Paxidep Cr tablets during pregnancy?
You should avoid taking this tablet if you are pregnant. This medicine can cause congenital disabilities such as pulmonary hypertension in your infant. If you get pregnant while already on Paxidep Cr tablets, do not suddenly stop the medicine. It may cause withdrawal symptoms such as muscle aches, confusion, depression, dizziness, headaches, irritability. Consult your doctor at the earliest. Do not continue taking this medicine throughout your pregnancy unless advised by your doctor.

Breast Feeding

Can I take Paxidep Cr tablets while breastfeeding?
This tablet may be safe to take by nursing mothers after consulting with a doctor. If your infant exhibits symptoms such as difficulty sleeping, irritability, poor feeding, and excessive crying, consult your doctor immediately.


Can I drive if I have taken a Paxidep Cr tablet?
Avoid this tablet while driving as it may decrease your judgement and impair your motor skills.


Can I consume alcohol with Paxidep Cr tablets?
Avoid using alcohol when on treatment with Paxidep Cr tablets. Mixing them may worsen your symptoms and cause irritability, agitation, lethargy, confusion, motor incoordination, and, in some cases, difficulty breathing.

Other General Warnings

Talk to your doctor if
  • You have chest pain after taking this tablet.
  • You have suicidal or self-harming thoughts.
  • You have sexual problems.
  • You have excessive bleeding or cannot stop bleeding from any cuts.
  • You have difficulty breathing.
  • You experience bloody vomiting or notice blood in the urine.
  • You feel confused or disoriented.

Mode of Action of Paxidep Cr 37.5 MG

How Does It Work?

Paxidep Cr tablet prevents the reuptake of serotonin, a neurotransmitter or brain chemical between nerve cells. Increased concentration between them is responsible for sedation, anxiety, and muscle re...
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Directions for Use of Paxidep Cr 37.5 MG

  • Take Paxidep Cr tablets exactly as advised by your doctor.
  • Do not exceed the dosage, even if you cannot notice the effects of this medicine.
  • Swallow the Paxidep Cr tablet with a glass of water.
  • Take this medicine at the same time every day.
  • Check the expiration date on the package and do not consume expired medicine.
  • Do not consume the tablets if their packaging is broken.

Interactions of Paxidep Cr 37.5 MG

Interactions with other medicines

  • Paxidep Cr tablets may interact with certain medicines. It is critical to inform the treating doctor about any other medications being taken.
  • Paxidep Cr tablets can cause Serotonin Syndrome when co-administered with:
  • Antidepressants like phenelzine and selegiline
  • Antibiotics like linezolid
  • Antipsychotics like thioridazine
  • Medicines like pimozide used to control abnormal movements
  • Strong painkillers like tramadol, fentanyl, and methadone
  • Blood thinners like aspirin, clopidogrel, heparin, and warfarin can increase the risk of bleeding.
  • Antivirals like ritonavir and fosamprenavir can decrease paroxetine levels in the body.

Storage and disposal of Paxidep Cr 37.5 MG

Store Paxidep Cr tablets in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the tab...
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Dosage of Paxidep Cr 37.5 MG


Paxidep Cr tablet overdose can lead to drowsiness, fits, muscles aches, loose motions, dark red urine, excitement, irritability, and agitation. Keep your family or caregiver updated on your medication...
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Missed a Dose

If you have missed a single dose of Paxidep Cr tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue w...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: Can I suddenly stop taking Paxidep Cr tablets?

A: Do not abruptly stop taking this tablet as it may cause withdrawal symptoms such as muscle aches, confusion, depression, dizziness, headaches, irritability, and anxiety.

Q: Will I immediately feel better after starting treatment with Paxidep Cr tablets?

A: Your symptoms may start to improve clinically after one or two weeks of treatment. However, it typically takes 4-6 weeks for this medicine to show its full efficiency.

Q: Will I experience weight change after starting treatment with Paxidep Cr tablets?

A: Paroxetine suppresses appetite, so you may lose weight when you start taking this medicine. As your hunger returns, you may gain a little weight later.
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Last Updated on: 14 Mar 2022 | 10:03 AM (IST)
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