Neotrexate 5mg Strip Of 10 Tablets
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10 Tablet(s) in Strip
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Neotrexate 5 MG Description
Neotrexate 5mg Tab is a medicine that contains methotrexate. It helps slow down the growth and multiplication of cancer cells and suppresses the immune system.
Product Summary
| Offer Price | ₹57.00 |
| You Save | |
| Contains | Methotrexate(5.0 Mg) |
| Uses | psoriasis, rheumatoid arthritis and various types of cancers |
| Side effects | headache, dizziness, fatigue, leucopenia, infections, inflammation and sores inside the mouth |
| Therapy | ANTI-NEOPLASTIC |
Check more medicines with composition as Methotrexate(5.0 Mg)
Uses of Neotrexate 5 MG
- Psoriasis
- Rheumatoid arthritis
- Various types of cancers
Contraindications of Neotrexate 5 MG
- Allergy to the active substance or any of the excipients
- Significantly impaired liver function
- Severe/significantly impaired kidney function
- Liver diseases including fibrosis, cirrhosis, recent or active hepatitis
- Active infectious disease
- Pre-existing blood dyscrasias, such as bone marrow hypoplasia, significant anaemia, thrombocytopenia or leucopenia
- Severe acute or chronic infections and immunodeficiency syndrome
Side effects of Neotrexate 5 MG
- Headache
- Dizziness
- Fatigue
- Leucopenia
- Infections
- Anorexia
- Nausea
- Diarrhoea
- Elevated transaminase concentrations
- Inflammation and sores inside the mouth
- Temporary hair loss
Precautions and Warnings of Neotrexate 5 MG
Pregnancy
Q:
Is it safe to use Neotrexate 5mg Tablet during pregnancy?
A:
Neotrexate 5mg Tablet should not be used during pregnancy as its active component, methotrexate, has shown to cause congenital abnormalities, foetal death, or even miscarriages. Therefore, methotrexate is contraindicated during pregnancy.
Breast Feeding
Q:
Can I use Neotrexate 5mg Tablet during breastfeeding?
A:
Methotrexate passes into breast milk in small amounts and may cause toxicity in infants. Therefore, treatment is contraindicated during breastfeeding, or breastfeeding should be temporarily stopped.
Driving
Q:
Can I drive if I have taken Neotrexate 5mg Tablet?
A:
Methotrexate can cause fatigue, blurred vision, and dizziness, affecting your driving ability. Do not drive if any of these symptoms are seen.
Alcohol
Q:
Can I consume alcohol with Neotrexate 5mg Tablet?
A:
It is recommended to avoid alcohol during medication as it may intensify the side effects.
Other General Warnings
Talk to your doctor if
- You have diabetes mellitus
- You have cardiac failure
- You have acute pancreatitis
- You have hypoglycaemia
- You are galactose intolerance
- You have anaemia
- You are above the age of 65
- You have psoriasis or other skin condition
- You have kidney or liver problems
- You are allergic to the active substance or any of the excipients
- You are taking herbal medications, nutritional supplements, vitamins or minerals
Mode of Action of Neotrexate 5 MG
How Does It Work?
Methotrexate belongs to the class of medications known as antimetabolites. It inhibits the growth and multiplication of cells slowing the growth of cancer cells. In psoriasis, methotrexate works by a similar mechanism and prevents scale formation. Methotrexate reduces immune system activity, lowering pain, stiffness, and swelling in rheumatoid arthritis....
Directions for Use of Neotrexate 5 MG
- Take this tablet for the dose and duration prescribed by your physician
- Do not break, chew or crush this tablet
- Swallow the tablet with a glass of water
Interactions of Neotrexate 5 MG
Interactions with other medicines
- Concurrent treatment with live vaccine and methotrexate may lead to severe antigenic reactions
- Concomitant use of general anaesthesia may increase the antifolate effect of methotrexate
- Concomitant use of antipsychotics increases the risk of agranulocytosis
- The risk of hepatotoxicity increases with the simultaneous use of retinoids
- Co-administration with NSAIDs may increase and prolong serum methotrexate concentrations
- Concomitant use of sulfamethoxazole and folate antagonists increases the risk of haematological toxicity
- Concomitant use of loop diuretics reduces the excretion of methotrexate, thereby increasing the risk of toxicity
- Neomycin, when co-administered with methotrexate, reduces the absorption of methotrexate
Storage and disposal of Neotrexate 5 MG
- Keep it in a cool and dry place away from sunlight and moisture
- Keep the medication away from the reach of children and pets
- Do not flush the unneeded or expired tablets
- Talk to your doctor or pharmacist about the safe way of discarding the tablets
Dosage of Neotrexate 5 MG
Overdose
In case of overdose, if you have trouble breathing or feel nauseated you should contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you forget to take a dose, take it as soon as you remember. If the next dose is approaching, skip the missing dose. Instead, use your next dose at the same time every day. Do not take two tablets at once....
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Frequently Asked Questions (FAQs)
Q: Can Neotrexate 5mg tablets be given to a pediatric patient?
A: Neotrexate 5mg tablets should not be given to children as the safety and effectiveness of this medication have not been established yet, other than in chemotherapy.
Q: Apart from the oral route, what are the different ways of administration for methotrexate?
A: Methotrexate can be administered by intramuscular, intravenous, intrathecal (into the spinal cord), and intra-arterial routes directly into the arteries.
Q: What should I tell my doctor before starting the Neotrexate 5mg tablet?
A: You should give detailed information about your medical and surgical history and allergies. You should also inform the doctor about your current diseases like hypertension, kidney problems, etc., and your current medication.
Q: Will Neotrexate 5mg tablets affect my fertility?
A: Neotrexate 5mg tablets may decrease fertility in both men and women; it may lower the sperm count and cause menstrual disturbances; however, these effects can be reversed after discontinuation of methotrexate in most cases.
References
- Methotrexate 2.5 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 19 April 2022]. Available from: https://www.medicines.org.uk/emc/product/511#gref
- Methotrexate: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 19 April 2022]. Available from: https://medlineplus.gov/druginfo/meds/a682019.html
Product Details
Brand
NEOTREXATE
Expires on or After
24/02/2025
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