Meroza Xp Injection
Description
Meroza Xp injection is used in hospitals to treat serious infections, such as complicated skin infections, abdominal infections, and meningitis, in children. It is only used when the infection is likely caused by bacteria that this medicine can fight, to prevent antibiotic resistance. Your doctor or nurse will administer this injection, so please do not attempt to use it yourself.
Meropenem works by breaking down the protective walls of bacteria, causing them to die. Sulbactam helps meropenem work better by blocking enzymes made by some bacteria that can destroy antibiotics. While sulbactam doesn’t work on its own, it boosts the overall effect of the treatment when combined.
Do not take this medicine if you are allergic to meropenem, sulbactam, or any similar antibiotics like penicillin. Common side effects include injection site inflammation, nausea, diarrhoea, headache, or skin rash. Let your doctor know if you are pregnant, breastfeeding, or have kidney problems, seizures, or a history of allergic reactions.
Some medications, such as valproic acid and probenecid, can interact with how meropenem or sulbactam works. The medicine should be stored at a temperature below 25°C and kept away from light and heat. Since this injection is given by a healthcare professional, overdoses or missed doses are rare. Tell your doctor if you feel unwell, have severe diarrhoea, or develop new symptoms during or after treatment.
Product Summary
Offer Price | ₹499.32 |
You Save | ₹157.68 (24% on MRP) |
Contains | |
Uses | Antibacterial |
Side effects | Inflammation at the injection site, diarrhoea, nausea or vomiting, headache |
Therapy | ANTIBIOTIC |
Uses
Contraindications
- If you are allergic to meropenem, sulbactam or any other ingredients of Meroza Xp injection.
- If you have a history of a severe allergic reaction to any other antibiotics, such as penicillins.
Side effects
- Inflammation at the injection site
- Diarrhoea
- Nausea or vomiting
- Headache
- Rash
Precautions and Warnings
Pregnancy
- It can be prescribed to you by your doctor if necessary, after a careful assessment of the benefits against the risks.
- Consult your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a history of allergies to penicillin or similar antibiotics, as you may be at risk for a serious allergic reaction.
- You have kidney problems, seizures, epilepsy, or are taking valproic acid, as this medication may increase seizure risk or interact with your current treatment.
- You develop diarrhoea during or after treatment, as it could be a sign of a serious intestinal infection.
- You are pregnant, have issues with sodium or fluid balance, or if your child is receiving this medication, to ensure safe use.
- Your symptoms worsen or new ones appear, as prolonged antibiotic use can lead to the development of resistant or new infections.
- You feel confused, dizzy, or experience tremors or tingling, and avoid driving or using machines until you know how the medicine affects you.
Directions for Use
- Meroza Xp injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
Storage and disposal
- Store this medicine at a temperature of 25 °C or below.
- Protect it from light and heat.
- Keep it out of the reach of children and pets.
- Any unused portion should not be stored and discarded properly.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Meropenem is a powerful antibiotic that kills bacteria responsible for serious infections. It works by preventing the bacteria from building their protective outer wall, which is essential for their survival. Without this wall, the bacteria break apart and die, aiding your body in fighting the infection more effectively....
- Sulbactam is a medication that enhances the effectiveness of certain antibiotics by preventing bacteria from breaking them down. Some bacteria produce special enzymes that can render antibiotics ineffective, thereby reducing the effectiveness of treatment. Sulbactam blocks these enzymes, so the antibiotic can do its job and kill the bacteria. On its own, sulbactam doesn't treat infections, but when combined with other antibiotics, it helps treat tough bacterial infections more effectively....
Interactions
Interactions with other medicines
- Taking probenecid with meropenem can raise the level of meropenem in your blood, so using them together is not recommended.
- If you are taking valproic acid (a seizure medicine), adding meropenem may lower its levels in your blood, which can raise the risk of having seizures. Extra seizure medicine may be needed if meropenem must be used....
- Sulbactam may interact with a group of antibiotics called aminoglycosides (such as tobramycin, amikacin, and gentamicin), especially at high concentrations in laboratory studies. However, this interaction is unlikely to occur in the body at normal doses....
- Taking sulbactam with probenecid can slow the rate at which sulbactam is eliminated from your body.
- Some possible interactions reported with sulbactam may actually be due to the other antibiotic it's combined with, rather than sulbactam itself.
Content Details

Ravindra Ghongade
B. Pharm

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: Can this injection be used to treat COVID-19 or viral infections?
Q: Are there any dietary restrictions during treatment?
References
- Merrem (meropenem) injection [package insert]. Silver Spring (MD): U.S. Food and Drug Administration; 2016 Dec 12 [cited 2025 Jun 30].
- Biocon Ltd. Matabac (sulbactam sodium) injection: prescribing information [Internet]. Bangalore (India): Biocon Ltd; [date unknown; cited 2025 Jun 30].
- Central Drugs Standard Control Organisation. Drugs [Internet]. New Delhi: Ministry of Health and Family Welfare, Government of India; [cited 2025 Jun 30].
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