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Macox Plus 600/300mg Tablet

6 Tablet(s) in Strip
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Macox Plus 600/300mg Tablet Description

Macox Plus Tablet is used for the treatment of tuberculosis, a bacterial infection that mainly affects the lungs. The tuberculosis bacterial infection may spread to organs other than the lungs, such

as the abdomen, kidney, skeletal muscles, spine, and brain. Macox Plus Tablet belongs to a class of medicines called antibacterials (medicines that kill bacteria). Its active ingredients are isoniazid and rifampicin. You should take Macox Plus Tablet as prescribed by your doctor. The duration and dose of Macox Plus Tablet vary depending on the patient’s condition and age. It is important to complete the prescribed course of Macox Plus Tablet to prevent reinfection and development of medicine resistance in TB bacteria. Side effects of Macox Plus Tablets include upset stomach, diarrhoea, fever, and rash. You must consult your doctor before starting treatment with Macox Plus Tablet and understand its potential side effects and benefits. Macox Plus Tablet interaction with alcohol and certain nutritional supplements may produce adverse effects and must be avoided. Macox Plus Tablet may also interact and produce life-threatening side effects with certain medications used in anxiety, epilepsy, Parkinson’s, HIV, or fungal infection.


Product Summary

Offer Price₹69.27
You Save₹12.23 (15% on MRP)
ContainsRifampicin(600.0 Mg) + Isoniazid(300.0 Mg)
Side effectsUpset stomach, diarrhoea, fever, eye pain, sore throat
Check more medicines with composition as Rifampicin(600.0 Mg) + Isoniazid(300.0 Mg)

Uses of Macox Plus 600/300mg Tablet

  • Macox Plus Tablet is used in,
  • Treatment of pulmonary tuberculosis (a bacterial infection that mainly affects lungs causing coughing for three or more weeks along with fatigue and chest pain or difficulty in breathing)
  • Treatment of extra-pulmonary tuberculosis (tuberculosis may also affect organs other than lungs such as stomach (abdomen), skeletal muscles, spine, lymph glands, kidney, and brain)

Contraindications of Macox Plus 600/300mg Tablet

  • If you are allergic to Isoniazid or Rifampicin or any of the ingredients present in the medicine.
  • If you have or had any serious liver problems.

Side effects of Macox Plus 600/300mg Tablet

  • Upset stomach
  • Diarrhoea
  • Fever
  • Rash
  • Sore Throat
  • Eye Pain

Precautions and Warnings of Macox Plus 600/300mg Tablet



Can I take Macox Plus Tablet during pregnancy?
No, Macox Tablet is not safe to be taken during pregnancy as it may cause problems in the newborn when taken during pregnancy. Consult your doctor before starting any medicine if you are planning a pregnancy or are pregnant.

Breast Feeding

Can I take Macox Plus Tablet while breastfeeding?
Macox Tablet gets excreted in breast milk, so avoid taking it if you are breastfeeding. If you take Macox Tablet while breastfeeding and notice your child sleeping more than usual or is facing any breathing difficulty, or is not able to suckle, immediately consult your doctor.


Can I drive if I have taken Macox Plus Tablet?
No, it is not safe to drive when taking Macox Plus Tablet as it is known to cause eye pain, vision problems, and numbness or tingling sensation in the hands and feet that may affect your driving abilities.


Can I consume alcohol with the Macox Plus Tablet?
No, alcohol must be avoided with Macox Plus Tablet as it causes liver damage which can be fatal.

Other General Warnings

Talk to your doctor if
  • You drink alcohol regularly.
  • You have epilepsy (seizures) or ever had fits.
  • You have diabetes.
  • You have or ever had serious liver or kidney problems.
  • You are suffering or have suffered from mental problems such as hallucinations (seeing or hearing things that are actually not present).
  • You are malnourished (weight is below normal and have nutrition deficiencies).
  • You have an HIV infection.
  • You conceive during the course of Macox Plus Tablet or are planning a pregnancy.

Mode of Action of Macox Plus 600/300mg Tablet

How Does It Work?

Macox Plus Tablet belongs to a class of medicines called antibacterials (medicines that kill bacteria) with isoniazid and rifampicin as active ingredients. Isoniazid and rifampicin act by killing bact...
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Directions for Use of Macox Plus 600/300mg Tablet

  • Macox Plus Tablet must be taken as per doctor’s prescription.
  • Macox Plus Tablet must be taken without food.
  • Make sure to swallow the Macox Plus Tablet as a whole and do not chew, crush or break it.
  • Macox Plus Tablet must be taken at the same time as per prescription to ensure better efficacy and benefits.

Interactions of Macox Plus 600/300mg Tablet

Interactions with other medicines

  • Avoid taking Macox Plus Tablet with the following medicines as it may reduce their effectiveness:
  • Medicines used for the treatment of fungal infections (ketoconazole)
  • Medicines for the management of anxiety (diazepam)
  • Medicines for the treatment of Parkinson’s disease (levodopa)
  • Macox Plus Tablet should not be taken along with the following medicines as it increases their toxicity and adverse effects:
  • Medicines used in the treatment of epilepsy (carbamazepine, phenytoin)
  • Medicines used in the treatment of HIV (stavudine)
  • Medicines for the treatment of alcohol addiction (disulfiram)
  • Inform your doctor about all medicines and supplements you are currently taking to prevent side effects associated with drug interaction.

Interactions with food items

  • Macox Plus Tablet may interact adversely with tyramine or histamine containing foods and beverages (cheese, red wine, beer, tuna fish, salmon and other tropical fish).

Storage and disposal of Macox Plus 600/300mg Tablet

Macox Plus Tablets must be stored in a dry place, away from sunlight, at room temperature. It should be kept away from the reach of children. It must be disposed of as biomedical waste so that it ...
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Dosage of Macox Plus 600/300mg Tablet


Symptoms of an overdose of Macox Plus Tablet may include nausea (feeling sick), vomiting, dizziness, speech, and vision problems. If you happen to take too much of the Macox Tablet, reach out to yo...
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Missed a Dose

Take the missed dose of Macox Plus Tablet as soon as you remember. Skip the missed dose if enough time has passed and it is time for your next scheduled dose. Do not take a double dose of Macox Plus T...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can I give Macox Plus Tablets to children?

A: Macox Plus Tablets are not meant to be given to children under 3 years of age. You should not give this medicine to children without consulting with your doctor.

Q: I have been taking Macox Plus Tablets for a week now but do not see much improvement in my condition. Should I stop taking it?

A: No, you should not stop taking Macox Plus Tablets suddenly without consulting your doctor as it may cause symptoms of withdrawal like headache, sleeping problems, irritation, nervousness, and uncontrollable dreams. If you stop taking Macox Plus Tablets before the prescribed duration is over, the bacteria may develop resistance to this medicine (the medicine will become ineffective when taken in future). Hence, you should consult your doctor before stopping this medicine.

Q: What other precautions should I take while taking Macox Plus Tablets?

A: Macox Plus Tablet contains a sugar called lactose. If you are intolerant to lactose or your doctor has asked you to not consume certain sugars, consult your doctor before taking this medicine.
Product Details
Expires on or After
Last Updated on: 28 Feb 2022 | 09:37 AM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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