Glymep Tablet

• If you are allergic to Glibenclamide, Metformin, or any other ingredients of Glymep Tablet.
• If you have liver or kidney problems.
• If you have type 1 diabetes.
• If you are in a diabetic coma.
• If you are suffering from diabetic ketoacidosis (symptoms include fatigue, nausea, frequent urination and muscle stiffness).
• If you are taking a medicine called bosentan to treat your high blood pressure.

• Headache
• Dizziness
• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Sweating
• Shakiness
• Altered taste
• Hunger
• Low blood sugar
• Blurred vision, headache, constipation, confusion, anxiety (uncommon)

Other General Warnings

• You experience severe diarrhoea, vomiting, loss of body fluids.
• You have problems with your heart, liver or kidneys.
• You have uncontrolled diabetes.
• You suffer from dehydration.
• You have type 1 diabetes.
• You experience signs of low blood glucose like dizziness, weakness, rapid heartbeat, sweating, inability to concentrate.
• You experience muscle pain, stomach pain, vomiting, breathing difficulty, low body temperature. This could be a serious condition known as lactic acidosis.
• You consume alcohol regularly.
• You develop a fever or infection.
• You have problems with your adrenal or pituitary glands.
• You are scheduled to have surgery or an operation.
• You are on insulin or any other sulfonylurea medicine.
• You are a woman who does not have periods regularly or at all (premenopausal), as Glymep Tablet can increase the chances of your pregnancy.
• You are above the age of 60 years.
• You have a blood enzyme deficiency (glucose-6-phosphate dehydrogenase deficiency).
• Stop taking this medicine for a short duration if you have severe vomiting or diarrhoea, fever, etc.
• Glymep Tablet is meant for use only in adults and should not be used in patients less than 18 years old.

• Glymep Tablet should be taken as directed by your doctor. Swallow it whole with a glass of water, do not cut, break or chew the medicine. It should be taken with food. It would be best if you took it at a fixed time for optimal results and not consume it more than that prescribed by your doctor.

• Glymep Tablet should be stored at room temperature protected from moisture and heat.
• Keep them out of reach and sight of children and pets.
• Do not use expired or damaged medicines.
• Discard any unused medicine properly, do not flush in the toilet or throw it into the drain.

Overdose

• Excess of Glymep Tablet may lead to lactic acidosis, coma, fits.
• You may experience symptoms like vomiting, stomach pain, muscle cramps, unconsciousness, difficulty in breathing.
• Seek urgent medical help if you feel you have taken too much of this medicine.

Missed a Dose

How Does It Work?

• Glymep Tablet works by the combined action of both its components - Glibenclamide and Metformin.
• Glibenclamide works by stimulating the release of insulin from your pancreas, thus reducing blood sugar.
• Metformin works by decreasing the amount of glucose absorbed from the intestine, lowering the amount of sugar created by the liver, and facilitating the entry of sugar into the cells.

Interactions with other medicines

• Some medicines can affect the way Glymep Tablet works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Especially, if you are taking medicines to treat your blood pressure, diabetes, heart problems, high cholesterol level, mental health problems, cancer, thyroid problems, gout, tuberculosis, fits, infections, glaucoma, stomach ulcers, allergies, blood thinner medicines, prostate problems, pain and inflammation.
• Other medicines like pentoxifylline, oestrogens, progestogens, laxatives, ranolazine, dolutegravir, cimetidine, colesevelam should be used with caution along with Glymep Tablet.
• You should let the doctor or the laboratory person know that you are using this medicine while going for a lab test, as this medicine may interfere with the lab tests.

Interactions with food items