Flexital 400mg Tablet
Flexital 400 MG Description
Flexital tablet is a prescription medicine used to manage peripheral vascular disease, including intermittent claudication and rest pain. Peripheral vascular disease (PAD) is a chronic progressive ci
rculatory problem in which narrowed vessels lead to partial or total peripheral vascular occlusion, resulting in reduced blood flow. Flexital tablet contains Pentoxifylline as its active ingredient. Pentoxifylline works by decreasing the thickness (viscosity) of blood. Hence, improve blood flow in patients with circulatory problems and reduce aching, cramping, and tiredness in the hands and feet. Flexital tablet duration and dosage should be as advised by your doctor. Tell your doctor about all other medications you are taking, as some may affect or be affected by this medicine. Avoid abrupt stoppage of Flexital tablet without consulting your doctor, as it can cause clinical worsening of your condition. Flexital tablet has the following side effects: dizziness, headache, flushing (sense of warmth on the face, ears, and neck), nausea, vomiting, stomach upset, and bloating.
Product Summary
Offer Price | ₹72.01 |
You Save | ₹11.72 (14% on MRP) |
Contains | Pentoxifylline(400.0 Mg) |
Uses | Arterial and arteriovenous circulatory disorders, Claudication associated with peripheral vascular disease. |
Side effects | Dizziness, Headache, Flushing (sense of warmth on the face, ears and neck), Nausea, Vomiting, Stomach upset |
Therapy | DRUGS FOR PERIPHERAL VASCULAR DISEASE |
Uses of Flexital 400 MG
- As per CDSCO and USFDA, the Flexital tablet is used for the following:
- Treatment of arterial and arteriovenous circulatory disorders
- Treatment of Claudication associated with peripheral vascular disease
Contraindications of Flexital 400 MG
- Flexital tablet has the following contraindications:
- If you are allergic to a component of the Flexital tablet, i.e., Pentoxifylline
- If you have coronary artery disease (hardened and narrowed arteries)
- If you have heart disease or heart attack
- If you recently had a retinal or cerebrovascular haemorrhage
- If you have recently had surgery
- If you use medicine to treat or prevent blood clots like warfarin
- If you have severe renal disease
- If you have severe hepatic impairment
Side effects of Flexital 400 MG
- Flexital tablet has the following side effects:
- Dizziness
- Headache
- Flushing (sense of warmth on the face, ears, and neck)
- Nausea
- Vomiting
- Stomach upset
- Bloating
Precautions and Warnings of Flexital 400 MG
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have any allergic reactions after taking the Flexital tablet.
- You have chest pain.
- You notice bloody or tarry stools or coughing up blood.
- You experience any severe side effects persistently.
- You are pregnant or planning to get pregnant.
- You have severe liver impairment.
- You have renal impairment.
- You are taking other prescription medications, herbal products, vitamins, and nutritional supplements or plan to take as there is a chance of interaction.
Mode of Action of Flexital 400 MG
How Does It Work?
Directions for Use of Flexital 400 MG
- Take Flexital tablet exactly as prescribed by the doctor.
- Take Flexital tablet on a regular schedule, preferably at the same time every day.
- Take the Flexital tablet as a whole with a full glass of water. Do not break or chew the tablet.
- Do not exceed the recommended dosage of Flexital tablet as it can lead to overdose.
- Do not take Flexital tablet with other medications without consulting your doctor.
Interactions of Flexital 400 MG
Interactions with other medicines
- Concomitant administration of Flexital tablet and theophylline-containing medicines increases theophylline levels and theophylline toxicity.
- Flexital tablet interaction can intensify the hypoglycaemic action of insulin and oral hypoglycaemic agents and may lead to low blood sugar.
- Flexital tablets may potentiate the effect of antihypertensive agents and may lead to severely low blood pressure.
- Flexital tablets should not be given concomitantly with warfarin as there is an increased risk of bleeding and prolongation of prothrombin time.
- Flexital tablet increases the risk of bleeding in patients taking platelet aggregation inhibitors (such as clopidogrel, eptifibatide, tirofiban, epoprostenol, iloprost, abciximab, anagrelide, NSAIDs other than selective COX-2 inhibitors, acetylsalicylate, ticlopidine, dipyridamole)....
Interactions with food items
- Continue with the usual diet unless instructed by the doctor.
Storage and disposal of Flexital 400 MG
Dosage of Flexital 400 MG
Overdose
Missed a Dose
Content Details
Dr. Zishan Ahmad
Final year MBBS Student
Dr. Varsha Parihar
MBBS, MD (Community Medicine)
Frequently Asked Questions (FAQs)
Q: I have been taking Flexital tablet for a few days, but my symptoms did not resolve. Can I increase the dose?
Q: What else can I do to improve my symptoms apart from taking the Flexital tablet?
Q: Can I discontinue the Flexital tablet on my own after I feel improvement in my symptoms?
Q: When is the best time to take Flexital tablet?
References
- Annamaraju P, Baradhi K. Pentoxifylline [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 25 March 2022]. Available from:
- Gul F, Janzer S. Peripheral Vascular Disease [Internet]. Ncbi.nlm.nih.gov. 2022 [cited 25 March 2022]. Available from:
- DailyMed - PENTOXIFYLLINE tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2022 [cited 25 March 2022]. Available from:
- Trental 400 mg Modified release Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 25 March 2022]. Available from:
- [Internet]. 2022 [cited 25 March 2022]. Available from:
- Drugs H. Pentoxifylline: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 25 March 2022]. Available from:
- [Internet]. 2022 [cited 25 March 2022]. Available from: