Esopel D Capsule

10 Capsule(s) in Strip
MRP 80.70
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Esopel D Capsule Description

Esopel D Capsule is an anti-reflux medicine used to treat gastroesophageal reflux disease (GERD), does not respond to esomeprazole medication alone. GERD occurs due to acid reflux (burning pain or dis...
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Product Summary

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ContainsDomperidone(30.0 Mg),Esomeprazole(40.0 Mg)
UsesAcidity, heartburn, GERD
Side effectsHeadache, dizziness, nausea, vomiting, stomach pain
Check more medicines with composition as Domperidone(30.0 Mg) + Esomeprazole(40.0 Mg)
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Contains same composition as Esopel D Capsule
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Uses of Esopel D Capsule

Esopel D Capsule is used for the treatment of gastroesophageal reflux disease (GERD). GERD is a condition in which there is a reflux of acid from the stomach into the food pipe, causing heartburn, che...
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Contraindications of Esopel D Capsule

  • If you are allergic to esomeprazole or domperidone or any other ingredients of Esopel D Capsule.
  • If you are taking any medicine which might affect the contraction of the heart muscle (QT prolongation).
  • If you have a blockage or tear in the intestine or bleeding in the digestive system.
  • If you are suffering from liver or kidney disorder.
  • If you have severe heart problems such as congestive heart failure, heart rhythm problems, electrolyte imbalance.
  • If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
  • If you are taking medicines such as nelfinavir (used in HIV infection), clarithromycin (antibiotic), ketoconazole (antifungal) or verapamil (used in high blood pressure and chest pain)

Side effects of Esopel D Capsule

  • Headache
  • Dizziness
  • Stomach pain
  • Diarrhoea
  • Dry mouth
  • Giddiness
  • Skin rash

Precautions and Warnings of Esopel D Capsule


Can I take Esopel D Capsule during pregnancy?
Esopel D Capsule should not be used during pregnancy as there is limited information about its safety in human pregnancy. Consult the doctor if you are pregnant or think you may be pregnant or planning to have a baby.

Breast Feeding

Can I take Esopel D Capsule while breastfeeding?
Esopel D Capsule passes into breast milk in small amounts and might affect the baby. Consult the doctor if you are breastfeeding, the doctor might change the medicine, ask you to stop breastfeeding or closely monitor the baby.


Can I drive after consuming Esopel D Capsule?
Esopel D Capsule may make you feel dizzy, sleepy or even blur the vision for a temporary basis. Avoid driving in case feeling unwell or unable to be alert.


Can I consume alcohol while taking the medicine?
Avoid consuming alcohol while on treatment with Esopel D Capsules as it is known to increase acidity and makes the acidity worse.

Other General Warnings

Talk to your doctor if
  • You have liver and kidney-related diseases.
  • You experience stomach pain or indigestion, weight loss, have problems while swallowing, vomit out food or blood after taking Esopel D Capsule.
  • You suffer from black stools or have a stomach tumour.
  • You suffer from fractures or have osteoporosis or taking steroids.
  • You suffer from heart problems and associated symptoms like palpitations, difficulty in breathing, and unconsciousness.
  • You are taking the capsules for long-term treatment (more than three months), the blood magnesium levels may decrease. The doctor may perform regular tests for the same.
  • You develop skin lesions when sun-exposed area after taking the medicine.
  • You have low levels of vitamin B12. The medicine reduces the absorption of vitamin B12 after long term use. Supplements may be needed.
  • Taking Esopel D Capsules for more than one year may increase the chances of bone fractures.
  • It may lead to an increased risk of bacterial infections due to Salmonella and Campylobacter.

Mode of Action of Esopel D Capsule

How Does It Work?

  • Esopel D Capsule works by combined action of its two ingredients. Esomeprazole works by reducing the acid production in stomach by blocking a pump called proton pump present on stomach wall and respon...
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  • Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Directions for Use of Esopel D Capsule

Esopel D Capsule should be taken at least 1 hour before meals. These capsules should be swallowed whole with water. You should take this medicine regularly at a fixed time and as directed by your doct...
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Interactions of Esopel D Capsule

Interactions with other medicines

  • Certain medicines can affect the way Esopel D Capsule works or this Capsule itself can affect the action of other medicines taken at the same time.
  • Especially if you are taking medicines like rilpivirine (Anti-HIV medications), disopyramide (for irregular heart beats), medicines for mental problems, antibiotics, antifungals, medicine used to trea...
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  • Concomitant use of this capsule with medicines used to treat psychiatric illness (diazepam), used to treat fits (phenytoin) is not recommended as it may increase the side effects of the medicines.
  • Medicine used to treat heart failure like digoxin may lead to toxicity when taken with this medicine.
  • If you are taking warfarin (blood-thinner) along with this medicine, caution is needed as there are chances of increased bleeding.

Storage and disposal of Esopel D Capsule

Store Esopel D Capsules below 25°C in a clean and dry place, protected from direct sunlight, moisture, and heat. Keep this medicine away from children and pets. Discard expired medicines or any unused...
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Dosage of Esopel D Capsule


Symptoms of overdose are dizziness, nausea, headache, confusion. If you experience any of the symptoms or think you have taken too much of Esopel D Capsules, then contact your doctor immediately or vi...
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Missed a Dose

If you miss any dose of Esopel D Capsule, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose...
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What is the use of the Esopel D Capsule?

A: Esopel D Capsule is used to treat gastroesophageal reflux disease (GERD) in adults when GERD does not respond to esomeprazole medicine alone. The condition leads to acid regurgitating from the stomach into the food pipe, causing heartburn, chest discomfort and acidity.

Q: Can I take Esopel D Capsule after food?

A: Esopel D Capsule must not be taken after food as food interacts with the absorption of the medicine. It must be taken at least 1 hour before food.

Q: How long does Esopel D Capsule take to show its action?

A: It takes approximately 1 hour after taking a dose for Esopel D Capsule to act. However, this varies among individuals depending on their physiology.

Q: Does Esopel D Capsule cause constipation?

A: Yes, constipation is a common side effect of this combination medicine. It may affect may up to 1 in 10 people who are taking this medicine.
A: Can Esopel D taken twice a day?

Q: The dose and frequency of Esopel D vary among individuals depending on the condition it is being taken for. You should not consume more than the recommended daily dose by the doctor.

Product Details
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Last Updated on: 04 May 2022 | 01:20 PM (IST)

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