Disulfiram 250mg Strip Of 10 Tablets (Intas)
By INTAS PHARMACEUTICALS LTD
10 Tablet(s) in Strip
₹31.71*
16% OFF
₹3.17/tablet
(Inclusive of all taxes)
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Description
Disulfiram 250 mg tablet is used as a part of the treatment plan for alcohol addiction. It causes unpleasant effects like nausea, and flushing of the face when it is taken along with alcohol. These s
ide effects discourage the use of alcohol in chronic alcoholics. Hence, it aids in improving the quality of psychotherapeutic treatment given to manage alcohol addicts. Disulfiram 250 mg tablets should be taken at a dose, as prescribed by the doctor. The complete course of the medicine should be taken. In case you have missed a dose, then you should take it as soon as possible. However, don't take two doses at the same time. You should avoid all forms of alcohol and alcohol-containing substances while you are taking this medicine. The most common side effects of Disulfiram 250 mg tablets are headache, fatigue, drowsiness, changes in vision, numbness and pain in hands or feet, and changes in mood. You should avoid driving, operating any machinery, or doing things that require mental focus. Alcohol de-addiction requires a combination of psychological support, medicines, and counselling sessions. Counselling sessions will help you to stay away from alcohol in stressful events and prevent a relapse while nutritional supplementation shall help to replenish the necessary nutrients in the body.
Product Summary
| Offer Price | ₹31.71 |
| You Save | ₹6.04 (16% on MRP) |
| Contains | Disulfiram(250.0 Mg) |
| Uses | alcohol de-addiction |
| Side effects | nausea, skin rash, stomach pain, drowsiness |
| Therapy | DEADDICTION |
Uses of Disulfiram 250 MG
- Alcohol de-addiction
Contraindications of Disulfiram 250 MG
- Alcohol should not be consumed while taking disulfiram as it leads to unpleasant experiences like nausea, palpitations, chest pain, and low blood pressure levels
- All alcohol-containing substances such as sauces, tonic, or mouthwashes should not be used
- Pre-existing liver diseases should be evaluated before prescribing disulfiram 250 mg tablets. Yellowing of the eyes is a severe side effect of Disulfiram and an indication of damage to the liver
- People with a history of coronary heart disease, hypertension, and heart failure should not take Disulfiram 250 mg tablets
- People who are depressed and have suicidal tendencies should not take this medicine
- Disulfiram should be used with caution if you have pre-existing kidney disease
Side effects of Disulfiram 250 MG
- Drowsiness
- Fatigue
- Abnormal taste
- Rashes on skin
- Changes in vision
- Changes in mood
- Severe stomach pain
- Darkening of urine
Precautions and Warnings of Disulfiram 250 MG
Pregnancy
Q:
Can I take Disulfiram 250 mg during pregnancy?
A:
If you are pregnant or planning for a pregnancy and are prescribed disulfiram tablets, you should consult a doctor.
Breast Feeding
Q:
Can I take Disulfiram 250 mg while breastfeeding?
A:
If you are breastfeeding, you should consult a doctor before starting Disulfiram 250 mg tablets. There aren't enough reports that suggest the presence of Disulfiram in breast milk. However, this medicine should be taken only after consulting a doctor.
Driving
Q:
Can I drive if I have taken Disulfiram 250 mg?
A:
It is not advisable to drive after taking the Disulfiram 250 mg tablet. It can cause drowsiness and blurred vision, hence one should not operate machinery, drive, or perform any activity that requires mental focus.
Alcohol
Q:
Can I consume alcohol with Disulfiram 250 mg?
A:
You should not consume alcohol with Disulfiram 250 mg tablets. Disulfiram inhibits the enzyme required to metabolise alcohol. Hence, it leads to an increase in unpleasant side effects like palpitations, low blood pressure, and flushing on the face.
Other General Warnings
Talk to your doctor if
- You should inform your doctor if you are allergic to disulfiram or any other medicines
- You should inform your doctor about all the medicines that you are taking. This shall prevent any severe interaction between them
- You should mention any history of convulsions
- You should mention any past episodes of depression
Mode of Action of Disulfiram 250 MG
How Does It Work?
Disulfiram blocks the enzyme that breaks down alcohol in the liver. Hence by inhibiting the metabolism of the alcohol, it increases the concentration of an intermediate product. This intermediate product gives rise to unpleasant side effects like palpitations, sweating, and flushing of face. Thus, it reduces the craving to consume alcohol....
Directions for Use of Disulfiram 250 MG
- Disulfiram 250 tablets should be taken as prescribed by the doctor
- Disulfiram 250 tablets should be taken as a whole and not as a crushed powder or crushed tablet.
- This medicine can be taken with or without any food prior to taking the medicine.
- Do not consume alcohol while you are taking disulfiram 250 mg tablets
- It is not advisable to exceed the recommended dose
- In case of any side effects, you should consult a doctor
- Do not discontinue the medicine without consulting a doctor
Interactions of Disulfiram 250 MG
Interactions with other medicines
- Atazanavir: Decreases the therapeutic effect of Disulfiram
- Bacampicillin: Enhances the side effects of Disulfiram
- Benzodiazepines: Increases the side effects of Disulfiram. The combination can have adverse effects on the brain
- Cocaine: Disulfiram may increase the serum concentration of Cocaine
- Diazepam: Disulfiram may increase the serum concentration of Diazepam
- Dronabinol: Disulfiram may enhance the adverse/toxic effect of Dronabinol. Specifically, Disulfiram may cause intolerance to the alcohol present in the dronabinol oral solution
- Flunitrazepam: Disulfiram may increase the serum concentration of Flunitrazepam
- Fosphenytoin: Disulfiram may increase the serum concentration of Fosphenytoin
- Metronidazole: Disulfiram may enhance the adverse/toxic effect of Metronidazole. The combination can have adverse effects on the brain
- Phenytoin: Disulfiram may increase the serum concentration of Phenytoin
- Theophylline: Disulfiram may increase the serum concentration of Theophylline
- Tinidazole: can increase the adverse/toxic effect of Disulfiram
- Tipranavir: Disulfiram may enhance the adverse/toxic effect of Tipranavir. Avoid combination
- Vitamin K antagonists (eg, warfarin): Disulfiram may increase the serum concentration of Vitamin K antagonists
Interactions with food items
- While taking disulfiram, you should stay away from alcohol and alcohol-containing products such as mouth wash, cough medicine, perfumes, and aftershave creams.
Storage and disposal of Disulfiram 250 MG
Keep this medicine packed in the packet or container it came in
This medication should be kept in a cool and dry place, at a temp below 30°C
Store it according to the package or label's directions
The unused drug must be disposed of with caution
Make sure that this medication is not accessible to kids or pets...
Dosage of Disulfiram 250 MG
Overdose
Symptoms of Disulfiram toxicity include nausea, vomiting, abdominal pain, diarrhoea, hypertension, and drowsiness. The symptoms appear within 12 hrs of overdose. You should immediately rush to a nearby emergency room....
Missed a Dose
If you have missed a dose of Disulfiram 250 mg tablets, then you should take it as soon as you remember. However, you should not take two doses at the same time.
Content Details
WRITTEN BY
Dr Tuhina Mishra
MBBS
REVIEWED BY
Dr. Anuj Tiwari
MBBS, DNB Medicine
Frequently Asked Questions (FAQs)
Q: Can one get addicted to Disulfiram 250 mg tablets?
A: Disulfiram 250 mg does not cause addiction. It is used to treat alcohol addiction by inducing unpleasant effects after taking alcohol while being treated with disulfiram.
Q: Can disulfiram effectively decrease craving for alcohol?
A: Disulfiram decreases the enzyme alcohol dehydrogenase which metabolises alcohol. Since alcohol is not metabolised completely, certain intermediate products are formed. These products are responsible for the emergence of symptoms that decrease craving for alcohol. However, counselling sessions should also be conducted to treat alcoholism along with prescribing medicines.
Q: How long does it take for Disulfiram to work?
A: Disulfiram starts acting within a few minutes and its effect lasts for 1-2 weeks after taking the last dose.
References
View All
- DailyMed - Search Results for DISULFIRAM [Internet]. Nih.gov. [cited 2022 Feb 21]. Available
- PubChem. Disulfiram [Internet]. Nih.gov. [cited 2022 Feb 21]. Available from:
- Disulfiram: Generalised tonic-clonic seizures: case report. React Wkly [Internet]. 2018 [cited 2022 Feb 21];1696(1):138–138. Available from:
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Product Details
Brand
DISULFIRAM
Country of Origin
India
Expires on or After
29/11/2027
Manufacturer Details
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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