Clobakem 10mg Tablet
Clobakem 10 MG Description
Clobakem 10 mg tablet is used to treat severe anxiety and uncontrolled epilepsy. The active ingredient in Clobakem 10 mg tablet is clobazam, which belongs to the benzodiazepines group of medicines.
The mode of action of Clobakem 10 mg tablets is by modifying the binding of certain chemicals in the nerve cells. This decreases the abnormal electrical activity at the nerve cell endings, bringing a calming effect on the mind. This also helps in controlling the jerky movements in epilepsy. Side effects of Clobakem 10 mg tablets include sleepiness, dizziness, slow reflexes, increased salivation, unsteady walk, forgetfulness, blurring of vision, and suicidal behaviour. Prolonged use of Clobakem 10 mg or abruptly stopping it may produce serious withdrawal symptoms such as shakiness, agitation, seeing or hearing unreal things, excessive sweating, and anxiety. It is advised for a short duration and stopped gradually towards completion of the medicine course. It is given with caution in older adults because of their high sensitivity to it and the risk of developing side effects such as confusion, behavioural changes, risk of falls, and memory loss. Clobakem should only be taken as the doctor advised, as it is associated with a high potential for dependency and overdosage.
Uses of Clobakem 10 MG
- As per CDSCO, Clobakem 10 mg is used in the treatment of:
- Refractory (uncontrolled) epilepsy (as an additional medicine)
- Severe anxiety of acute or chronic onset
Contraindications of Clobakem 10 MG
- Do not take Clobakem 10 mg tablets:
- If you had an allergic reaction to any medicine in the benzodiazepine group.
- If you had an allergic reaction to clobazam.
- If you had an allergic reaction to the inactive ingredients in Clobakem 10 mg tablets.
- If you have liver or kidney disease.
- If you have an eye disease called glaucoma.
- If you have breathing problems like sleep apnoea or chronic obstructive lung disease.
Side effects of Clobakem 10 MG
- Slow reflexes
- Muscle pain
- Increase in salivation
- Unsteady walk
- Blurring of vision
- Suicidal behaviour
Precautions and Warnings of Clobakem 10 MG
Other General Warnings
- You have breathing problems.
- You have vision problems.
- You have a history of fits.
- You have heart, liver, or kidney disease.
- You have been advised for surgery.
- You have been diagnosed with depression or have suicidal thoughts.
- You have new or worse anxiety or panic attacks.
- You take other medicines for your condition.
- You take herbal medicine or supplements.
- You are pregnant or breastfeeding.
Mode of Action of Clobakem 10 MG
How Does It Work?
Directions for Use of Clobakem 10 MG
- Take Clobakem 10 mg tablets as instructed by the doctor.
- Clobakem 10 mg tablet is to be taken by mouth with a glass of water.
- Swallow the tablet as a whole.
- This medicine can be taken with or without food.
Interactions of Clobakem 10 MG
Interactions with other medicines
- Clobakem 10 mg tablets are known to interact with the following medications.
- Medicines of the group opioids such as oxycodone, codeine, and fentanyl may cause life-threatening side effects if given with Clobakem 10 mg tablets. This may result in severe breathing problems and coma. ...
- Medicines used for contraception increase the levels of clobazam in the blood. This requires adjustment of the dose of Clobakem 10 mg tablet.
- Medicines used to treat acidity such as cimetidine and ranitidine increase the effect of Clobakem 10 mg tablet.
- Medicines used to treat fits such as carbamazepine may decrease the effectiveness of Clobakem 10 mg tablets.
- Medicines used in treating depression such as nefazodone, fluvoxamine, fluoxetine, and imipramine increase Clobakem 10 mg tablet levels in the blood.
- Medicines used to treat fungal infections such as itraconazole and ketoconazole increase the effect of Clobakem tablets.
- Medicines used to treat bacterial and viral infections such as erythromycin, clarithromycin, and ritonavir increase the effect of Clobakem 10 mg tablets.
- Medicine used in treating tuberculosis, such as isoniazid, may interact with Clobakem 10 mg tablets.
- Medicine used for heart conditions such as digoxin may produce toxic effects when given with Clobakem 10 mg tablets.
Storage and disposal of Clobakem 10 MG
Dosage of Clobakem 10 MG
Missed a Dose
Frequently Asked Questions (FAQs)
Q: Can I take Clobakem 10 mg tablets if I have liver disease?
Q: Can I take Clobakem 10 mg safely for as long as I think it is necessary for my condition?
Q: What should I do if I feel tremors and unsteadiness while taking Clobakem 10 mg for my condition?
Q: Can I stop taking Clobakem 10 mg tablets when I feel that all symptoms have subsided?
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- Benzodiazepines drug profile [Internet]. emcdda.europa.eu. 2022 [cited 14 March 2022]
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- Monjanel-Mouterde S, Antoni M, Bun H, Botta-Frindlund D, Gauthier A, Durand A et al. Pharmacokinetics of a Single Oral Dose of Clobazam in Patients with Liver Disease. Pharmacology & Toxicology [Internet]. 1994. 74(4-5): 345-350 [cited 14 March 2022]