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Axiotem 250Mg Strip Of 5 Capsules

5 Capsule(s) in Strip

MRP ₹21264.00

₹18737.60

12% OFF

₹3747.52/capsule (Inclusive of all taxes)
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  • Axiotem 250Mg Strip Of 5 Capsules

Made by

AXIOMMAX ONCOLOGY PVT LTD

Dosage

CAPSULE

Expiry

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Product Summary

Uses
Recurrent malignant gliomas
Side effects
Fatigue, convulsions, headache, reduction in platelet count, alopecia, nausea, vomiting, anorexia and constipation.
Salt Content
Temozolomide(250.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Axiotem capsule is a prescription chemotherapy medicine prescribed by doctors to treat adults with brain tumors such as glioblastoma multiforme or anaplastic astrocytoma. It contains temozolomide, which belongs to a group of medicines called alkylating agents. In the body, it is converted into an active substance that attaches to the genetic material, or DNA, of rapidly dividing brain tumor cells. This damages DNA and causes breaks, stopping tumor cells from dividing properly and causing them to die. This can help slow cancer progression or shrink it.

Axiotem capsule should be swallowed whole with water, at the same time each day. Your doctor will decide the exact dose and duration of your Axiotem capsule treatment. Because it can affect your blood cell counts and liver, your healthcare team will regularly monitor your blood tests and liver enzymes before and during treatment. If capsule of Axiotem capsule are accidentally opened or damaged, do not inhale or come into contact with the contents. If you come into contact with it, wash the affected area with water immediately.

Common side effects during treatment with Axiotem capsule include fatigue, convulsions, headache, reduction in platelet count, alopecia, nausea, vomiting, anorexia and constipation. Serious side effects include myelodysplastic syndrome and secondary malignancies, including myeloid leukemia, severe or long-lasting low blood cell counts, severe liver damage, pneumocystis pneumonia (a serious fungal lung infection), and opportunistic bacterial and viral infections.

Axiotem capsule should not be used during pregnancy, as it can harm the unborn baby. Women should use effective contraception during treatment and for 6 months after the last dose; men with partners who are or could become pregnant should use condoms during treatment and for 3 months after the last dose, and should not donate semen during this time. Avoid breastfeeding during treatment and for 1 week after the last dose. Treatment with Axiotem capsule may affect male fertility. Before starting treatment with Axiotem capsule, tell your doctor about all medicines, supplements, and herbal products you take, and if you have kidney or liver problems. Contact your healthcare team in case of a missed dose or overdose, and if you notice symptoms such as fever, chills, unusual bleeding or bruising, signs of infection, shortness of breath, cough, or breathing changes.

Uses

Axiotem capsule is prescribed by doctors for adult patients with recurrent malignant gliomas such as glioblastoma multiforme or anaplastic astrocytoma.

Contraindications

Do not take Axiotem capsule if
  • You have had an allergic reaction (such as urticaria, allergic reaction including anaphylaxis, toxic epidermal necrolysis, and Stevens-Johnson syndrome) to temozolomide or any other components of Axiotem capsule.
  • You have had an allergic reaction to dacarbazine (another cancer medicine).

Side effects

Serious side effects:
  • Myelodysplastic syndrome and secondary malignancies, including myeloid leukemia
  • Severe or long-lasting low blood cell counts
  • Severe liver damage
  • Pneumocystis pneumonia (a serious fungal lung infection)
  • Serious opportunistic bacterial and viral infections.
Side effects seen during treatment with Axiotem capsule in newly diagnosed glioblastoma:
  • Fatigue, anorexia, dizziness, weakness and headache
  • Confusion, convulsions and memory impairment
  • Blurred vision
  • Allergic reactions
  • Abdominal pain, nausea, vomiting, constipation, diarrhea and inflammation of the inner lining of your mouth
  • Low blood platelet count leading to increased risk of abnormal bleeding
  • Joint pain
  • Insomnia
  • Coughing and shortness of breath
  • Hair loss, dry skin, skin redness, itchy skin and rashes
  • Change in taste perception
Side effects seen during treatment with Axiotem capsule in anaplastic astrocytoma:
  • Nausea, vomiting, constipation and diarrhea
  • Headache, fatigue, fever and weakness
  • Convulsions, dizziness, memory loss, insomnia, muscle weakness on one side of the body, and coordination issues
  • Build-up of excess fluid in the arms, legs, ankles or feet
  • Viral infections
  • Tingling or numbness, excessive sleepiness, muscle weakness, loss of bladder control, problems with balance or coordination, difficulty speaking or understanding speech, seizures, difficulty walking and confusion
  • Excess production of hormones by the adrenal glands
  • Abdominal pain, anorexia and back pain
  • Anxiety and depression
  • Breast pain in women
  • Upper respiratory tract infections, throat and sinus infections and coughing
  • Rashes and itchy skin
  • Urinary tract infections and increased urination
Other side effects:
  • Toxic epidermal necrolysis and Stevens-Johnson syndrome
  • Hypersensitivity reactions, including anaphylaxis
  • Erythema multiforme
  • Lung inflammation and scarring
  • Diabetes insipidus

Precautions and Warnings

Pregnancy

Pregnancy

No. Axiotem capsule can harm an unborn baby and cause birth defects. Use effective birth control during treatment and for 6 months after your last dose. Tell your healthcare team as soon as possible if you become pregnant or think you might be pregnant.

Breast Feeding

Breast Feeding

No. Because of the risk of serious side effects to a nursing baby, you shouldn’t breastfeed during treatment and for 1 week after your last dose ofAxiotem capsule.

Driving

Driving

It is not advisable to drive when undergoing treatment with Axiotem capsule. This medicine causes side effects such as fatigue, nausea, dizziness, and a risk of seizures, making driving unsafe.

Alcohol

Alcohol

Alcohol should be avoided while undergoing treatment with Axiotem capsule since it can worsen side effects such as nausea, anxiety, dizziness, fatigue, and convulsions.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have kidney or liver problems
  • You are pregnant, think you might be pregnant, or are breastfeeding
  • You develop fever, chills, unusual bleeding or bruising, or signs of infection
  • You notice shortness of breath, cough, or breathing changes
  • You’re unsure about your correct dose or how many capsule to take

Directions for Use

  • Your doctor will decide the dosage and duration of Axiotem capsule based on your treatment plan and your specific health condition.
  • Axiotem capsule should be taken by mouth and preferably be taken on an empty stomach or at bedtime to reduce nausea.
  • Swallow the capsule whole with water. Do not open, break, chew, or dissolve the capsule.
  • Take your Axiotem capsule dose at the same time every day.
  • Axiotem capsule should always be prescribed by your doctor; do not take it on your own.

Storage and disposal

  • Store Axiotem capsule at 25°C (77°F); short term temperature variations are allowed between 15°C to 30°C (59°F to 86°F). Store it away from excess heat and moisture.
  • Keep this medication tightly closed, and out of reach of children and pets, and in a safe location.
  • Since Axiotem capsule is a hazardous drug, ask your pharmacist how to safely dispose of unused or expired capsule. Do not discard them in household waste.

Quick Tips

  • Keep records of all blood tests and check-up appointments in a safe place. Your doctor will need these to monitor your blood counts, liver enzymes, and overall response to treatment with Axiotem capsule.
  • If capsule of Axiotem capsule are accidentally opened or damaged, avoid inhalation or contact of the contents with the skin or mucous membranes. In case of contact, wash the affected area with water immediately.
  • Since Axiotem capsule can cause harm to an unborn baby, a pregnancy test may be performed in women of reproductive potential before starting treatment.
  • Women of reproductive potential should use effective contraception during treatment with Axiotem capsule and for 6 months after the last dose.
  • Male patients with pregnant partners or female partners of reproductive potential should use barrier contraception (such as condoms) during treatment with Axiotem capsule and for 3 months after the last dose.
  • Male patients should not donate semen during treatment with Axiotem capsule and for 3 months after the last dose.
  • Axiotem capsule may impair fertility in men of reproductive potential.
  • The safety and effectiveness of Axiotem capsule is not known in children.
  • People 70 and older have a higher chance of developing low blood cell counts when on this medicine.
  • Since Axiotem capsule is a hazardous medicine, do not give it to anyone else, even if they have similar symptoms.

Dosage

Overdose

  • Contact your healthcare team or seek emergency medical help immediately in case of accidental overdose with Axiotem capsule. Do not wait for symptoms to appear.
  • Overdose with Axiotem capsule can cause severe reduction in blood cell counts, fever, multi-organ failure, and risk of severe infections, and may lead to death.
  • Your healthcare team will monitor your blood counts and provide supportive care to manage symptoms and blood cell counts.

Missed a Dose

Do not take a double dose of Axiotem capsule in case of a missed dose. Contact your doctor or healthcare team as soon as possible for guidance.

How does this medicine work?

Axiotem capsule contains temozolomide, a chemotherapy drug in the class of medications called alkylating agents. Temozolomide targets and damages the genetic material, also known as DNA, of rapidly dividing cells, such as the cancer cells found in certain brain tumors, including glioblastoma and anaplastic astrocytoma. In the body, it is converted into an active substance that attaches to the DNA inside these tumor cells. This damages DNA and causes breaks, stopping cells from dividing properly and eventually causing them to die. This way, Axiotem capsule may help shrink or slow the progress of cancer cells.

Interactions

Interactions with other medicines

Tell your doctor about all prescription as well as over-the-counter medicines, supplements, or herbal products you are currently taking or might take to avoid drug interactions with Axiotem capsule.

Interactions with food items

  • Take Axiotem capsule the same way every time, either always with food or always without.
  • A high-fat meal may reduce and delay the absorption of Axiotem capsule.
  • Taking Axiotem capsule on an empty stomach can help reduce nausea.

Frequently Asked Questions (FAQs)

Axiotem capsule can lower your blood cell counts and affect your liver enzyme levels. Your doctor checks your blood cell counts and liver enzymes with blood tests before and during treatment to identify problems early and adjust your dose if needed.
Taking Axiotem capsule at the same time each day helps keep your medicine levels consistent and ensures you take your doses as prescribed.
Axiotem capsule can lower the number of white blood cells, which help your body fight infections. This can weaken your immune system and make you more likely to develop infections during treatment.

References:

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Manufacturer Details

Brand:AXIOTEM

Vendor Details

Fulfillment Information: Axiotem 250 MG Capsule (5) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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