Aplevant 1.5mg Pre-Filled Pen
By LUPIN
Refrigerated
0.5ml Solution For Injection in Pre Filled Pen
₹4765.48
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₹5669.00
16% OFF
₹9530.96/ml
(Inclusive of all taxes)
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Description
Aplevant 1.5mg Pre-Filled Pen is an anti- diabetic medicine. It contains dulaglutide as an active ingredient. It is used for controlling blood sugar levels in type 2 diabetes along with diet and lifestyle modification. It can be used by individuals aged 10 and above. It is also used to reduce the risk of heart attack, stroke, or death in patients with type 2 diabetes with heart conditions. It works by stimulating the release of insulin from the pancreas, thereby helping reduce blood sugar.
The dosage of Aplevant 1.5mg Pre-Filled Pen will depend on your specific condition and whether you are taking other diabetes medications. You may use it at any time of day, with or without food; however, it is advisable to use it on the same day each week to maximize its effectiveness. Your doctor or nurse will instruct you on how and where to inject the medicine, so be sure to follow their instructions carefully.
Do not stop taking this medication without consulting your doctor, as this could result in increased blood glucose levels and expose you to serious complications. Aplevant should be used alongside an appropriate diet and exercise plan to help control high blood glucose.
Store the Aplevant 1.5mg Pre-Filled Pen in the refrigerator until you need it; do not freeze it. The most common side effects include nausea, diarrhea, abdominal pain, and loss of appetite. It can also lead to hypoglycemia (low blood sugar), particularly if you are taking other medications to lower blood sugar. Be sure to recognize the signs of hypoglycemia and know how to manage it.
Before using this medication, discuss with your doctor if you have a history of liver or kidney disease, pancreatitis, or any stomach issues. Inform your doctor about any other medications you may be taking that could interact with this medicine. If you are pregnant or breastfeeding, consult your doctor to determine if it is safe for you to use Aplevant 1.5mg Pre-Filled Pen.
Product Summary
| Offer Price | ₹4765.48 |
| You Save | ₹903.52 (16% on MRP) |
| Contains | Dulaglutide(1.5 Mg/0.5ml) |
| Therapy | ANTI-DIABETIC |
Uses
Treatment of diabetes mellitus.
Contraindications
- If you are allergic to insulin or any of the ingredients of this medicine
- If you are suffering from hypoglycemia (low blood sugar level).
Side effects
- Low blood sugar (Hypoglycaemia)
- Lightheadedness
- Dizziness
- Anxiety
- Nervousness
- Tiredness
- Feeling hungry
- Visual disturbances
- Headache
- Shaking
- Sweating
- Pale skin
- Skin rashes
- Pain, redness, swelling at injection site.
Precautions and Warnings
Pregnancy
Q:
Can I take Aplevant 1.5mg Pre Filled Pen Of 0.5ml Solution For Injection (Pack Of 2) during pregnancy?
A:
- This medicine can be used during pregnancy if your doctor recommends
- However, close monitoring of blood sugar levels is suggested as the dose requirements may change with each trimester of pregnancy.
Breast Feeding
Q:
Can I take Aplevant 1.5mg Pre Filled Pen Of 0.5ml Solution For Injection (Pack Of 2) while breastfeeding?
A:
You can use this while you are breastfeeding.
Driving
Q:
Can I drive if I have consumed Aplevant 1.5mg Pre Filled Pen Of 0.5ml Solution For Injection (Pack Of 2)?
A:
- Insulin is known to cause low blood sugar levels and these can lead to impairment in your driving ability
- Always keep sugar or a bar of chocolate in your car with you while driving
- In case you experience any of the symptoms of low blood glucose levels like dizziness, drowsiness, visual disturbances and sweating, stop driving immediately and have sugar/ juice.
Alcohol
Q:
Can I consume alcohol with Aplevant 1.5mg Pre Filled Pen Of 0.5ml Solution For Injection (Pack Of 2)?
A:
- It is advisable not to consume alcohol when you are taking this medicine as it interferes with the way insulin works
- Consumption of alcohol may lead to an increased risk of both low blood glucose level and high blood glucose level
- Avoid excessive use of alcohol while taking insulin.
Other General Warnings
Talk to your doctor if
- You have recurrent low blood sugar levels
- Be very careful about symptoms of low blood sugar like sweating, anxiety, fast heartbeat, headache, intense hunger, restlessness, dizziness, irritability. If you experience these, immediately have sugar (Do not consume artificial sweeteners). Eat something as soon as possible. Do not take insulin in such a scenario. If still the symptoms persists, seek emergency medical help...
- You have frequent fever and infections
- You have diseases related to liver and kidney
- You have thyroid disorders
- You are switching to different insulin medicine brand
- You have pain, itching and swelling at the injection site, you should continuously change the site of injection
- Avoid doing heavy exercise
- You are planning to change your diet preferences
- You should always carry sugar candy with you
- You are taking insulin but not taking adequate meals, your blood glucose can drop drastically.
Directions for Use
- Take this injection as per the technique suggested by your doctor or nurse
- This injection is to be taken under the skin of the thigh or upper arm or abdomen
- Do not take this injection in vein or in muscles
- Pull a skin, fold up to take this injection
- Wait for at least 6 sec before removing the needle from the injection site
- Always rotate the site of injection, do not take concurrent injections at the same site.
Storage and disposal
- Store between 2°C to 8°C in the refrigerator
- Do not freeze it
- Keep it out of the reach of children
- Do not open the carton of vials to protect it from light
- Any unused portion should not be stored and should be appropriately discarded.
Quick Tips
- Use Aplevant 1.5mg Pre-Filled Pen once weekly on the same day each week, at any time of day, with or without food, to maintain consistent blood glucose control. Administer the injection subcutaneously into the abdomen, thigh, or upper arm, and rotate injection sites each week to reduce the risk of skin irritation....
- Do not mix Aplevant with insulin in the same injection; never inject it into a vein or muscle.
- Always follow the injection technique demonstrated by your healthcare provider.
- Common side effects, such as nausea, vomiting, diarrhea, or reduced appetite, are more likely in the first few weeks and usually improve as the body adjusts to the medication.
- Store the prefilled pen in a refrigerator (2°C–8°C). If needed, it can be stored at room temperature (below 30°C) for up to 14 days; do not freeze or expose it to direct heat.
- Aplevant is most effective when used alongside a healthy diet, regular physical activity, and routine blood sugar monitoring, as advised by your physician.
- Individuals with high blood sugar or diabetes are at risk of getting various health complications, such as eye, kidney, and nerve problems, heart diseases, and stroke. Therefore, it is advisable to take your diabetes medications regularly, make lifestyle changes, exercise regularly, and maintain a healthy weight to control your blood sugar better. You should also regularly check your blood sugar levels....
Dosage
Overdose
- Excess insulin will lead to low blood sugar levels, called hypoglycemia
- Symptoms like dizziness, fainting, sweating and tremors may be seen
- If you have the blood glucometer with you, test immediately and confirm
- Whether or not you test your levels, it is important to take some glucose water/juice/eat sugar or chocolates immediately and then rush to your doctor.
Missed a Dose
- Missed dose may lead to high blood sugar levels which can cause symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, fruity smell from breath, etc.
- If you missed any dose of medicine take it as soon as you remember
- If it's time for your next dose then skip the missed dose and continue with your regular dose schedule
- Do not take a double dose of medicine to compensate the missed one as taking double dose can cause a drastic fall in blood glucose which can be dangerous.
Mode of Action
How Does It Work?
- Insulin is crucial to allow entry of blood glucose into each cell of the body
- Inside the cell, this glucose is used as fuel
- In type 1 diabetes mellitus, the body fails to produce adequate insulin
- This leads to glucose accumulating in the blood and cause high blood glucose
- This medicine lowers blood sugars by stimulating glucose uptake by cells, tissue and muscles, especially by skeletal muscles and fat and by inhibiting glucose production by the liver.
Interactions
Interactions with other medicines
- You may have symptoms of low blood sugar if you are taking other medicines for diabetes, depression (fluoxetine), medicines for fever and pain (salicylates), ramipril, lisinopril
- You may have high blood sugar if you are taking oral contraceptives, thiazide, steroids, thyroxine, medicines used to treat severe diarrhoea and abnormal growth of body organs like octreotide, lanreotide...
- If you are taking a medicine pioglitazone to treat diabetes, be cautious, as some cases of heart attack and heart failure have been reported
- Some medicines block your body's response to low blood sugar, so you may not experience symptoms like headache, hunger pangs, sweating, anxiety when your blood sugar drops. This can lead to a serious fall in blood sugar. Inform your doctor if you are on medicines like Betablockers (Metoprolol, Propranolol, Atenolol), Clonidine, Guanethidine and Reserpine....
Interactions with food items
- This medicine is to be taken 15 mins before meals or after meals
- Maintaining a constant meal pattern is advisable when you are taking insulin
- Avoid skipping or delaying meals when you are taking insulin.
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What food items I should avoid, as I'm a diabetic?
- Avoid maida, white bread, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
- Avoid seetaphal, mango, jack fruit, fruit salads with ice cream, fruit-based desserts
- Avoid cheese, milkshakes, ice creams
- Try to avoid pork, beef, soft drinks, sugarcane juice, sweetened health drinks and beverages.
Q: Can I stop taking Aplevant 1.5mg Pre Filled Pen Of 0.5ml Solution For Injection (Pack Of 2) if I am feeling uncomfortable after taking this medicine?
A: No, you can not stop taking your insulin without speaking with a doctor. It may lead to high blood sugar levels and may worsen your disease condition and land you in complications. In case of side effects or discomfort, talk to your doctor. You may need dose adjustment.
Q: Why should I always change the site for taking this injection?
A: Taking injection at the same site may lead to a lump formation, local irritation and itching. Thus it is advisable not to take injections at the same site or maintain a gap of at least one day.
Q: What other lifestyle modifications I need to consider to manage diabetes?
- Diet should include chapatis, multigrain bread, puffed rice with vegetables, sprouts, roasted grams, plain cooked daal, soups, steamed vegetables, cooked vegetables with less oil, Jamun, orange, guava, apple, watermelon, papaya, cow’s milk, curd, thin buttermilk, fish (grilled, baked or steamed), peanuts, cashew nuts and walnuts(handful)....
- Limit sugar intake
- Brisk walk daily for 30 minutes
- Exercise regularly
- Monitor your blood glucose regularly
- Take your anti-diabetic medication on time.
Q: I develop low blood sugar levels often, what could be the possible reasons?
- Risk factors for developing low blood glucose levels include taking too much insulin, not taking adequate meals or missing meals, too much alcohol consumption, fever and too much exercise
- Some medicines, when used with insulin can result in such episodes like other diabetes medicine glimepiride, medicines used for fever and pain (salicylates), ramipril, etc.
- Report to your doctor about these episodes. You may need a dose of adjustment.
Q: Does the Aplevant 1.5mg Prefilled Pen need to be refrigerated during travel?
A: Ideally, yes. For long-term storage, keep it between 36°F and 46°F (2°C–8°C). However, for travel, a pen can stay at room temperature (up to 86°F or 30°C) for up to 14 days.
Q: Is Aplevant 1.5mg Pre-Filled Pen the same as insulin?
A: No. While both are used in diabetes, they work differently. Insulin is a hormone that replaces what your body cannot make. Aplevant 1.5mg Pre-Filled Pen is a GLP-1 receptor agonist that helps your pancreas release insulin more effectively when blood sugar is high. Because of this, the Aplevant 1.5mg Pre-Filled Pen is typically administered once weekly, whereas insulin is often administered daily.
Q: What is Aplevant 1.5mg Pre-Filled Pen?
A: Aplevant 1.5mg Pre-Filled Pen is an injection containing the anti-diabetic medicine dulaglutide. It is used to control elevated blood sugar levels along with diet and lifestyle modifications.
Q: Can I use Aplevant 1.5mg Pre-Filled Pen for weight loss?
A: No. Aplevant 1.5mg Pre-Filled Pen is an antidiabetic medication and should not be used for weight loss. It does not affect weight reduction. You should never use medicines used for serious health conditions for any purpose other than what they are prescribed for.
Q: Where can I take Aplevant 1.5mg Pre-Filled Pen?
A: Aplevant 1.5mg Pre-Filled Pen can be taken subcutaneously in the abdomen, in the thigh, or in the upper arm. You should change the injection site after every injection.
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Product Details
Brand
APLEVANT
Country of Origin
Italy
Expiry Date
30/10/2026
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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