Aculip Tablet Description
Aculip is a prescription medication used in the treatment of depression and associated anxiety. It is a combination of Amitriptyline and Chlordiazepoxide. This combination is utilised to treat modera
te to severe depression and anxiety. Depression is a medical condition associated with low mood, hopelessness, inability to complete daily activities, difficulty sleeping, or overall sadness. This may be accompanied by anxiety which is a condition of excessive worry and feelings of fear and nervousness. Increased sweating or trembling may be seen. Both of these conditions affect daily activities. Aculip should be taken in the dose and duration prescribed by a medical professional. Aculip should not be stopped abruptly. In case of any side effects, it is advisable to consult the prescribing doctor. For best results, the tablet should be taken at the same time each day.
|You Save||₹13.06 (15% on MRP)|
|Contains||Amitriptyline(25.0 Mg) + Chlordiazepoxide(10.0 Mg)|
|Uses||Treatment of Major Depressive Disorder with moderate to severe anxiety|
|Side effects||Constipation, urinary retention, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing), tiredness|
Uses of Aculip Tablet
- Treatment of Major depressive disorder (MDD)
- Treatment of Moderate to severe anxiety
Contraindications of Aculip Tablet
- It is contraindicated in case of hypersensitivity to either of the components.
- If you have a recent history of heart attack, heart failure, or irregular heart rhythm.
- If you have angle-closure glaucoma.
- If you have epilepsy/seizure disorders patients.
- If you have any pulmonary diseases.
- If you are planning a pregnancy, or are pregnant or breastfeeding.
Side effects of Aculip Tablet
- Urinary retention
- Dry mouth
- Orthostatic hypotension (unanticipated lowering of blood pressure on standing up)
Precautions and Warnings of Aculip Tablet
Other General Warnings
- You must inform your doctor in case you are on any other medications. There are several medicines that may affect the metabolism of this tablet and modify the blood levels. Appropriate dose adjustment is needed....
Mode of Action of Aculip Tablet
How Does It Work?
Directions for Use of Aculip Tablet
- Aculip should be taken as prescribed by the treating physician.
- Consult your doctor before stopping Aculip.
- Unexpected stoppage of the medication can compel withdrawal side effects.
- Swallow Aculip as a whole. Do not granulate, break, or bite this tablet.
- It is recommended to consume Aculip on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of Aculip.
- Inform your doctor regarding other medications you may be taking to review and prevent any medication interaction associated effects.
Interactions of Aculip Tablet
Interactions with other medicines
- Aculip can cause arrhythmias and should not be used with any medications that affect heart rhythm, such as astemizole, cisapride, etc.
- Aculip should not be used with any medications that are known to raise the levels of serotonin as it can result in a fatal condition called serotonin syndrome. These include antidepressants, opioids such as tramadol and fentanyl, lithium, olanzapine, etc....
- Aculip should not be given along with monoamine oxidase inhibitors. If they must be given, a minimum gap of two weeks is required.
- Aculip should not be taken with central nervous system depressants. These include alcohol and other benzodiazepines such as clonazepam and alprazolam.
- Aculip needs to be used with caution along with anaesthetic agents, and it is generally advisable to discontinue the tablet before any major surgery.
Interactions with food items
- Aculip does not have any specific interactions with food.
Storage and disposal of Aculip Tablet
Dosage of Aculip Tablet
Missed a Dose
Frequently Asked Questions (FAQs)
Q: After taking Aculip, I feel very dizzy and tired. I feel it is not suiting me. Can I stop taking it?
Q: I have a chronic problem of backache. Is it okay to take other painkillers while taking this tablet?
Q: Can Aculip cause constipation?
- Thour A, Marwaha R. Amitriptyline. [Updated 2021 Jul 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from:
- Ahwazi HH, Abdijadid S. Chlordiazepoxide. [Updated 2020 Nov 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from:
- Levate (Amitriptyline).