medicine

Actemra 400mg Inj

By ROCHE LIMITED
20ml Solution For Injection in Bottle
MRP 35000.00*
Inclusive of all taxes
Out of Stock
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Tocilizumab
therapy
Therapeutic classification
DRUGS FOR RHEUMATOID ARTHRITIS

Medical Description

Actemra injection contains Tocilizumab. It is an immunosuppressive medicine and belongs to a class of monoclonal antibodies. It is used for the treatment of different diseases where the existing thera...
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    Uses
    Contraindications
    Side effects
    Precautions and Warnings
    Mode of Action
    Directions for Use
    Interactions
    Dosage
    FAQs
    References
uses

Uses of Actemra 400mg Inj

  • Actemra is used for the treatment of Rheumatoid arthritis, Polyarticular-course juvenile idiopathic arthritis & Idiopathic juvenile arthritis when existing therapy is not sufficient.
  • In combination with Methotrexate, to reduce the rate of progression of joint damage and improve physical function.
  • To improve the symptoms like fatigue and other laboratory findings of a rare disease of lymph nodes called Castleman’s disease.
contraindications

Contraindications of Actemra 400mg Inj

If you are allergic to tocilizumab or any other ingredients of this injection.
sideEffects

Side effects of Actemra 400mg Inj

  • Infection of airway and lungs
  • Common cold
  • Headache
  • High blood pressure
  • Cough
  • Shortness of breath
  • Eye infection
  • Mouth ulcer
  • Skin rashes and itching
  • Increased liver enzymes
precautionsAndWarnings

Precautions and Warnings of Actemra 400mg Inj

pregnancy

Pregnancy

Q:
Can I take Actemra injection during pregnancy?
A:
Actemra should not be given during pregnancy unless needed due to lack of safety information. Women of childbearing age should use proper contraception during and after 3 months of the treatment.
breastfeeding

Breast Feeding

Q:
Can I take Actemra injection while breastfeeding?
A:
It is unknown whether Actemra passes into breast milk or not. Consult your doctor if you are breastfeeding your baby.
driving

Driving

Q:
Can I drive if I have taken Actemra injection?
A:
Actemra can give you minor dizziness and drowsiness. Therefore, avoid driving or operating machines if you experience such symptoms.
alcohol

Alcohol

Q:
Can I consume alcohol with Actemra injection?
A:
There is no known interaction between alcohol and Actemra.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have any existing infection or you have developed an infection while on treatment, this medicine changes the body's immune response and can cause serious infections, close monitoring is needed.
  • You have diabetes, lung problem (interstitial lung disease) or inflammation in the digestive tract (diverticulitis).
  • You have a liver disorder and increased laboratory finding of liver enzymes, as this injection is associated with serious liver disorders.
  • You have developed an allergic reaction like rash, itching or swelling after the injection.
  • Your cholesterol level may go up and blood count can be abnormal, close monitoring is advised.
  • You have hepatitis infection or a history of tuberculosis, it should be excluded before starting treatment with Actemra, as it can reactivate tuberculosis.
  • Be cautious if you have high blood pressure and high cholesterol and adhere to the standard treatment.
  • You should not take live vaccines if you on treatment with Actemra.
modeOfAction

Mode of Action of Actemra 400mg Inj

How Does It Work?

Actemra is an immunosuppressive medicine. It works by acting against an inflammatory mediator Interleukin 6 which is produced in a various disease condition.
directionsForUse

Directions for Use of Actemra 400mg Inj

  • Actemra will be given to you as an injection by a doctor or nurse in a hospital or clinic
  • Be careful of any instruction given during the administration and aftercare
interactions

Interactions of Actemra 400mg Inj

Interactions with other medicines

  • If you are taking medicines like Atorvastatin or Simvastatin used for high cholesterol, blood thinners like Warfarin, anti-seizure medicine like Phenytoin, blood pressure medicine like Amlodipine and ...
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  • You should not take any vaccine while on therapy with Actemra.
dosage

Dosage of Actemra 400mg Inj

Overdose

You are less likely to get an overdose of Actemra as it is given to you by a doctor or nurse in a clinic or hospital. Please inform if you feel any discomfort immediately after the administration of t...
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Missed a Dose

The chances of missing a dose of Actemra is rare as you will be monitored closely by a healthcare professional. In case they happen to miss a dose, please inform them.

Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

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Q: What are the side effects of taking Actemra injection?

A: You may experience infections, headache, high blood pressure, cough and infection of airways and lungs. There can be certain side effects which you will not come to know initially because this medicine can suppress the immune response. Discuss with your doctor if you have any underlying infection or any history of hepatitis or tuberculosis.

Q: I have an ulcer problem, can I take this injection?

A: You need to discuss it with your doctor about your condition as there are side effects associated with this medicine which can worsen your condition.
Last Updated on: 31 Jul 2020 | 07:00 PM (IST)
Disclaimer
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