Torasemide / Torsemide
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Molecule Summary
| Uses | High Blood Pressure, Edema (Swelling of Limbs and Body) |
| Therapy | Diuretic |
| Side Effects | Headache, Dizziness, Muscle Pain, Nausea, Constipation |
Assurance
available
Regulated
Molecule Description
Torsemide is a ‘water pill,’ which means it reduces the excess amount of water in the body by way of frequent urination. It belongs to a class of medicines called Diuretic.
Uses
- In reducing the edema associated with congestive heart failure (decreased pumping efficiency of the heart), kidney and liver diseases
- In kidney and liver disease
- Hypertension (elevated blood pressure)
- This medicine can lessen symptoms such as shortness of breath and swelling in your arms, legs, feet (edema) and abdomen (ascites)
Contraindications
When should one not use Torasemide / Torsemide
- Intolerance to Torsemide or any other ingredients of the tablet
- Allergy/ allergic reactions to Sulphonylurea derived medicines (used to treat Type 2 diabetes)
- Patients unable to produce urine (anuria), usually due to severe kidney or liver disease
Side effects
Common side effects of this drug are:
- Excessive urination
- Headache
- Dizziness
- Altered electrolyte levels in the blood
- Chest pain
- Diarrhea
- Running nose (rhinitis)
- ECG abnormalities
- Muscle pain (myalgia) & joint pains (arthralgia)
- Nausea or vomiting
- Indigestion (dyspepsia)
- Skin rash
- Increased cough
- Sore throat
- Sleeplessness
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Your medical history, especially of kidney problems, liver problems, ear problems (hearing), inability to make urine, gout
- Regular monitoring of water, sodium, potassium and other electrolytes is necessary
Mode of Action
How Does It Work?
- Torsemide is called a high-ceiling loop diuretic which means it is more efficient than other medicines in the class and causes more water to be excreted through the kidney (urine)
- Torsemide does this by acting on a structure called ‘loop of Henle’ of the kidney and preventing water reabsorption back into the body
Interactions
Interactions with other medicines
- Aminoglycoside antibiotics (Gentamicin, Amikacin, Tobramycin, Streptomycin, Neomycin, etc.)
- Anticoagulants (blood-thinning medicines e.g. Warfarin)
- Cisplatin (used to treat cancer)
- Digitalis (used to treat irregular heartbeats)
- Pain killers
- Clofibrate (used to lower cholesterol)
- Other Diuretics (e.g. Metolazone)
- Muscle relaxants (Succinylcholine, Tubocurarine)
- Propanolol (used to treat heart disorders)
- Hydantoins (used to treat seizures, e.g. Phenytoin)
Interactions with food items
Efficacy may be reduced when taken close to a meal.
Dosage
Overdose
Inform your doctor immediately in case of overdose. It may cause excess fluid loss leading to low blood pressure, dehydration, confusion, electrolyte imbalances. Inform your doctor immediately. Significant overdose may require hospitalization.
Missed a Dose
If you have missed the dose, then take the missed dose as soon as you remember it. If it is almost time for next dose then skip the missed dose. Do not take a double dose and consult your doctor for further treatment.
Frequently Asked Questions (FAQs)
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