molecule

Tibolone

Molecule Description

Tibolone is a synthetic steroid medicine used for Hormone Replacement Therapy (H...
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uses

Uses of Tibolone

This medicine is used to relieve the symptoms of estrogen deficiency (hot flushes, depression, decreased sex drive), in women who have gone through the menopause. It is also used to prevent osteoporos...
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contraindications

Contraindications of Tibolone

When should one not use Tibolone

  • Women with any history of blood clotting (arterial thromboembolic) disease including stroke, transient ischemic attack, myocardial infarction and angina, breast cancer
  • Allergic to this medicine
  • History of liver disease with abnormal liver enzymes
  • Any vaginal bleeding
  • Any blood clots in the lungs, veins
  • History of any inherited blood disorders (porphyrias)
sideEffects

Side effects of Tibolone

Common side effects of this drug are:

  • Vaginal bleeding or spotting
  • Vaginal discharge
  • Vaginal thrush
  • Vaginal itching
  • Breast tenderness
  • Abnormal hair growth
  • Weight gain
  • Thickening of the inner lining of the uterus (called the endometrium)
precautionsAndWarnings

Precautions and Warnings of Tibolone

pregnancy

Pregnancy

Q:
Can I take Tibolone during pregnancy?
A:
Tibolone is not recommended to use during pregnancy. It is not indicated in women who have not yet undergone menopause. Stop this medication immediately if you think you are pregnant and inform your physician.
breastfeeding

Breast Feeding

Q:
Can I take Tibolone while breastfeeding?
A:
It is not recommended during breastfeeding. Consult with your doctor if you are taking this medicine while breastfeeding.
driving

Driving

Q:
Can I drive if I have consumed Tibolone?
A:
No influence on ability to drive.
alcohol

Alcohol

Q:
Can I consume alcohol with Tibolone?
A:
Alcohol consumption with this medicine causes an increase in the risk of breast cancer. Avoid alcohol while on this treatment.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • History of excessive thickening of uterus (endometriosis)
  • If you have a history of elevated blood pressure, diabetes, gallstones, migraine headaches, asthma
  • You have had any history of breast cancer
  • If you experience any swelling, pain in legs, sudden pain in the chest, blood clots after taking this medicine; stop the treatment immediately and inform your doctor.
modeOfAction

Mode of Action of Tibolone

How Does It Work?

It acts similarly to the natural estrogen, progesterone and testosterone found in the body. This helps restore the balance of hormones in the body and reduces the symptoms of menopause, whether natura...
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interactions

Interactions of Tibolone

Interactions with other medicines

  • Medicine used to treat tuberculosis (Rifampicin)
  • Blood thinners (Warfarin)
  • Medicines used to treat epilepsy (Phenobarbital)

Interactions with food items

It may interact with can broccoli, red wine, cabbage, brussels sprouts, red wine, alcohol, grapefruit juice and cigarette smoke.
dietaryRestrictions

Dietary Restrictions of Tibolone

No information is available on dietary restrictions while you are taking Tibolone, consult your doctor or pharmacist for further information.
dosage

Dosage of Tibolone

Overdose

Seek emergency medical help if you think you have taken too much dose of this medicine. Symptoms of overdose include nausea, vomiting and vaginal bleeding in females may occur.

Missed a Dose

If you missed any doses of medicine, take it as soon as you remember. Skip the missed dose if it is time for your subsequent scheduled dose. Do not take extra medicine of medicine to make up the misse...
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Content Details

WRITTEN BY
doctor

Dr. Rukman Mecca

MBBS, MD (Community Medicine)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

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Q: What should I discuss with my healthcare expert before taking this medicine?

A: You should not use this medicine if you are allergic to it, tell the list of medications you are using and discuss your health condition with your doctor before taking medicine.

Q: When and how to consume medicine?

A: This medicine may be taken with or without food with a glass of water. It should be taken at the same time each day.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)
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